2026/2027 NURS8024 PHARM EXAM 1 ACTUAL
EXAM TEST QUESTIONS & ANSWERS (A+ GRADED
100% VERIFIED) LATEST!!
Gastric acid secretion *acetycholine, histamine, gastrin
by parietal cells of the
gastric mucosa are
stimulated by
Receptor-mediated *the activation of protein kinases,
binding of acetylcholine, which in
histamine, or gastrin turn stimulates the H+/K+-adenosine
results in triphosphatase (ATPase) proton pump
Gastrin and acetylcholine histamine
stimulate release of
receptor binding of gastric acid production
prostaglandin E2 and
somatostatin diminish
,Antacids weak bases that react with gastric
acid to
form water and a salt
→ diminishing gastric
acidity Reduce pepsin
activity - pepsin
inactive at a pH >4
Wide variety* in chemical
composition, acid-neutralizing
capacity, sodium content,
palatability, and price
Acid neutralizing ability* of an
antacid depends on its capacity to
neutralize gastric HCl and on
whether the stomach is full or
empty
• food delays stomach emptying,
allowing more time for the antacid
,to react
, Therapeutic uses of • Symptomatic relief of peptic
antacids ulcer disease (PUD) and
gastroesophageal reflux (GERD)
• May promote
healing of duodenal
ulcers, but not robust
evidence for efficacy
in Tx of acute gastric
ulcers
• Calcium carbonate preparations
• also used as calcium supplements
for the treatment of osteoporosis
Commonly used Classes
antacid drugs • Calcium salts: calcium carbonate:
Tums/Rolaids
• Sodium bicarbonate: Alka-Seltzer
• Aluminum salts - Aluminum
hydroxide: Amphojel; Aluminum
EXAM TEST QUESTIONS & ANSWERS (A+ GRADED
100% VERIFIED) LATEST!!
Gastric acid secretion *acetycholine, histamine, gastrin
by parietal cells of the
gastric mucosa are
stimulated by
Receptor-mediated *the activation of protein kinases,
binding of acetylcholine, which in
histamine, or gastrin turn stimulates the H+/K+-adenosine
results in triphosphatase (ATPase) proton pump
Gastrin and acetylcholine histamine
stimulate release of
receptor binding of gastric acid production
prostaglandin E2 and
somatostatin diminish
,Antacids weak bases that react with gastric
acid to
form water and a salt
→ diminishing gastric
acidity Reduce pepsin
activity - pepsin
inactive at a pH >4
Wide variety* in chemical
composition, acid-neutralizing
capacity, sodium content,
palatability, and price
Acid neutralizing ability* of an
antacid depends on its capacity to
neutralize gastric HCl and on
whether the stomach is full or
empty
• food delays stomach emptying,
allowing more time for the antacid
,to react
, Therapeutic uses of • Symptomatic relief of peptic
antacids ulcer disease (PUD) and
gastroesophageal reflux (GERD)
• May promote
healing of duodenal
ulcers, but not robust
evidence for efficacy
in Tx of acute gastric
ulcers
• Calcium carbonate preparations
• also used as calcium supplements
for the treatment of osteoporosis
Commonly used Classes
antacid drugs • Calcium salts: calcium carbonate:
Tums/Rolaids
• Sodium bicarbonate: Alka-Seltzer
• Aluminum salts - Aluminum
hydroxide: Amphojel; Aluminum
