CHEM 332 EXAM 3 Version A: Final Annotated Key Questions And Answers With
Rationales /Graded A +/2026 Update/100% Correct
amines are classified based on...? - (ANSWER)number of alkyl groups bonded to the nitrogen atom
alkylamine - (ANSWER)has a nitrogen atom that is sp3, pyramidal, with bond angles of approx. 109.5
degrees
arylamine - (ANSWER)has a nitrogen that is bonded to an aromatic ring
aniline - (ANSWER)
nitrogen heterocycle - (ANSWER)has a nitrogen within a cyclic system
pyrrole - (ANSWER)
pyridine - (ANSWER)
piperidine - (ANSWER)
pyrrolidine - (ANSWER)
amine inversion - (ANSWER)if an amine nitrogen has 4 different groups, it is technically a stereogenic
(chiral) center.
At low temps (less than -20 degrees C), it is frozen in one form.
At high temps (> -20 degrees C), loses chirality.
Inversion occur very rapidly at room temperature.
, CHEM 332 EXAM 3 Version A: Final Annotated Key Questions And Answers With
Rationales /Graded A +/2026 Update/100% Correct
amine chirality - (ANSWER)no lone pair = no chirality
e.g. ammonium salt
amines are basic - (ANSWER)unshared pair of electrons on the nitrogen atom will attack protons/acids
amines for hydrogen bonds - (ANSWER)the nitrogen-hydrogen bond is kind of polar
amines form nitrosamines - (ANSWER)
amine boiling point - (ANSWER)stronger hydrogen bonding = higher boiling point
amine water solubility - (ANSWER)fewer carbons = water solubility
aniline - (ANSWER)amine of the benzene
basicity = nucleophilicity - (ANSWER)amines are stronger bases and nucleophiles than other neutral
organic compounds
amide - (ANSWER)amide nitrogen atom is a bad nucleophile
amides are much less basic than amines because the electron pair on N is delocalized
resonance = bad nucleophile - (ANSWER)
aromaticity = bad nucleophile - (ANSWER)pyridine and pyrroles are both aromatic but the nonbonded
electron pair on the N atom of pyrrole is part of the aromatic system
Rationales /Graded A +/2026 Update/100% Correct
amines are classified based on...? - (ANSWER)number of alkyl groups bonded to the nitrogen atom
alkylamine - (ANSWER)has a nitrogen atom that is sp3, pyramidal, with bond angles of approx. 109.5
degrees
arylamine - (ANSWER)has a nitrogen that is bonded to an aromatic ring
aniline - (ANSWER)
nitrogen heterocycle - (ANSWER)has a nitrogen within a cyclic system
pyrrole - (ANSWER)
pyridine - (ANSWER)
piperidine - (ANSWER)
pyrrolidine - (ANSWER)
amine inversion - (ANSWER)if an amine nitrogen has 4 different groups, it is technically a stereogenic
(chiral) center.
At low temps (less than -20 degrees C), it is frozen in one form.
At high temps (> -20 degrees C), loses chirality.
Inversion occur very rapidly at room temperature.
, CHEM 332 EXAM 3 Version A: Final Annotated Key Questions And Answers With
Rationales /Graded A +/2026 Update/100% Correct
amine chirality - (ANSWER)no lone pair = no chirality
e.g. ammonium salt
amines are basic - (ANSWER)unshared pair of electrons on the nitrogen atom will attack protons/acids
amines for hydrogen bonds - (ANSWER)the nitrogen-hydrogen bond is kind of polar
amines form nitrosamines - (ANSWER)
amine boiling point - (ANSWER)stronger hydrogen bonding = higher boiling point
amine water solubility - (ANSWER)fewer carbons = water solubility
aniline - (ANSWER)amine of the benzene
basicity = nucleophilicity - (ANSWER)amines are stronger bases and nucleophiles than other neutral
organic compounds
amide - (ANSWER)amide nitrogen atom is a bad nucleophile
amides are much less basic than amines because the electron pair on N is delocalized
resonance = bad nucleophile - (ANSWER)
aromaticity = bad nucleophile - (ANSWER)pyridine and pyrroles are both aromatic but the nonbonded
electron pair on the N atom of pyrrole is part of the aromatic system
