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What are the 3 tenets of the cell theory? - ANSWER-1) All
organisms are composed of one or more cells
2) The cell is the structural unit of life
3) Cells can arise only by division from a pre-existing cell
major morphological differences between RER and SER -
ANSWER-RER is an extensive organelle with ribosomes
attached on the cytosolic surface. It is composed mostly of
cisternae, which are interconnected flattened sacs. The
,luminal or cisternal space is continuous with the nuclear
envelope outer membrane.
The smooth endoplasmic reticulum (SER) is typically
tubular and forms an interconnecting pipeline system. It
lacks ribosomes.
Cis face vs Trans face (Golgi apparatus) - ANSWER-Cis
face:
-Side nearer to ER (receives proteins)
Trans face:
-Other side (pinches off vesicles to send products)
- exit face
,cisternal maturation model - ANSWER-the cisternae of the
golgi actually progress forward from the cis to the trans
face, carrying and modifying their cargo as they move
vesicular transport model - ANSWER-Cargo is shuttled
from the CGN toward the TGN in vesicles. The actual
stacks remain relatively unchanged.
COPII-coated vesicles - ANSWER-move materials from
the ER "forward" to the ERGIC (intermediate compartment
situated b/w ER and Golgi) and Golgi complex.
COPI-coated vesicles - ANSWER-move materials in a
retrograde direction (1) from the ERGIC and Golgi stack
, "backward" toward the ER and (2) from the trans Golgi
cisternae "backward" to cis Golgi cisternae.
Clathrin-coated vesicles - ANSWER-move materials from
the TGN to endosomes, lysosomes, and plant vacuoles.
Also move materials from the PM to cytoplasmic
compartments along the endocytic pathways. Have also
been implicated in trafficking from endosomes and
lysosomes
exocytosis - ANSWER-process of discharging a secretory
granule to the outside of the cell after a secretory vesicle
fuses with the plasma membrane.