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Complete A+ Guide - Nightingale
Section 1: Cardiovascular System (Questions 1-40)
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A patient with chest pain has an ECG showing ST-segment
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elevation in leads II, III, and aVF. Which coronary artery is most
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likely occluded?
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A. Left anterior descending artery
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B. Left circumflex artery
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C. Right coronary artery n n
D. Posterior descending artery n n
Answer: C. Right coronary arteryn n n n
Rationale: Leads II, III, and aVF represent the inferior wall of
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the heart, which is supplied by the right coronary artery
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(RCA). Anterior wall MI (V1-V4) is supplied by the left
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anterior descending artery (LAD).
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A patient with heart failure and reduced ejection fraction (HFrEF)
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is prescribed carvedilol. What is the primary benefit of beta-
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blockers in heart failure?
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A. Increased heart rate n n
,B. Decreased myocardial oxygen demand and reduced cardiac
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remodeling
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C. Bronchodilation
D. Increased contractility n
Answer: B. Decreased myocardial oxygen demand and
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reduced cardiac remodeling
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Rationale: Beta-blockers decrease heart rate, contractility,
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and blood pressure, reducing myocardial oxygen demand
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and preventing adverse cardiac remodeling. They have
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demonstrated mortality benefit in HFrEF.
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A patient taking warfarin has an INR of 4.5 with no signs of
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bleeding. What is the appropriate management?
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A. Administer vitamin K n n
B. Hold the next dose and monitor INR
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C. Increase the warfarin dose n n n
D. Administer fresh frozen plasma n n n
Answer: B. Hold the next dose and monitor INR
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n Rationale: For INR 4.5 without bleeding, the warfarin
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dose
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should be held and INR monitored. Vitamin K is indicated for
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INR >10 or with signs of bleeding. Fresh frozen plasma is
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reserved for life-threatening bleeding.
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A patient with atrial fibrillation has a CHA₂DS₂-VASc score of 4.
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What is the recommended anticoagulation?
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A. Aspirin 81 mg daily n n n
,B. Aspirin 325 mg daily n n n
C. Direct oral anticoagulant (apixaban, rivaroxaban, edoxaban, or
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dabigatran)
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D. No anticoagulation
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Answer: C. Direct oral anticoagulant (apixaban, rivaroxaban,
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edoxaban, or dabigatran)
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Rationale: DOACs are preferred over warfarin for stroke
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prevention in non-valvular AF with CHA₂DS₂-VASc ≥2 in men
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or ≥3 in women.
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A patient with acute pericarditis would most likely have which
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ECG finding?
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A. ST-segment depression in all leads n n n n
B. Diffuse ST-segment elevation (concave upward) in most leads
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C. Pathologic Q waves n n
D. Tall peaked T waves
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Answer: B. Diffuse ST-segment elevation (concave upward) in
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most leads
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Rationale: Acute pericarditis causes subepicardial
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inflammation, resulting in diffuse ST elevation with
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reciprocal changes in aVR and V1. PR-segment depression
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may also be seen.
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Beck's triad (hypotension, JVD, muffled heart sounds) is classic for:
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A. Tension pneumothorax n
, B. Cardiac tamponade n
C. Pulmonary embolism n
D. Myocardial infarction n
Answer: B. Cardiac tamponade
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Rationale: Beck's triad is the classic presentation of cardiac
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tamponade, requiring immediate pericardiocentesis. Pulsus
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paradoxus is also characteristic.
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A patient with aortic stenosis would most likely have which
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murmur?
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A. Holosystolic murmur at the apex n n n n
B. Crescendo-decrescendo systolic murmur at the right second n n n n n n
intercostal space
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C. Early diastolic decrescendo murmur at the left sternal border
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D. Mid-diastolic rumble at the apex n n n n
Answer: B. Crescendo-decrescendo systolic murmur at the
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right second intercostal space
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Rationale: Aortic stenosis produces a harsh systolic ejection
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murmur best heard at the aortic area (right second
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intercostal space) with radiation to the carotids.
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A patient with peripheral arterial disease (PAD) reports calf pain
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with walking that resolves with rest. This is called:
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A. Rest pain n
B. Intermittent claudication n