NUR 635 ADVANCED PHARMACOLOGY
MIDTERM
EXAM QUESTIONS WITH CORRECT
ANSWERS WITH
RATIONALES LATEST UPDATE
What can be caused if pt started on heparin? - CORRECT ANSWER>>day4,
ordering blood work to check platelet count to observe for
THROMBOCYTOPENIA
coumadin and childbearing aged females - CORRECT
ANSWER>>Interactions with oral contraceptives- must have a back up method
during time you're taking coumadin Pregnancy considerations and coumadin -
CORRECT ANSWER>>Need to monitor anti-Xa levels
biggest food group interaction with coumadin - CORRECT
ANSWER>>Grapefruit, green leafy
veggies. Why? high in vitamin K which counteracts warfarin
Short duration: rapid acting insulin indication, MOA, usage - CORRECT
ANSWER>>Given w/meals
Provide bs control between meals at night
Page 1 of 22
,Can use in conjunction w/intermediate or long-acting agent lispro, aspart,
gluulocene
Short duration: short acting insulin indication, MOA, usage - CORRECT
ANSWER>>Before meals to control postprandial hyperglycemia Infused SQ
via pump humulin/regular
intermediate(humalin/novalin) duration insulin indication, MOA, usage -
CORRECT
ANSWER>>BS control between meals and during the night Only one suitable
for mixing w/short actings basal coverage
Long duration: Insulin glargine U100 - CORRECT ANSWER>>up to 24hrs,
once daily subq dosing, basal coverage for DM1 or Dm2
Neostigmine is a medication uesd to tx what disease/disorder? - CORRECT
ANSWER>>Myastenia Gravis: AI disorder, antibodies destroy communication
btw nerves and muscles. S/S weak skeletal muscles, voluntary muscles,
dysphagia, ptosis
Myasthenia gravis is an AI disorder that may cause what s/s? - CORRECT
ANSWER>>difficulty swallowing
Page 2 of 22
, Medication must cross _____________ to affect CNS - CORRECT
ANSWER>>BBB
Goal in Parkinson's tx is to restore ________________ in brain - CORRECT
ANSWER>>dopamine
MCSE of dopaminergics - CORRECT ANSWER>>sleep attacks,
hallucinations, confusion
Pt on heparin in hospital setting. Why start coumadin 2 days before dc? -
CORRECT ANSWER>>Because coumadin needs a couple days before it starts
working.
Angina: bc pts dev tolerance to long-acting nitroglycerine w/i 1 day. How to
prevent? - CORRECT ANSWER>>Pts must have 8hrs with no nitroglycerine
every days. Hint: At night, remove nitro patch bc no risk of exertional angina
Underlying cause of angina - CORRECT ANSWER>>coronary disease,
athlerosclerosis
Why do we give aspirin in pts w/atherosclerosis? - CORRECT
ANSWER>>Aspirin is an antiplatelet.. Prevents the existing plaques from
getting bigger. Prevents plaque rupture. Cardio protective, prevents stroke, MI,
CVA
Page 3 of 22
MIDTERM
EXAM QUESTIONS WITH CORRECT
ANSWERS WITH
RATIONALES LATEST UPDATE
What can be caused if pt started on heparin? - CORRECT ANSWER>>day4,
ordering blood work to check platelet count to observe for
THROMBOCYTOPENIA
coumadin and childbearing aged females - CORRECT
ANSWER>>Interactions with oral contraceptives- must have a back up method
during time you're taking coumadin Pregnancy considerations and coumadin -
CORRECT ANSWER>>Need to monitor anti-Xa levels
biggest food group interaction with coumadin - CORRECT
ANSWER>>Grapefruit, green leafy
veggies. Why? high in vitamin K which counteracts warfarin
Short duration: rapid acting insulin indication, MOA, usage - CORRECT
ANSWER>>Given w/meals
Provide bs control between meals at night
Page 1 of 22
,Can use in conjunction w/intermediate or long-acting agent lispro, aspart,
gluulocene
Short duration: short acting insulin indication, MOA, usage - CORRECT
ANSWER>>Before meals to control postprandial hyperglycemia Infused SQ
via pump humulin/regular
intermediate(humalin/novalin) duration insulin indication, MOA, usage -
CORRECT
ANSWER>>BS control between meals and during the night Only one suitable
for mixing w/short actings basal coverage
Long duration: Insulin glargine U100 - CORRECT ANSWER>>up to 24hrs,
once daily subq dosing, basal coverage for DM1 or Dm2
Neostigmine is a medication uesd to tx what disease/disorder? - CORRECT
ANSWER>>Myastenia Gravis: AI disorder, antibodies destroy communication
btw nerves and muscles. S/S weak skeletal muscles, voluntary muscles,
dysphagia, ptosis
Myasthenia gravis is an AI disorder that may cause what s/s? - CORRECT
ANSWER>>difficulty swallowing
Page 2 of 22
, Medication must cross _____________ to affect CNS - CORRECT
ANSWER>>BBB
Goal in Parkinson's tx is to restore ________________ in brain - CORRECT
ANSWER>>dopamine
MCSE of dopaminergics - CORRECT ANSWER>>sleep attacks,
hallucinations, confusion
Pt on heparin in hospital setting. Why start coumadin 2 days before dc? -
CORRECT ANSWER>>Because coumadin needs a couple days before it starts
working.
Angina: bc pts dev tolerance to long-acting nitroglycerine w/i 1 day. How to
prevent? - CORRECT ANSWER>>Pts must have 8hrs with no nitroglycerine
every days. Hint: At night, remove nitro patch bc no risk of exertional angina
Underlying cause of angina - CORRECT ANSWER>>coronary disease,
athlerosclerosis
Why do we give aspirin in pts w/atherosclerosis? - CORRECT
ANSWER>>Aspirin is an antiplatelet.. Prevents the existing plaques from
getting bigger. Prevents plaque rupture. Cardio protective, prevents stroke, MI,
CVA
Page 3 of 22
