QUESTIONS AND VERIFIED
CORRECT ANSWERS
GRADED A+
What type of blood flow does adipose tissue have - CORRECT ANSWER-Low blood flow
Can drugs have affinity for bone - CORRECT ANSWER-Yes
What drugs have an affinity for bone - CORRECT ANSWER-Tetracyclines
Factors that influence metabolism - CORRECT ANSWER-Age
Genetics
Pregnancy
Liver disease
Time of day
Environment
Diet
Alcohol
Drug interactions
Kidney function
Chemical reactions in the liver that drugs may undergo - CORRECT ANSWER-Phase I
, Phase II
Phase I chemical reaction in the liver - CORRECT ANSWER-Oxidation, hydrolysis, or reduction to
increase water solubility of drug molecules
Phase II chemical reaction in the liver - CORRECT ANSWER-Conjugation or union of drug
molecule with water-soluble substance
What are prodrugs - CORRECT ANSWER-Medications that become active once they enter the
body
Once administered what happens to prodrugs - CORRECT ANSWER-They are metabolized in the
body into the active compound
What do prodrugs do - CORRECT ANSWER-Help with medication effectiveness and may also be
designed to avoid certain side effects or toxicities
Examples of prodrugs - CORRECT ANSWER-Clopidogrel (Plavix)
Prednisone
Excretion - CORRECT ANSWER-Removal of the drug from the body by the organs of elimination
Most drugs are eliminated by what organ - CORRECT ANSWER-The kidneys
Other organs that eliminate drugs - CORRECT ANSWER-Lungs
GI tract
Sweat and saliva