LATEST QUESTIONS AND
VERIFIED CORRECT
ANSWERS GRADED A+
N/V
True or false
Adding clavulanate to beta lactams increases the risk of diarrhea - CORRECT ANSWER-True
Can lead to C.diff
Beta lactam drug category during pregnancy - CORRECT ANSWER-Category B
Clinical use for beta lactams - CORRECT ANSWER-Commonly prescribed for infections seen in
primary care
What is the first line therapy for acute otitis media and sinusitis - CORRECT ANSWER-Amoxicillin
,First line therapy for streptococcal pharyngitis - CORRECT ANSWER-Penicillin
First line therapy for infection following bites, including human bites - CORRECT ANSWER-
Amoxicillin/clavulanate
Pharmacodynamics of beta-lactams (Cephalosporins) - CORRECT ANSWER-Structurally and
chemically similar to PCNs
Inhibit mucopeptide synthesis in the bacterial cell wall
When do you use first generation cephalosporins - CORRECT ANSWER-Skin and soft tissue
infections
Gram-positive bacteria
-S. aureus
-S. epidermidis
When do you use second generation cephalosporins - CORRECT ANSWER-Active against the
same as first generation plus Klebsiella, Proteus, and E. Coli
When do you use third generation cephalosporins - CORRECT ANSWER-Broader indications
More active against gram-negative bacteria
Characteristic of fourth generation cephalosporin - CORRECT ANSWER-Resistant to beta-
lactmase
,When do you use fourth generation cephalosporins - CORRECT ANSWER-Primarily active against
gram positive bacteria
When do you use fifth generation cephalosporins - CORRECT ANSWER-Similar to third
generation except they are active against MRSA
Fifth generation cephalosporin - CORRECT ANSWER-Ceftaroline
Uses for cephalosporins - CORRECT ANSWER-Use for therapeutic failure in AOM
What do first generation cephalosporins treat - CORRECT ANSWER-Strep pharyngitis
Skin infections
What medications can be prescribed as a second line drug for UTIs - CORRECT ANSWER-
Cephalexin
Cefpodoxime
Cefixime
Uses for Ceftriaxone and cefixime - CORRECT ANSWER-General condition in GC/Chlamydia
infection
What medications are used for community acquired pneumonia - CORRECT ANSWER-
Cefpodoxime
Cefuroxime
, Parenteral Ceftriaxone followed by oral Cefpodoxime
Pharmacodynamics of fluoroquinolones - CORRECT ANSWER-Interfere with bacterial enzymes
required for synthesis of bacterial DNA
What medication group are noted for extensive gram-negative activity - CORRECT ANSWER-
Fluoroquinolones
True or false
Children under the age of 18 can take Fluoroquinolones - CORRECT ANSWER-False
True or false
Fluoroquinolones have increasing resistance because of overprescribing - CORRECT ANSWER-
True
Can no longer be used for gonorrhea or resistant TB
Pharmacokinetics of Fluoroquinolones - CORRECT ANSWER-Well absorbed
Take on an empty stomach for best absorption
ADRs of Fluoroquinolones - CORRECT ANSWER-Black box warning- avoid when less toxic
alternatives available