MN553 Unit 7 Quiz
QUESTIONS AND VERIFIED
CORRECT ANSWERS
GRADED A+
ARB ADRs - CORRECT ANSWER-Similar to ACEs without the cough (typically)
ARB monitoring - CORRECT ANSWER-Similar to ACE
Orthostasis with dose changes
ARB patient education - CORRECT ANSWER-Do not double doses
Watch for hypotension
Example of a direct renin inhibitor - CORRECT ANSWER-Alsikiren (Tekturna)
Tekturna MOA - CORRECT ANSWER-Works on the RAAS
Inhibits renin release (stops)
,Tekturna uses - CORRECT ANSWER-HTN
Awaiting word on HF
Not same MI indication as ACEs and ARBs
True or false
Tekturna has the same renal protective properties as ACEs - CORRECT ANSWER-False
When a patient is on an ACE and creatinine rises what should you do - CORRECT ANSWER-
Discontinue medication
True or false
Tekturna shares the same issues in pregnancy as ACEs and ARBS but fewer issues with K+ and
cough - CORRECT ANSWER-True
Neprilysin inhibitor medications - CORRECT ANSWER-Sacubitiril
Valsartan (Entresto)
Neprilysin inhibitor indications - CORRECT ANSWER-Decreases hospitalizations and death in
chronic HF
(EF less than 40%)
,Taken in place of ACE or ARB
Not given with BBs
Neprilysin inhibitor outcomes - CORRECT ANSWER-Increases renal blood flow and improves
diuresis
What is the washout time between using Neprilysin inhibitors and ACEs/ARBs/BBs - CORRECT
ANSWER-36 hours
Calcium channel blockers MOA - CORRECT ANSWER-Functionally act as vasodilators, lowering
calcium influx into smooth muscle
What is the first choice of drug class for AA with HTN - CORRECT ANSWER-CCBs
Can CCBs be used as add on medications - CORRECT ANSWER-Yes
CCB MOA - CORRECT ANSWER-Metabolized by the liver
CCB ARDs - CORRECT ANSWER-Very constipating
Can cause dizziness
HA
Edema
, Rash
Gingival hyperplasia
CCB monitoring - CORRECT ANSWER-Verapamil has the strongest negative inotropic effect and
should be avoided in patients with HF
Benefits of CCB/ACE combination versus high dose CCB alone - CORRECT ANSWER-Decreases
peripheral edema by 50%
Function of digoxin - CORRECT ANSWER-High selective inhibitor of the adenosine triphosphate
(ATPase) system
Inhibition of ATPase pump from digoxin results in what - CORRECT ANSWER-Sodium and
calcium buildup inside the cell which leads to increased contractility of heart muscle
Considerations when dosing digoxin - CORRECT ANSWER-Initiate therapy at the lost dose
possible
Therapeutic levels of digoxin - CORRECT ANSWER-0.8-2.0 ng/mL.
Toxic level of digoxin - CORRECT ANSWER->2.4 ng/mL.
What happens when serum concentrations of digoxin are greater than 1mg/ml - CORRECT
ANSWER-Increase mortality
True or false
QUESTIONS AND VERIFIED
CORRECT ANSWERS
GRADED A+
ARB ADRs - CORRECT ANSWER-Similar to ACEs without the cough (typically)
ARB monitoring - CORRECT ANSWER-Similar to ACE
Orthostasis with dose changes
ARB patient education - CORRECT ANSWER-Do not double doses
Watch for hypotension
Example of a direct renin inhibitor - CORRECT ANSWER-Alsikiren (Tekturna)
Tekturna MOA - CORRECT ANSWER-Works on the RAAS
Inhibits renin release (stops)
,Tekturna uses - CORRECT ANSWER-HTN
Awaiting word on HF
Not same MI indication as ACEs and ARBs
True or false
Tekturna has the same renal protective properties as ACEs - CORRECT ANSWER-False
When a patient is on an ACE and creatinine rises what should you do - CORRECT ANSWER-
Discontinue medication
True or false
Tekturna shares the same issues in pregnancy as ACEs and ARBS but fewer issues with K+ and
cough - CORRECT ANSWER-True
Neprilysin inhibitor medications - CORRECT ANSWER-Sacubitiril
Valsartan (Entresto)
Neprilysin inhibitor indications - CORRECT ANSWER-Decreases hospitalizations and death in
chronic HF
(EF less than 40%)
,Taken in place of ACE or ARB
Not given with BBs
Neprilysin inhibitor outcomes - CORRECT ANSWER-Increases renal blood flow and improves
diuresis
What is the washout time between using Neprilysin inhibitors and ACEs/ARBs/BBs - CORRECT
ANSWER-36 hours
Calcium channel blockers MOA - CORRECT ANSWER-Functionally act as vasodilators, lowering
calcium influx into smooth muscle
What is the first choice of drug class for AA with HTN - CORRECT ANSWER-CCBs
Can CCBs be used as add on medications - CORRECT ANSWER-Yes
CCB MOA - CORRECT ANSWER-Metabolized by the liver
CCB ARDs - CORRECT ANSWER-Very constipating
Can cause dizziness
HA
Edema
, Rash
Gingival hyperplasia
CCB monitoring - CORRECT ANSWER-Verapamil has the strongest negative inotropic effect and
should be avoided in patients with HF
Benefits of CCB/ACE combination versus high dose CCB alone - CORRECT ANSWER-Decreases
peripheral edema by 50%
Function of digoxin - CORRECT ANSWER-High selective inhibitor of the adenosine triphosphate
(ATPase) system
Inhibition of ATPase pump from digoxin results in what - CORRECT ANSWER-Sodium and
calcium buildup inside the cell which leads to increased contractility of heart muscle
Considerations when dosing digoxin - CORRECT ANSWER-Initiate therapy at the lost dose
possible
Therapeutic levels of digoxin - CORRECT ANSWER-0.8-2.0 ng/mL.
Toxic level of digoxin - CORRECT ANSWER->2.4 ng/mL.
What happens when serum concentrations of digoxin are greater than 1mg/ml - CORRECT
ANSWER-Increase mortality
True or false
