CELL BIO EXAM 1 FALL 2016
Correct answers are indicated in RED text
1) The endosymbiosis hypothesis concerns which of the following organelles ?
a) nucleus and mitochondria
b) nucleus and chloroplasts
c) nucleus and lysosome
d) mitochondria and chloroplasts
e) mitochondria and lysosomes
2) Is the following statement True or False? “Only the extracellular domains of
membrane glycoproteins are glycosylated.”
a) The statement is True
b) The statement is False
3) Which of the following diseases is NOT classified as an Amyloidosis?
a) Transmittable Spongiform Encephalopathies (e.g., "Mad Cow")
b) Alzheimer's Disease
c) Huntington's Disease
d) Kuru
e) All of the above are classified as Amyloidoses
4) Which of the following histones is NOT a component of the nucleosome?
a) histone H1
b) histone H2A
c) histone H2B
d) histone H3
e) histone H4
5) When metaphase chromosomes are stained by the Giemsa method, unique patterns of dark
and light bands appear on each of the chromosomes. The dark bands indicate regions of...
a) high G-C content
b) high A-T content
c) high gene expression
d) open reading frames (genes)
e) telomeres
, 6) In a Lineweaver-Burk plot of the dependence of enzyme velocity on substrate concentration,
what is the value of the function at X=0 (i.e., the Y-intercept)?
a) -Vmax d) -1/Km
b) -1/Vmax e) 1/Km
c) 1/Vmax
7) Which of the following is one way in which a misfolded protein might be recognized by the
protein surveillance machinery of the cell?
a) exposed non-polar amino acid side chains
b) exposed polar amino acid side chains
c) too many amino acids
d) too many beta sheets
e) too many alpha helices
8) Acetylation of the ε-amino group of lysine 9 on the histone H3 component of
a nucleosome usually results in which of the following?
a) silencing of the associated gene
b) removal of the associated gene
c) increased transcription of the associated gene
d) decreased translation of the protein encoded by the associated gene
e) there is no lysine 9 on histone H3
9) What is a "Stokes Shift"?
a) a component of the gear box in a 1957 Chevy Bellaire
b) a dance move developed by Fred Astaire and Ginger Stokes Rogers
c) a gravitational anomaly in the Crab Nebula
d) a change in the temperature of spontaneous combustion of a tertiary alcohol
e) the difference between the peak absorbance and peak emission wavelengths of
a fluorochrome
10) Domains of proteins that are recombined through gene duplication to form proteins with
new combinations of functionality are called ...
a) motifs
b) modules
c) cassettes
Correct answers are indicated in RED text
1) The endosymbiosis hypothesis concerns which of the following organelles ?
a) nucleus and mitochondria
b) nucleus and chloroplasts
c) nucleus and lysosome
d) mitochondria and chloroplasts
e) mitochondria and lysosomes
2) Is the following statement True or False? “Only the extracellular domains of
membrane glycoproteins are glycosylated.”
a) The statement is True
b) The statement is False
3) Which of the following diseases is NOT classified as an Amyloidosis?
a) Transmittable Spongiform Encephalopathies (e.g., "Mad Cow")
b) Alzheimer's Disease
c) Huntington's Disease
d) Kuru
e) All of the above are classified as Amyloidoses
4) Which of the following histones is NOT a component of the nucleosome?
a) histone H1
b) histone H2A
c) histone H2B
d) histone H3
e) histone H4
5) When metaphase chromosomes are stained by the Giemsa method, unique patterns of dark
and light bands appear on each of the chromosomes. The dark bands indicate regions of...
a) high G-C content
b) high A-T content
c) high gene expression
d) open reading frames (genes)
e) telomeres
, 6) In a Lineweaver-Burk plot of the dependence of enzyme velocity on substrate concentration,
what is the value of the function at X=0 (i.e., the Y-intercept)?
a) -Vmax d) -1/Km
b) -1/Vmax e) 1/Km
c) 1/Vmax
7) Which of the following is one way in which a misfolded protein might be recognized by the
protein surveillance machinery of the cell?
a) exposed non-polar amino acid side chains
b) exposed polar amino acid side chains
c) too many amino acids
d) too many beta sheets
e) too many alpha helices
8) Acetylation of the ε-amino group of lysine 9 on the histone H3 component of
a nucleosome usually results in which of the following?
a) silencing of the associated gene
b) removal of the associated gene
c) increased transcription of the associated gene
d) decreased translation of the protein encoded by the associated gene
e) there is no lysine 9 on histone H3
9) What is a "Stokes Shift"?
a) a component of the gear box in a 1957 Chevy Bellaire
b) a dance move developed by Fred Astaire and Ginger Stokes Rogers
c) a gravitational anomaly in the Crab Nebula
d) a change in the temperature of spontaneous combustion of a tertiary alcohol
e) the difference between the peak absorbance and peak emission wavelengths of
a fluorochrome
10) Domains of proteins that are recombined through gene duplication to form proteins with
new combinations of functionality are called ...
a) motifs
b) modules
c) cassettes
