NEOPLASIA
1. malignant neoplasms
a. are independent of hormonal influence
b. are always composed of homogenous cell lines
c. arise from differentiated cells by a process of anaplasia
d. display abnormal nuclei with pale nucleoli
e. typically are more rapidly growing than benign neoplasms
2. Regarding metastasis
a. All carcinomas have the ability to metastasise
b. Highly invasive carcinomas rarely metastasise
c. Carcinomas typically spread via lymphatics compared with
haematogenous spread
d. Tumour cells develop increased cohesiveness of their cell surface in the
formation of cancer cell emboli
e. Cells involved in lymphatic dissemination release degradative enzymes
3. Which of the following tumour is benign
a. Chondrosarcoma
b. Osteochondroma
c. Chondroblastoma
d. Ewing’s tumour
e. None of the above
4. A 50yo woman presents with back pain, Xrays suggest a malignant deposit in
T10. The least likely primary would be
a. breast
b. ovary
c. thyroid
d. kidney
e. colon
5. Which of the following is malignant
a. Squamous cell papilloma
b. Hydatidiform mole
c. Chondroma
d. Mature teratoma
e. Bronchial carcinoid
6. All of the following are precancerous except
a. Chronic gastritis of pernicious anaemia
b. Solar keratosis
c. Crohn’s disease
d. Leukoplakia
e. Chronic UC
, 7. with regard to tumours
a. dysplasia always progresses to cancer
b. cystic teratomas are malignant
c. squamous papillomas are benign
d. the presence of mitoses indicates neoplasia
e. hypochromasia is characteristic of anaplasia
8. Metastasis
a. Unequivocally proves malignancy
b. Is proven by LN enlargement adjacent to a tumour
c. Of breast cancer is usually to supraclavicular LN
d. Is the commonest presentation of melanoma
e. All of the above
9. The most common cause of cancer death in women is
a. Colorectal cancer
b. Lung cancer
c. Pancreatic cancer
d. Breast cancer
e. Lymphoproliferative tumours
10. The following viruses are considered to be oncogenic
a. Hepatitis B
b. Hepatitis C
c. EBV
d. HPV
e. All of the above
11. Features that help differentiate benign from malignant tumours include all except
a. The degree of both morphological and functional differentiation of the
cells
b. The number of mitoses
c. The presence or absence of a capsule
d. The number of cells per unit area
e. The formation of multinucleate giant cells
1. malignant neoplasms
a. are independent of hormonal influence
b. are always composed of homogenous cell lines
c. arise from differentiated cells by a process of anaplasia
d. display abnormal nuclei with pale nucleoli
e. typically are more rapidly growing than benign neoplasms
2. Regarding metastasis
a. All carcinomas have the ability to metastasise
b. Highly invasive carcinomas rarely metastasise
c. Carcinomas typically spread via lymphatics compared with
haematogenous spread
d. Tumour cells develop increased cohesiveness of their cell surface in the
formation of cancer cell emboli
e. Cells involved in lymphatic dissemination release degradative enzymes
3. Which of the following tumour is benign
a. Chondrosarcoma
b. Osteochondroma
c. Chondroblastoma
d. Ewing’s tumour
e. None of the above
4. A 50yo woman presents with back pain, Xrays suggest a malignant deposit in
T10. The least likely primary would be
a. breast
b. ovary
c. thyroid
d. kidney
e. colon
5. Which of the following is malignant
a. Squamous cell papilloma
b. Hydatidiform mole
c. Chondroma
d. Mature teratoma
e. Bronchial carcinoid
6. All of the following are precancerous except
a. Chronic gastritis of pernicious anaemia
b. Solar keratosis
c. Crohn’s disease
d. Leukoplakia
e. Chronic UC
, 7. with regard to tumours
a. dysplasia always progresses to cancer
b. cystic teratomas are malignant
c. squamous papillomas are benign
d. the presence of mitoses indicates neoplasia
e. hypochromasia is characteristic of anaplasia
8. Metastasis
a. Unequivocally proves malignancy
b. Is proven by LN enlargement adjacent to a tumour
c. Of breast cancer is usually to supraclavicular LN
d. Is the commonest presentation of melanoma
e. All of the above
9. The most common cause of cancer death in women is
a. Colorectal cancer
b. Lung cancer
c. Pancreatic cancer
d. Breast cancer
e. Lymphoproliferative tumours
10. The following viruses are considered to be oncogenic
a. Hepatitis B
b. Hepatitis C
c. EBV
d. HPV
e. All of the above
11. Features that help differentiate benign from malignant tumours include all except
a. The degree of both morphological and functional differentiation of the
cells
b. The number of mitoses
c. The presence or absence of a capsule
d. The number of cells per unit area
e. The formation of multinucleate giant cells
