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What is Acute Glomerulonephritis (AGN)? Answer: An immune process that injures
glomeruli, often following a post-streptococcal infection.
What is the most common cause of AGN? Answer: Strep A
What can Post strep A AGN also cause? Answer: Impetigo (contagious skin rash)
Normal specific gravity and PH in urine: Answer: PH: 5-9
Specific Gravity: 1.001 - 1.020
When does AGN typically develop after a strep infection? Answer: About 10-21 days.
What age group has the peak onset of AGN? Answer: Children around 6-7 years old.
Symptoms of AGN Answer: Hematuria, edema, hypertension, Headache, low grade
fever, cloudy and very dark colored urine
AGN edema can cause what? Answer: Pulmonary edema; get chest xrays
What is the Antistreptolysis O Titer test? (ASO) Answer: Tests for recent strep
What do you prioritize for AGN pt care? Answer: Frequent VS (check for HTN)
Strict Is and Os
Asses for pulmonary edema
Daily weights
Low sodium diet
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, What lab findings are associated with AGN? Answer: High BUN and creatinine, Low
glomerular filtration rate.
What meds are used for AGN? Answer: Antibiotics, Antipyretics, Diuretics
What is the most frequent cause of AKI and failure in peds? Answer: Hemolytic Uremic
Syndrome
What is the classic triad of Hemolytic Uremic Syndrome (HUS)? Answer: Hemolytic
anemia, thrombocytopenia, and acute renal injury. (Bruising, headache, pale skin,
vomiting, bloody diarrhea, prolonged bleeding)
What common bacteria tends to cause HUS after GI upset? Answer: E. coli from
undercooked meats or unpasteurized products aswell as contaminated swimming water
Why does Ecoli cause HUS? Answer: A Specific strain of Ecoli contains a toxin that
kills blood cells, and harms kidney cells
HUS changes in VS Answer: High BP, High RR, High HR
How do you manage HUS? Answer: Provide fluids and electrolytes
Treat anemia, thrombocytopenia, AKI
(Usually use Packed RBC for anemia)s
When blood and protein are found in urine together what does it usually indicate?
Answer: Acute Glomerulonephritis
What is the kidney disorder characterized by massive protein loss in the urine. This
happens because there is damage to the glomeruli that causes it to become permeable
allowing more protein to pass Answer: Nephrotic syndrome
What is the type of protein being lost in nephrotic syndrome? Answer: Albumin
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