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,Based on the University of Alabama Capstone College of Nursing curriculum,
NUR 521 Advanced Pharmacology Quiz 6 typically covers antimicrobial agents,
antifungals, and related anti-infective therapy. This comprehensive guide
provides 50 practice questions with correct answers and detailed rationales to
help you prepare for success.
Part 1: Antifungal Medications (Questions 1-15)
s s s s s
1. sA spatient sis sprescribed sAmphotericin sB sfor ssystemic smucormycosis.
sWhich sbaseline sdata smust sthe s nurse scollect sbefore sinitiating stherapy?
A. sLiver sfunction stests sand shemoglobin
B. sKidney sfunction stests sand sCBC
C. sThyroid sfunction stests sand selectrolytes
D. sCoagulation sstudies sand scardiac senzymes
Answer: sB s– sKidney sfunction stests sand sCBC
Rationale: sAmphotericin sB sis sassociated swith ssignificant snephrotoxicity sand sbone
smarrow ssuppression. sBaseline skidney sfunction stests s(BUN, screatinine) sand
scomplete sblood scount s(CBC) sare scritical sto sestablish sbefore sstarting stherapy sto
smonitor sfor sthese sadverse seffects s.
2. sA spatient sreceiving sAmphotericin sB sdevelops sfever sand schills sduring sthe
sinfusion. sWhat sis s the snurse's spriority saction?
A. sStop sthe sinfusion simmediately sand snotify sthe sprovider
B. sAdminister sdiphenhydramine sand sacetaminophen sas spremedication
C. sSlow sthe sinfusion srate sto shalf sthe sordered srate
D. sFlush sthe sline swith snormal ssaline
Answer: sB s– sAdminister sdiphenhydramine sand sacetaminophen sas
spremedication
Rationale: sMild sinfusion sreactions s(fever, schills, srigors) sare scommon swith
sAmphotericin sB. sThese scan sbe smanaged swith s premedication susing
, sdiphenhydramine s(Benadryl) sand sacetaminophen sbefore ssubsequent sdoses.
sStopping sthe sinfusion sis snot snecessary sfor smild sreactions s.
3. sA spatient's screatinine slevel srises sto s3.8 smg/dL sduring sAmphotericin sB
stherapy. sWhat sis sthe sappropriate snursing saction?
A. sContinue sthe smedication sas sprescribed
B. sNotify sthe sprovider sfor spossible sdose sreduction
C. sAdminister sIV sfluids sat s250 smL/hour
D. sDiscontinue sthe smedication simmediately
Answer: sB s– sNotify sthe sprovider sfor spossible sdose sreduction
Rationale: sAmphotericin sB sis snephrotoxic. sA screatinine slevel sof s3.8 smg/dL
sindicates ssignificant srenal simpairment sand srequires sdose sreduction sor
sconsideration sof salternative stherapy. sThe sprovider sshould sbe snotified
simmediately s.
4. sWhich smedications sshould sbe savoided swhile sa spatient sis sreceiving
sAmphotericin sB?
A. sBeta-blockers sand scalcium schannel sblockers
B. sAminoglycosides sand sother snephrotoxic sdrugs
C. sStatins sand sfibrates
D. sAnticoagulants sand santiplatelets
Answer: sB s– sAminoglycosides sand sother snephrotoxic sdrugs
Rationale: sAminoglycosides s(gentamicin, stobramycin) shave scompounded
snephrotoxicity swhen sused swith sAmphotericin s B. sConcurrent suse ssignificantly
sincreases sthe srisk sof sacute skidney sinjury sand sshould sbe savoided swhenever
spossible s.