Study Guide
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University of Alabama Capstone College of
Nursing
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,Based on the University of Alabama Capstone College of Nursing
curriculum, NUR 521 Advanced Pharmacology Module 1 covers fundamental
principles of pharmacology, including pharmacokinetics, pharmacodynamics,
legal and ethical prescribing, controlled substances, and individualized
therapy across the lifespan .
Part 1: Pharmacokinetics (Questions 1-15)
s s s s
Question s1
The sstudy sof sthe smovement sof sdrugs sthrough sthe sbody sis sknown sas:
A. sPharmacodynamics
B. sPharmacokinetics
C. sPharmacogenomics
D. sPharmacotherapeutics
Answer: sB s– sPharmacokinetics
Rationale: sPharmacokinetics sis sthe sstudy sof sthe smovement sof sdrugs sthrough sthe
sbody. sIt sanswers sthe squestion s"What sdoes sthe sbody sdo sto sthe sdrug?" s.
Question s2
What sare sthe sfour sprocesses sof spharmacokinetics?
A. sAbsorption, sdistribution, smetabolism, sexcretion
B. sIngestion, sdigestion, sabsorption, selimination
C. sActivation, scirculation, sdegradation, sexcretion
D. sUptake, sbinding, sbreakdown, sremoval
Answer: sA s– sAbsorption, sdistribution, smetabolism, sexcretion
Rationale: sThe sfour sprocesses sof spharmacokinetics sare sabsorption s(movement
sfrom ssite sof sadministration sinto sblood), sdistribution s(movement sfrom sblood sto
stissues), smetabolism s(enzymatically smediated salteration sof sdrug sstructure), sand
sexcretion s(movement sof sdrugs sand smetabolites sout sof sthe sbody) s.
, Question s3
What sis sbioavailability?
A. sThe samount sof sdrug sthat sis sexcreted sunchanged sin surine
B. sThe samount sof sactive sdrug sthat sreaches ssystemic scirculation sfrom sits ssite sof
sadministration
C. sThe spercentage sof sdrug sthat sbinds sto splasma sproteins
D. sThe srate sat swhich sa sdrug sis smetabolized sby sthe sliver
Answer: sB s– sThe samount sof sactive sdrug sthat sreaches ssystemic scirculation
sfrom sits ssite sof sadministration
Rationale: sBioavailability sis sthe samount sof sactive sdrug sthat sreaches sthe ssystemic
scirculation sfrom sits ssite sof sadministration. sDifferent sdrug scompanies suse sdifferent
sfillers sand sbinders s(inactive singredients) sthat schange sbioavailability s.
Question s4
Explain show sthe ssame sdrug smanufactured sby sdifferent sdrug scompanies scan shave
sdifferent sabsorption srates.
A. sDifferent sdrug scompanies suse sdifferent sactive singredients
B. sDrug scompanies suse sdifferent sfillers sand sbinders s(inactive singredients) sthat
schange sbioavailability
C. sDifferent scompanies suse sdifferent schemical snames sfor sthe ssame sdrug
D. sThe sFDA srequires sdifferent sabsorption srates sfor sgeneric smedications
Answer: sB s– sDrug scompanies suse sdifferent sfillers sand sbinders s(inactive
singredients) sthat schange sbioavailability
Rationale: sThe srate sat swhich sa sdrug sis sabsorbed sis sinfluenced sby sphysical sand
schemical sproperties. sDrug scompanies suse sfillers sand sbinders s(inactive
singredients) sthat schange sthe sbioavailability. sMedications scan sbe schemically
sequivalent sbut sabsorbed sat sdifferent srates s.