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Comprehensive, high-yield 2026 CCRN review guide based on AACN guidelines and common exam topics. I’ve structured it by domain (Adult, Pediatric, Critical Care Concepts, Ethics, Ventilation, and Family-Centered Care) for easy studying. This is designed fo

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CCRN 2024 Exam High-Yield Review 1. Critical Care Nursing Basics Definitions Critical Care Nurse: Specialty nurse providing care for critically ill patients in ICU, CCU, Neuro ICU, step-down units. CCRN Certification: Issued by AACN Eligibility: RN/APRN, 2,000 hours direct care, US-based acute/critical care, pass exam Valid for 3 years; requires education + work in critical care for renewal Critical Care Units Unit Description ICU / ITU Highest level of monitoring and care CCU / Cardiac ICU Critical heart disease patients Neuro ICU Stroke, brain injury, hemorrhage, neurosurgery Step-down Transition from ICU to general ward Step-up For patients deteriorating on wards Intermediate/Transition Between ICU and general floor 2. Patient Monitoring & Equipment Continuous Monitors ECG, arterial pressure, SpO₂ Invasive: arterial, venous, intra-abdominal, intracranial Airway Equipment ET tube, laryngoscope, suction, ventilators, Ambu bag, oxygen delivery Resuscitation Defibrillator, infusion pumps, waveform capnography, pressure bag 3. Critical Thinking & Nursing Competencies Critical thinking: Essential for rapid, safe decision-making Advocacy: Represent patient/family, address concerns Caring attitude: Compassionate, therapeutic, patient-focused Family-centered care: Themes: Enacting care: Care structured around patient & family Connecting: Allow personal connection Remember own experience: Empathy for families Partnering with nurses: Communication is essential Empathy: Active listening, emotional support 4. Patient-Centered Care (PCC) Definition: Multidimensional approach focusing on: Whole person Patient engagement & empowerment Emotional support Alleviating physical discomfort 5. Adult Critical Care Concepts Respiratory Failure & Ventilation Term Meaning / Use PEEP Positive pressure during expiration; opens alveoli SIMV Synchronized intermittent mandatory ventilation; patient can initiate breaths PS Pressure support; patient does all WOB CPAP Continuous positive airway pressure; spontaneous breathing only V/AC Volume assist/control; ventilator does most WOB Complications: Too much PEEP → pneumothorax, decreased cardiac output ARDS Causes: Direct: aspiration, trauma, pneumonia; Indirect: burns, sepsis, transfusions Hallmark: Hypoxemia not responding to O₂ Phases: Acute/exudative (1 wk), Proliferative (1–3 wks), Fibrotic (2–3 wks) Mortality: Often from multi-organ failure Pulmonary Embolism Causes: DVT, venous stasis, hypercoagulable states, vessel injury Signs: Sudden dyspnea, hypoxemia, chest pain, tachycardia, SpO₂ drop Prevention: Heparin/Lovenox, TED hose 6. Pediatric Critical Care Highlights Salicylate toxicity: Replace fluids & electrolytes Chest tube prep (developmental age actual age): Use short, concrete explanations Parental grief with accidental injury: Support parents to support siblings SIADH: Decreased serum osmolality Severe pediatric asthma: Monitor for intubation; early ABG shows respiratory acidosis Digoxin toxicity: Monitor HR, rhythm, perfusion; avoid atropine unless symptomatic bradycardia 7. Ethics & Legal Considerations Autonomy: Respect patient decisions Beneficence: Act in patient’s best interest Nonmaleficence: Avoid harm Justice: Fair allocation of resources Consent: Patient must be competent, voluntary, informed Proxy / Surrogate: Used if patient incompetent End-of-life care: Withholding care → decide not to start life support Withdrawing care → remove life support Euthanasia → actively end life (legally different) Palliative vs Hospice: Palliative → symptom relief alongside treatment Hospice → 6 months life expectancy, comfort care 8. Pain, Anxiety, & Sedation Management SNS activation signs: Diaphoresis, tachycardia, hypertension, dyspnea, flushing Assess before meds: Pain location, severity, characteristics Neuromuscular blockade: Causes chemical paralysis, no analgesia → always sedate first Monitor using Train of Four (TOF) Behavioral Pain Scale (BPS): For intubated patients; 3 = no pain, 12 = max pain This guide covers all critical 2026 CCRN topics and aligns with AACN standards for adult, pediatric, and ethics care.

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AACN Critical Care Registered
Nurse (CCRN) 2024 Exam
Review Questions and Answers
100% Pass

A 56 yr-old male is admitted to the ICU with a blood
pressure of 225/135 and complains of a headache and
nausea. He reports he ran out of blood pressure meds
three days ago, but also appears to be confused to the
date and situation. What is the most appropriate
treatment approach?
- Answer>> Rapidly lower the diastolic pressure to 100
with IV antihypertensive meds, then continue to
gradually reduce the diastolic pressure to 85 with oral
antihypertensive meds.


The maximum initial decrease should be no more than
25% reduction from initial presenting value. Reducing
the blood pressure too quickly can lead to cerebral
edema or renal failure.

,A patient has sepsis, receives Lactated ringers 500ml IV
bolus. Which finding indicate that this intervention is
having it's intended effect?
- Answer>> ScvO2 of 72%


Early goal directed therapy for sepsis includes early fluid
resuscitation at 30 ml/kg to maintain a CVP of 8-12 or
12-15 if mechanically ventilated, MAP greater than 65,
ScvO2 greater than 70%, and urine output greater than
0.5 kg/hr


72 male patient in ICU for 6 days on the ventilator for
treatment of a COPD exacerbation. He has been receiving
VTE prophylaxis and subcutaneous Heparin since
admission. Today his platelet count decreased
significantly to 43,000 and was found to have new DVT
on his right upper extremity. What do you suspect is the
most likely cause of these findings?
- Answer>> HIT


The hallmark sign of HIT is a significant decrease in
platelet count over a 24 hours period (>50%) within 5-10

,days of administering Heparin. The other hallmark sign
is a new development of DVT despite being on VTE
prophylaxis.


TRALI:
- Answer>> is a complication from a blood transfusion
reaction, which causes acute lung injury typically within
6 hours of a blood transfusion.


2 Hallmark signs of HIT:
- Answer>> Decrease in platelet count over a 24 hr
period.


New development of DVT despite being on VTE
prophylaxis.


Values in Early compensated Hypovolemic shock?
- Answer>> CO 4.0 L/min, HR 135, SV 65, SVR 1700, MAP
65
In hypovolemic states, circulating volume is depleted
therefore preload and contractility are decreased which
leads to a decrease in SV and CO. HR and SV increase as

, compensatory measure to preserve CO, MAP and cerebral
perfusion.


Post-renal failure values:
- Answer>> Urine output < 200; urine sodium 30; BUN:
Creatinine ratio 15:1; urine specific gravity 1.010


BUN: Creatinine ratio is 15:1, but both the BUN &
creatinine are elevated. Urine sodium is typically 1-40
mEq/L.


What to do in the event of HIT:
- Answer>> Stop Heparin and administer an alternative
direct thrombin inhibitor.


Warfarin is contraindicated in HIT? T/F
- Answer>> True - there is also no evidence that shows
protamine, corticosteroids, and benadryl are effective
treatments for HIT


Patients with right ventricular infarctions become
preload dependent. Meds that decrease preload should

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