Review Pack covering Genetics,
Molecular Biology, and Evolution for
the 2026/2027 syllabus.
Section 1: Mendelian & Population Genetics (Q1–30)
Q1 In a monohybrid cross between two heterozygous pea plants (Aa × Aa), what
proportion of offspring will be homozygous dominant?
ANSWER ✓
Q2 What is the probability that two heterozygous parents (Aa × Aa) produce a child
with the recessive phenotype?
ANSWER ✓
Q3 In a dihybrid cross (AaBb × AaBb), assuming independent assortment, what fraction
of offspring will be A_bb?
ANSWER ✓
Q4 A man with blood type AB marries a woman with type O. What is the probability
their child has type A blood?
ANSWER ✓
Q5 What is the term for a gene that masks the expression of another gene at a different
locus?
ANSWER ✓
Q6 In X-linked recessive disorders, which gender is more likely to be affected?
ANSWER ✓
Q7 A colorblind father (XᶜY) and a carrier mother (XᶜX) have a daughter. What is the
chance she is colorblind?
ANSWER ✓
, Q8 What is the Hardy-Weinberg equation for genotype frequencies?
ANSWER ✓
Q9 In a population in HWE, if frequency of recessive allele (q) = 0.3, what is frequency of
heterozygotes?
ANSWER ✓
Q10 What evolutionary force reduces genetic variation by random chance, especially in
small populations?
ANSWER ✓
Q11 What does the term "fitness" mean in evolutionary genetics?
ANSWER ✓
Q12 If a population has genotype frequencies AA=0.36, Aa=0.48, aa=0.16, is it in Hardy-
Weinberg equilibrium?
ANSWER ✓
Q13 What is the difference between directional and stabilizing selection?
ANSWER ✓
Q14 What is the coefficient of relatedness (r) between full siblings?
ANSWER ✓
Q15 What is the name of the phenomenon where heterozygotes have higher fitness
than either homozygote?
ANSWER ✓
Q16 In a test cross (AaBb × aabb), what ratio indicates independent assortment?
ANSWER ✓
Q17 What is linkage disequilibrium?
ANSWER ✓
Q18 A woman is a carrier for hemophilia (XᴴXʰ). She has a child with a normal man (XᴴY).
What % of sons will have hemophilia?
ANSWER ✓
Q19 What is pleiotropy?
ANSWER ✓
Q20 What is the term for when one gene locus affects expression of another?
ANSWER ✓