m m m m m m m m m
3rd Edition by M. Linda Workman & LaCharit
m
m m m m m m
y
,Chapterm01:mDrugmRegulation,mActions,mandmResponses
Workmanm&mLaCharity:mUnderstandingmPharmacology:mEssentialsmformMedicationmSafety,m3rdmEdit
ion
MULTIPLEmCHOICEmBASICm CON
CEPTS
1. Whichmhealthmcaremprofessionalmhasmthemmajormresponsibilitymformdispensingmpres
cribedm drugsmundermthemdirectionmofmampharmacist?
a. Physician
b Nursempractitioner
.
c. Licensedmnurse
d Pharmacymtechnicia
. n
ANS:mm D
Themphysicianmandmnursempractitionermhavemthemmajormresponsibilitymformprescribingmdrugs,mnot
m dispensingmthem.mThemlicensedmnursemhasmthemprimarymresponsibilitymformadministeringmdrugs,
m althoughmundermsomemcircumstancesmamlicensedmnursemmaymdispensemprescribedmdrugsmbutmthis
mismnotm hismormhermmajormresponsibilityminmdrugmtherapy.mThempharmacymtechnicianmhasmthemmaj
orm responsibilitymofmdispensingmprescribedmdrugsmundermthemdirectionmofmamlicensedmpharmacist
.
DIF: CognitivemLevel:mRemembering REF: p.m3
2. Whichmtermmdescribesmthemeffectmofmamdrugmthatmimprovesmbodymfunction?
a. Sidemeffect
b Intendedmactio
. n
c. Adversemreaction
d Idiosyncraticmresponse
.
ANS:mm B
Thempurposemofmdrugmtherapymismtomtakemamdrugmtomprevent,mreduce,mormcorrectmamhealthmproble
m.mThis
responsemismanymdrug’smintendedmactionmalsomknownmasmamtherapeuticmresponse.
DIF: CognitivemLevel:mRemembering REF: p.m3
3. Whichmtypemofmdrugmnamemism“owned”mbymthemcompanymthatmmanufacturesmit?
a. Genericmname
b Chemicalmname
,.
c. Categorymname
d Trademnam
. e
ANS:mm D
Themchemicalmnamemismamdrug’smexactmchemicalmcomposition.mThemgenericmnamemismthemnamemassi
gnedmtom themdrugmbymthemU.S.mAdoptedmNamesmCouncilmandmismnotmownedmbymanyone.mThemcat
egorymnamemrefersm tomthemtypemofmdrugm(whatmitmdoesmormwhatmitmismusedmfor)mandmismnotmanmac
tualmdrugmname.mThemtradem namem(brandmname)mismthemnamemprovidedmandmownedmbymamspeci
ficmdrug’smmanufacturer.
DIF: CognitivemLevel:mRemembering REF: p.m4
4. Whichmdrugmormdrugmclassmismam“highmalert”m
a. Penicillin
drug?
b Insulin
.
c. NSAIDs
d Calcium
.
ANS:mm B
Amhighmalertmdrugmismoneminmwhichmharmmismlikelymtomresultmifmgivenmatmthemwrongmdose,mtomthemw
rongm patient,mormnotmgivenmtomthemcorrectmpatient.mDrugsmclassifiedmasmhighmalertmdrugsmincludem
potassium,m narcoticsm(opioids),minsulin,mcancermchemotherapymdrugs,mandmheparinm(ormanymdrugm
thatmstronglym affectsmbloodmclotting).mPenicillin,mNSAIDs,mandmcalciummaremnotmconsideredmhighm
alertmdrugs.
DIF: CognitivemLevel:mRemembering REF: p.m4
5. Whatmismthemtermmformamdrugmthatmhasmthemsamemactionmasmamnaturallymoccurri
ngmbodym hormonemormenzyme?
a. Agonis
b Blocking
t magent
.
c. Chemical
d Duplicator
.
ANS:mm A
Amdrugmagonistmismanmextrinsicmdrugmthatmactivatesmthemreceptormsitesmofmamcellmandmmimicsmthemact
ionsmofm naturallymoccurringmbodymsubstancesm(intrinsicmdrugs).mAmblockingmagentmismamdrug
, antagonist.mAmchemicalmwouldmnotmnecessarilymbemamdrugmatmall.mAmduplicatormismnotmampharmacol
ogicmterm.m DIF: CognitivemLevel:mRemembering REF: pp.m6-
7
6. Whichmtermmdescribesmhowmthembodymaffectsmdrugmactivity?
a. Drugmpotency
b Pharmacodynamics
.
c. Therapeuticmeffect
d Pharmacokinetics
.
ANS:mm D
Themtermmpharmacokineticsmrefersmtomdrugmmetabolismmandmhowmthembodymchangesmamdrug.m Ph
armacodynamicsmrefersmtomhowmamdrugmworksmtomchangembodymfunction.mDrugmpotencymrefersmto
mhowm stronglymormtomwhatmdegreemamdrugmexertsmitsmeffects.mThemtherapeuticmeffectmismclosermto
m pharmacodynamics,mmeaningmhowmamdrugmworksmtomchangembodymfunction.
DIF: CognitivemLevel:mRemembering REF: p.m10
7. InmthemUnitedmStates,mwhichmgroupmismresponsiblemformenforcingmestablishedmstandar
dsmform drugmmanufacturing?
a. U.S.mPharmacopeia
b NationalmInstitutesmofmHealth
.
c. FoodmandmDrugmAdministratio
d Association
n mofmPharmaceuticalmManufacturers
.
ANS:mm C
Them standardsm formdrugm manufacturem arem establishedmbym them U.S.mPharmacopeia.mThesem stand
ardsm arem enforcedm bym them Foodm andm Drugm Administration.m Neitherm them Nationalm Institutesm of
m Healthm norm them AssociationmofmPharmaceuticalmManufacturersmhasmanymauthoritymtomenforcemdr
ugmstandards.
DIF:mmmm CognitivemLevel:mRememberingmmmmmmmmm REF:mmm p.m5
8. Whichmfactormismammajormdisadvantagemofmthemtransdermalmdrugmdeliverymroute?
a. Onlymamprescribermcanmadministermdrugsmbymthemtransdermalmrout
b e.
Transdermalmdrugsmmustmbemsterilemrathermthanmclean.
.
c. Firstmpassmdrugmlossmbymthismroutemismthemmostmextensive.
d Drugmabsorptionmismdependentmonmadequatemcircula
tion.