NAMs Menopause Certification Exam 2026/2027 ||
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difference between menopause transition vs
perimenopause per STRAW criteria? - Answer-
menopause transition: -2 and -1, prior to FMP
perimenopause: -2 to +1a, includes 12 mo of amenorrhea
following FMP
which STRAW stage?
initial drop in AMH/AFC/inhibin, cycles still regular, FSH
normal - Answer--3b
aka late reproductive
which STRAW stage?
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cycles shorter, first increase in FSH - Answer--3a
aka late reproductive
levels spike with ovulation, marker of ovarian reserve -
Answer-inhibin B
Produced by granulosa cells of activated follicles, most
reflective of true ovarian reserve; provides the best single
prediction of time to menopause - Answer-AMH
what day of cycle to draw FSH to predict ovarian
response/reserve? - Answer-day 3
normal day 3 FSH?
FSH value for menopause? - Answer-< 10
>25
# of ultrasound detected follicles 2-10 mm in size -
Answer-AFC (antral follicle count)
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normal AFC - Answer->12
Luteal-Out-Of-Phase (LOOP) event - Answer-- FSH
elevation recruits follicles for the subsequent cycle before
the current cycle is over
- Excess estradiol production as new follicles start growing
- Increase chance of TWINS
- Very short follicular phase
- More time spent in luteal phase (more PMS/PMDD sx)
symptoms of LOOP event - Answer-—Mastalgia
—Worsening migraine
—Growing fibroids
—Risk of endometrial hyperplasia
- longer time in luteal phase (worsening PMDD in peri)
premenopausal vs postmenopausal estradiol levels in
obesity - Answer-pre: lower, more anovulatory cycles
post: higher
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consequence of inhibin B and AMH drop in early
menopause transition? - Answer-FSH spikes --> fast
growth of remaining follicles (twins more likely) --> shorter
follicular phase --> follicle atresia --> LOOP cycles -->
pronounced PMS sx from longer luteal phase --> cycle
irregularity by >7 days
dec ovarian reserve causes the drop in what 2 hormones?
- Answer-inhibin B and AMH
4 adrenal androgens - Answer-—Dehydroepiandrosterone
(DHEA)
—Dehydroepiandrosterone sulfate (DHEAS)
—Androstenedione
—Testosterone
where are adrenal androgens converted to estrogen? -
Answer-peripheral tissue
what happens to DHEA levels during menopause
transition? - Answer-transient increase then return to
premenopause baseline