university Diagnostic Evaluation, Differential Diagnosis,
and Evidence-Based Management of a 33-Year-Old Female
with Flank Pain
1. Title Page
Student Name: [Your Name]
Institution: Walden University
Course: NRNP 6512 Advanced Health Assessment
Assignment: Week 7 i-Human Case Study
Date: [Insert Date]
2. Abstract
, Flank pain in adult females presents a broad diagnostic challenge requiring careful differentiation
between genitourinary, musculoskeletal, and gastrointestinal etiologies. This case study
examines a 33-year-old female presenting with acute flank pain, emphasizing a systematic
approach to history-taking, physical examination, diagnostic reasoning, and evidence-based
management. The clinical findings support a primary diagnosis of acute pyelonephritis with
differential considerations including nephrolithiasis and musculoskeletal strain. Evidence-based
interventions, pharmacologic therapy, patient education, and follow-up care are discussed in
alignment with current clinical guidelines.
3. Chief Complaint (CC)
“I have pain on my right side of my back that started yesterday and is getting worse.”
4. History of Present Illness (HPI)
The patient is a 33-year-old female presenting with acute onset right-sided flank pain that
began approximately 24 hours prior to evaluation. The pain is described as:
• Location: Right flank, radiating toward the abdomen
• Onset: Sudden
• Duration: Persistent for 24 hours
• Character: Sharp and constant
• Severity: 7/10
• Radiation: Toward lower abdomen
• Aggravating factors: Movement, palpation
• Relieving factors: Minimal relief with OTC analgesics
• Associated symptoms:
o Fever and chills
o Nausea
o Dysuria
o Urinary frequency
The patient denies trauma, hematuria (initially), or recent strenuous activity.
5. Past Medical History (PMH)
• Recurrent urinary tract infections (UTIs)
• No history of kidney stones
• No chronic illnesses (e.g., diabetes, hypertension)