4/8/26, 6:06 PM WGU D116 Pharmacology review COMPREHENSIVE QUESTIONS AND VERIFIED ANSWERS (DETAILED & ELABORATED) ACT…
WGU D116 Pharmacology review COMPREHENSIVE
QUESTIONS AND VERIFIED ANSWERS (DETAILED &
ELABORATED) ACTUAL EXAM 2026 TEST 100% SOLVED !!
A patient presents to an emergency room complaining of palpitations and
irregular heartbeat. The advanced practice registered nurse (APRN) places
the patient on a cardiac monitor and observes atrial fibrillation. The APRN
orders dofetilide.
How should the APRN recommend this medication be taken?
YES With food or an empty stomach
A 70-year-old male calls a clinic complaining of chest pain that started after
having sexual activity. He took sildenafil 50 mg about eight hours ago. He has
nitroglycerin
0.3 mg on hand.
How should the advanced practice registered nurse respond?
Do not take the nitroglycerin and call 911
Taking the medications together can cause a serious drop in blood pressure
leading to cardiovascular collapse.
… 1/85
,4/8/26, 6:06 PM WGU D116 Pharmacology review COMPREHENSIVE QUESTIONS AND VERIFIED ANSWERS (DETAILED & ELABORATED) ACT…
A patient diagnosed with bipolar disorder who is in a mental health clinic is
discussing the possibility of beginning lithium with an advanced practice
registered nurse (APRN). The patient expresses understanding and
wishes to proceed with
treatment. The APRN explains to the patient that this medication requires
specific lab monitoring and wants to draw baseline labs. The patient asks
why the test is needed. Which explanation should the APRN provide to
this patient?
A baseline blood urea nitrogen (BUN) and creatinine (CREA) level needs
to be drawn to assess kidney function prior to treatment.
This drug can cause decreased renal function, and a baseline should be drawn
for future comparison.
An advanced practice registered nurse (APRN) is reviewing the
medications that will be commonly experienced with a new nurse to
determine whether the drugs are
safe for the patients. The new nurse is given a scenario where a patient is
being prescribed sildenafil 25 mg po prn, a prototype drug for erectile
dysfunction. Which patient may take this drug safely?
YES A 54-year-male with a medical history of hypertension, mild eczema, and
previous history of a urolithiasis where all is well controlled and there are no
current complications
… 2/85
,4/8/26, 6:06 PM WGU D116 Pharmacology review COMPREHENSIVE QUESTIONS AND VERIFIED ANSWERS (DETAILED & ELABORATED) ACT…
A 30-year-old patient presents to a primary care clinic with a history of
anxiety. The advanced practice registered nurse reviews the mechanism of
action by which many neuropharmacological agents act and decides to
prescribe citalopram.
What is the mechanism of action of this medication?
YES Influences receptor activity on target cells
Correct! This medication influences the activity in the receptors, and it targets
cells.
A patient has been taking oral oxycodone every six hours for back pain during
the past three years. The patient suddenly decides to stop taking the pain
medication and is trying an alternative therapy without a clinician's approval.
Which risk is of clinical concern?
YES Physical dependence
Correct! The patient suddenly stopping the medication will cause physical
symptoms that can range from nausea to seizures.
… 3/85
, 4/8/26, 6:06 PM WGU D116 Pharmacology review COMPREHENSIVE QUESTIONS AND VERIFIED ANSWERS (DETAILED & ELABORATED) ACT…
A patient is admitted with a diagnosis of Huntington disease. On admission,
the patient exhibits uncontrolled twitching, difficulty walking, trouble
swallowing, confusion, and memory loss. The advanced practice registered
nurse (APRN) prescribes baclofen.
What is the mechanism of action of this medication?
NO Modulates the effects of glutamate at NMDA
receptors YES Inhibits neurotransmitter GABA
NO Halts the breakdown of acetylcholine by acetylcholinesterase
Alters the synthesis and release of norepinephrine, serotonin, and dopamine
Incorrect. Cholinesterase inhibitors prevent the breakdown of acetylcholine
by acetylcholinesterase. They are used in patients with Alzheimer's.
Correct! Huntington's disease involves a deficiency of the
neurotransmitters acetylcholine and y-aminobutyric acid in the basal
ganglia and extrapyramidal system.
A 21-year-old patient accompanied by a parent comes to a clinic for an
emergency visit with an advanced practice registered nurse (APRN)
following a seizure. Upon
interviewing the patient and the parent, the APRN determines that the
seizure is classified by marked impairment of consciousness and is
followed by a period of central nervous system (CNS) depression.
Which type of seizure is this patient experiencing?
Atonic
NO Myoclonic
YES Tonic-
clonic Absence
Incorrect. Myoclonic seizures consist of a sudden muscle contraction that
lasts for just one second.
Correct! A tonic-clonic seizure is a type of seizure that is also called a
convulsion. This type of seizure can include muscle stiffness, loss of
consciousness, and body jerking.
… 4/85
WGU D116 Pharmacology review COMPREHENSIVE
QUESTIONS AND VERIFIED ANSWERS (DETAILED &
ELABORATED) ACTUAL EXAM 2026 TEST 100% SOLVED !!
A patient presents to an emergency room complaining of palpitations and
irregular heartbeat. The advanced practice registered nurse (APRN) places
the patient on a cardiac monitor and observes atrial fibrillation. The APRN
orders dofetilide.
How should the APRN recommend this medication be taken?
YES With food or an empty stomach
A 70-year-old male calls a clinic complaining of chest pain that started after
having sexual activity. He took sildenafil 50 mg about eight hours ago. He has
nitroglycerin
0.3 mg on hand.
How should the advanced practice registered nurse respond?
Do not take the nitroglycerin and call 911
Taking the medications together can cause a serious drop in blood pressure
leading to cardiovascular collapse.
… 1/85
,4/8/26, 6:06 PM WGU D116 Pharmacology review COMPREHENSIVE QUESTIONS AND VERIFIED ANSWERS (DETAILED & ELABORATED) ACT…
A patient diagnosed with bipolar disorder who is in a mental health clinic is
discussing the possibility of beginning lithium with an advanced practice
registered nurse (APRN). The patient expresses understanding and
wishes to proceed with
treatment. The APRN explains to the patient that this medication requires
specific lab monitoring and wants to draw baseline labs. The patient asks
why the test is needed. Which explanation should the APRN provide to
this patient?
A baseline blood urea nitrogen (BUN) and creatinine (CREA) level needs
to be drawn to assess kidney function prior to treatment.
This drug can cause decreased renal function, and a baseline should be drawn
for future comparison.
An advanced practice registered nurse (APRN) is reviewing the
medications that will be commonly experienced with a new nurse to
determine whether the drugs are
safe for the patients. The new nurse is given a scenario where a patient is
being prescribed sildenafil 25 mg po prn, a prototype drug for erectile
dysfunction. Which patient may take this drug safely?
YES A 54-year-male with a medical history of hypertension, mild eczema, and
previous history of a urolithiasis where all is well controlled and there are no
current complications
… 2/85
,4/8/26, 6:06 PM WGU D116 Pharmacology review COMPREHENSIVE QUESTIONS AND VERIFIED ANSWERS (DETAILED & ELABORATED) ACT…
A 30-year-old patient presents to a primary care clinic with a history of
anxiety. The advanced practice registered nurse reviews the mechanism of
action by which many neuropharmacological agents act and decides to
prescribe citalopram.
What is the mechanism of action of this medication?
YES Influences receptor activity on target cells
Correct! This medication influences the activity in the receptors, and it targets
cells.
A patient has been taking oral oxycodone every six hours for back pain during
the past three years. The patient suddenly decides to stop taking the pain
medication and is trying an alternative therapy without a clinician's approval.
Which risk is of clinical concern?
YES Physical dependence
Correct! The patient suddenly stopping the medication will cause physical
symptoms that can range from nausea to seizures.
… 3/85
, 4/8/26, 6:06 PM WGU D116 Pharmacology review COMPREHENSIVE QUESTIONS AND VERIFIED ANSWERS (DETAILED & ELABORATED) ACT…
A patient is admitted with a diagnosis of Huntington disease. On admission,
the patient exhibits uncontrolled twitching, difficulty walking, trouble
swallowing, confusion, and memory loss. The advanced practice registered
nurse (APRN) prescribes baclofen.
What is the mechanism of action of this medication?
NO Modulates the effects of glutamate at NMDA
receptors YES Inhibits neurotransmitter GABA
NO Halts the breakdown of acetylcholine by acetylcholinesterase
Alters the synthesis and release of norepinephrine, serotonin, and dopamine
Incorrect. Cholinesterase inhibitors prevent the breakdown of acetylcholine
by acetylcholinesterase. They are used in patients with Alzheimer's.
Correct! Huntington's disease involves a deficiency of the
neurotransmitters acetylcholine and y-aminobutyric acid in the basal
ganglia and extrapyramidal system.
A 21-year-old patient accompanied by a parent comes to a clinic for an
emergency visit with an advanced practice registered nurse (APRN)
following a seizure. Upon
interviewing the patient and the parent, the APRN determines that the
seizure is classified by marked impairment of consciousness and is
followed by a period of central nervous system (CNS) depression.
Which type of seizure is this patient experiencing?
Atonic
NO Myoclonic
YES Tonic-
clonic Absence
Incorrect. Myoclonic seizures consist of a sudden muscle contraction that
lasts for just one second.
Correct! A tonic-clonic seizure is a type of seizure that is also called a
convulsion. This type of seizure can include muscle stiffness, loss of
consciousness, and body jerking.
… 4/85
