PATH 3610: ALL TESTS - QUESTIONS AND ANSWERS |
2026 UPDATE | WITH COMPLETE SOLUTION.
The release of cytoplasmic enzymes from necrotic cells may be useful
diagnostically.
a. True
b. False Answer - True
Bilirubin is:
a. Lipid soluble when conjugated
b. Water soluble when conjugated
c. Conjugated in the kidney for excretion in the urine Answer - Water soluble
when conjugated
Agents such as radiation, mutagenic drugs and viruses can lead to acquired
DNA abnormalities. Damage to cells such as blood cell precursors in the bone
marrow is the result of:
a. Failed synthesis of structural proteins
b. Failure of growth regulating proteins
c. Interference with mitosis Answer - a. Interference with mitosis
Free radicals can impair cell membrane function by causing:
a. Lesions in DNA
,b. Lipid peroxidation
c. Protein cross-linking Answer - a. Lipid peroxidation
Anemia will lead to impaired energy production by the cell because there is:
a. Insufficient oxygen
b. Low glucose levels
c. Enzyme inhibition Answer - Insufficient oxygen
The primary change in hemolytic jaundice is:
a. Inadequate bilirubin excretion
b. Increased production of bilirubin
c. Serum accumulation of conjugated bilirubin Answer - Increased production
of bilirubin
Triglyceride accumulation in the cytoplasm of parenchymal cells (such as the
liver) is termed:
a. Cytoplasm vacuolation
b. Hyperglycemia
c. Fatty degeneration Answer - Fatty degeneration
Hypoxia, leading to impaired energy production by the cell, may be caused by:
a. Anemia
b. Low blood glucose levels
c. Inhibition of respiratory enzymes Answer - Anemia
Death of cells in a living organism is termed:
a. Gangrene
,b. Necrosis
c. Ischemia Answer - Necrosis
Starvation can lead to the development of fatty liver.
a. True
b. False Answer - True
Cloudy swelling is the result of:
a. Intracellular accumulation of fluid and electrolytes
b. Decreased intracellular pH
c. Triglyceride accumulation Answer - Intracellular accumulation of fluid and
electrolytes
The most definitive microscopic evidence of cell necrosis is:
a. Homogenous, more deeply staining cytoplasm
b. Cytoplasmic vacuolation
c. Nuclear pyknosis and karrhyorhexis Answer - a. Nuclear pyknosis and
karrhyorhexis
Chronic over-consumption of alcohol can lead to fatty liver due to:
a. Decreased oxidation of triglycerides
b. Increased activity of hepatic enzyme systems, leading to increased
conversion of fatty acids to triglycerides
c. Decreased mobilization of adipose tissue due to decreased alcoholic caloric
consumption Answer - Increased activity of hepatic enzyme systems, leading
to increased conversion of fatty acids to triglycerides
The colour changes in a bruise are related to:
, a. Necrosis of tissue
b. Synthesis of hemoglobin
c. Breakdown of hemoglobin Answer - Breakdown of hemoglobin
Dystrophic calcification refers to abnormal deposition of calcium salts:
a. In dead or dying tissues
b. In tissues due to high serum calcium levels
c. Associated with inherited calcium metabolic disorders Answer - In dead or
dying tissues
Cellular injury can result when bilirubin accumulates in:
a. Parenchymal cells (such as the liver or brain)
b. Connective tissue
c. Skin Answer - Parenchymal cells (such as the liver or brain)
A myocardial infarct is seen as a dry, well demarcated area of pale tissue. This
would be described as:
a. Coagulation necrosis
b. Caseation necrosis
c. An abscess Answer - Coagulation necrosis
Local death of a cell or cells due to injury is known as:
a. Ischemia
b. Necrosis
c. Infarction Answer - Necrosis
Swelling of mitochondria caused by impaired cell energy production can cause:
2026 UPDATE | WITH COMPLETE SOLUTION.
The release of cytoplasmic enzymes from necrotic cells may be useful
diagnostically.
a. True
b. False Answer - True
Bilirubin is:
a. Lipid soluble when conjugated
b. Water soluble when conjugated
c. Conjugated in the kidney for excretion in the urine Answer - Water soluble
when conjugated
Agents such as radiation, mutagenic drugs and viruses can lead to acquired
DNA abnormalities. Damage to cells such as blood cell precursors in the bone
marrow is the result of:
a. Failed synthesis of structural proteins
b. Failure of growth regulating proteins
c. Interference with mitosis Answer - a. Interference with mitosis
Free radicals can impair cell membrane function by causing:
a. Lesions in DNA
,b. Lipid peroxidation
c. Protein cross-linking Answer - a. Lipid peroxidation
Anemia will lead to impaired energy production by the cell because there is:
a. Insufficient oxygen
b. Low glucose levels
c. Enzyme inhibition Answer - Insufficient oxygen
The primary change in hemolytic jaundice is:
a. Inadequate bilirubin excretion
b. Increased production of bilirubin
c. Serum accumulation of conjugated bilirubin Answer - Increased production
of bilirubin
Triglyceride accumulation in the cytoplasm of parenchymal cells (such as the
liver) is termed:
a. Cytoplasm vacuolation
b. Hyperglycemia
c. Fatty degeneration Answer - Fatty degeneration
Hypoxia, leading to impaired energy production by the cell, may be caused by:
a. Anemia
b. Low blood glucose levels
c. Inhibition of respiratory enzymes Answer - Anemia
Death of cells in a living organism is termed:
a. Gangrene
,b. Necrosis
c. Ischemia Answer - Necrosis
Starvation can lead to the development of fatty liver.
a. True
b. False Answer - True
Cloudy swelling is the result of:
a. Intracellular accumulation of fluid and electrolytes
b. Decreased intracellular pH
c. Triglyceride accumulation Answer - Intracellular accumulation of fluid and
electrolytes
The most definitive microscopic evidence of cell necrosis is:
a. Homogenous, more deeply staining cytoplasm
b. Cytoplasmic vacuolation
c. Nuclear pyknosis and karrhyorhexis Answer - a. Nuclear pyknosis and
karrhyorhexis
Chronic over-consumption of alcohol can lead to fatty liver due to:
a. Decreased oxidation of triglycerides
b. Increased activity of hepatic enzyme systems, leading to increased
conversion of fatty acids to triglycerides
c. Decreased mobilization of adipose tissue due to decreased alcoholic caloric
consumption Answer - Increased activity of hepatic enzyme systems, leading
to increased conversion of fatty acids to triglycerides
The colour changes in a bruise are related to:
, a. Necrosis of tissue
b. Synthesis of hemoglobin
c. Breakdown of hemoglobin Answer - Breakdown of hemoglobin
Dystrophic calcification refers to abnormal deposition of calcium salts:
a. In dead or dying tissues
b. In tissues due to high serum calcium levels
c. Associated with inherited calcium metabolic disorders Answer - In dead or
dying tissues
Cellular injury can result when bilirubin accumulates in:
a. Parenchymal cells (such as the liver or brain)
b. Connective tissue
c. Skin Answer - Parenchymal cells (such as the liver or brain)
A myocardial infarct is seen as a dry, well demarcated area of pale tissue. This
would be described as:
a. Coagulation necrosis
b. Caseation necrosis
c. An abscess Answer - Coagulation necrosis
Local death of a cell or cells due to injury is known as:
a. Ischemia
b. Necrosis
c. Infarction Answer - Necrosis
Swelling of mitochondria caused by impaired cell energy production can cause:
