1 SCT 2022
st
Single choice:
1. What is not a substrate for the M-phase CDK: Ciblin B-cdb1
A. Lamins P
B. H1 P
C. H4 P
D. Cdk4
E. Microtubules P
2. Which of the following is the cause of Rubinstein-Taybi
syndrome?
A. 53
B. CPB
C. Genomic imprinting
D. D. FMR-1
E. CREB
3. What is not CDKI
A. P21 (Ras)
B. p 57 Wee1
kináz
p27
C. P16 T
P
-
P
D. P15 cdc25
E. P27
4. Which protein cannot be directly regulated by cAMP?
A. Epac (a GEF protein)
B. Cl channels in certain type of cells
X -
CFTR
X
C. Na channels in certain type of cells Bear
+ said
*D. CREBP
E. PKA
, 5. Choose the correct sentence regarding siRNAs
A.
X Binding of siRNA activates mRNA silencing by translation
inhibition
B. Binding of siRNA activates protein translation
X
C. Binding of siRNA activates mRNA degradation by
nucleases
D. Binding of siRNA to mRNA is not a 100% match
*E. Binding of siRNA activates X chromosomal-inactivation
6. Which of the following is a stable state in cell cycle?
A. Anaphase
B. Metaphase
C. Late S phase
D. Early G1
E. Prophase
7. What is true about p53?
~A. Most common mutation in cancer is associated with the N-
terminal domain
B. Active P53 causes synthesis of cyclin-D
X
C. In normal cells it is degraded rapidly
X
D.
X Mdm2 stabilizes it No
E. Phosphorylation in the C-terminal domain (CTD) inhibits
↑
binding of Mdm2
8. Which TF is located in the nucleus in the inactive form?
A. Glucocorticoid receptor cytoplasma
X
B. RAR receptor
C. NFκB Cytoplasma
D. Smad cytoplasma
E. Heat-shock proteins minderbol vanual,
ok faltande
a transbripcios
de ma
hamm as HSF-ee .
IRP
(iron response proteins)
9. What is true about cytosolic aconitase and IREs
L
X
A. CRE bound aconitase to 5' mRNA untranslated region
st
Single choice:
1. What is not a substrate for the M-phase CDK: Ciblin B-cdb1
A. Lamins P
B. H1 P
C. H4 P
D. Cdk4
E. Microtubules P
2. Which of the following is the cause of Rubinstein-Taybi
syndrome?
A. 53
B. CPB
C. Genomic imprinting
D. D. FMR-1
E. CREB
3. What is not CDKI
A. P21 (Ras)
B. p 57 Wee1
kináz
p27
C. P16 T
P
-
P
D. P15 cdc25
E. P27
4. Which protein cannot be directly regulated by cAMP?
A. Epac (a GEF protein)
B. Cl channels in certain type of cells
X -
CFTR
X
C. Na channels in certain type of cells Bear
+ said
*D. CREBP
E. PKA
, 5. Choose the correct sentence regarding siRNAs
A.
X Binding of siRNA activates mRNA silencing by translation
inhibition
B. Binding of siRNA activates protein translation
X
C. Binding of siRNA activates mRNA degradation by
nucleases
D. Binding of siRNA to mRNA is not a 100% match
*E. Binding of siRNA activates X chromosomal-inactivation
6. Which of the following is a stable state in cell cycle?
A. Anaphase
B. Metaphase
C. Late S phase
D. Early G1
E. Prophase
7. What is true about p53?
~A. Most common mutation in cancer is associated with the N-
terminal domain
B. Active P53 causes synthesis of cyclin-D
X
C. In normal cells it is degraded rapidly
X
D.
X Mdm2 stabilizes it No
E. Phosphorylation in the C-terminal domain (CTD) inhibits
↑
binding of Mdm2
8. Which TF is located in the nucleus in the inactive form?
A. Glucocorticoid receptor cytoplasma
X
B. RAR receptor
C. NFκB Cytoplasma
D. Smad cytoplasma
E. Heat-shock proteins minderbol vanual,
ok faltande
a transbripcios
de ma
hamm as HSF-ee .
IRP
(iron response proteins)
9. What is true about cytosolic aconitase and IREs
L
X
A. CRE bound aconitase to 5' mRNA untranslated region
