NURS 6630 PSYCHOPHARMACOLOGY
ACTUAL COMPLETE FINAL EXAM 2026
QUESTIONS AND CORRECT ANSWERS
(100% CORRECT VERIFIED ANSWERS)
postsysnaptic 5HT2 receptors - Anwser//SSRIs First line therapy
for MDD due to milder side effect profiles - Anwser//SSRIs Six
Common SSRIs - Anwser//citalopram, escitalopram, fluoxetine,
fluvoxamine, sertraline, paroxetine Onset of therapeutic
benefit from SSRIs - Anwser//4-6 weeks In addition to MDD,
SSRIs also treat - Anwser//Chronic Anxiety, PTSD, OCD, and
eating disorders (bulimia) Five Common side effects of SSRIs
include - Anwser//Anxiety, insomnia, GI distress, sexual
dysfunction (ED), SIADH Severe side effect of SSRIs in
children/adolescents under age 25 years old - Anwser//suicidal
ideation Life threatening adverse effect of SSRIs, especially
when used in combination with other serotonergic drugs (SNRIs,
TCAs, MAOIs, etc.) - Anwser//Serotonin Syndrome Excess
accumulation of serotonin resulting in overstimulation of the
nervous system - Anwser//Serotonin Syndrome Seven
symptoms of Serotonin Syndrome - Anwser//Flushing,
hyperthermia, agitation, muscle rigidity, seizure, coma,
HYPERreflexia The treatment for serotonin syndrome -
Anwser//Cyproheptadine (5-HT2 receptor antagonist)
Cyproheptadine treats serotonin syndrome by -
Anwser//blocking 5-HT2 receptors (serotonin antagonist) When
SSRIs or SNRIs are stopped abruptly, common symptoms of
withdrawal include - Anwser//Irritability, headaches, and
insomnia Medicine specific side effect of citalopram -
Anwser//Prolonged QT interval (normal=0.4.-0.44 seconds) This
SSRI is pregnancy category D due to associations with
congenital heart defects - Anwser//Paroxetine All SSRIs but
,paroxetine (D) are pregnancy category - Anwser//C Three SSRIs
that are inhibitors of Cytochrome P450 enzymes -
Anwser//fluoxetine, fluvoxamine, and paroxetine Five common
SNRIs include - Anwser//duloxetine, venlafaxine,
desvenlafaxine, milnacipran, levomilnacipran This
antidepressant class of medications works by binding to
presynaptic SERT and NET to inhibit them from reuptake of
serotonin and norepinephrine to increase their levels in the
synaptic cleft - Anwser//SNRIs In addition to MDD SNRIs treat -
Anwser//Anxiety and neuropathic pain (peripheral neuropathy)
Medication specific indications of duloxetine: - Anwser//urinary
incontinence and Fibromyalgia Medication specific indications
of venlafaxine: - Anwser//social anxiety, panic disorders, PTSD,
OCD, postmenopausal hot flashes Six common side effects of
SNRIs include: - Anwser//Insomnia, nausea, sexual dysfunction,
hypertension, sweating, headaches Severe side effect of SNRIs
in children/adolescents under age 25 years old: -
Anwser//suicidal ideation Life threatening adverse effect of
SNRIs, especially when used in combination with other
serotonergic drugs: - Anwser//Serotonin Syndrome This SNRI is
an inhibitor of Cytochrome P450 enzymes: -
Anwser//venlafaxine This SNRI is hepatotoxic: -
Anwser//duloxetine MAOIs increase the levels of: -
Anwser//Serotonin, Norepinephrine, and Dopamine
Norepinephrine regulates: - Anwser//alertness and focus
Dopamine regulates: - Anwser//cognitive function, motivation,
and awakeness In the synaptic cleft, Monoamine Oxidase A
breaks down: - Anwser//Serotonin, Norepinephrine, and
Dopamine In the synaptic cleft, Monoamine Oxidase B breaks
down: - Anwser//Dopamine MAOIs are especially effective in: -
Anwser//Atypical depression (mood responds to positive
events and symptoms include increased appetite, weight gain,
sleepiness, and fatigue) Non-selective MAOIs inhibit enzymes: -
Anwser//MAO-A and MAO-B Selective MAOIs only inhibit the
enzyme: - Anwser//MAO-B Three non-selective MAOIs: -
, Anwser//isocarboxazid, phenelzine, tranylcypromine Non-
selective MAOIs increase the levels of these neurotransmitters:
- Anwser//Serotonin, Norepinephrine, Dopamine These three
non-selective MAOIs bind irreversibly to MAO enzymes to
permanently block their function: - Anwser//isocarboxazid,
phenelzine, tranylcypromine Two selective MAOIs: -
Anwser//selegeline, rasagiline Selective MAOIs increase the
level of this neurotransmitter: - Anwser//Dopamine These
selective MAOIs are more commonly prescribed to treat
Parkinson's Disease (a neurodegenerative disorder that effects
the dopaminergic neurons in the substantia nigra region of the
brain): - Anwser//selegeline, rasagiline Adverse effects of
MAOIs include: - Anwser//Serotonin syndrome and
hypertensive crisis Before starting another antidepressant
MAOIs should be stopped for at least: - Anwser//Two weeks (to
allow for the body to replace MAO enzymes so that serotonin
syndrome does not occur) Five main symptoms of hypertensive
crisis: - Anwser//hyperthermia, hypertension, tachycardia,
arrhythmias, agitation Hypertensive crisis commonly occurs
when people taking MAOIs consume foods or drinks high in: -
Anwser//tyramine (cheese, wine, beer, cured/smoked meats)
Foods and drinks rich in tyramine: - Anwser//cheese, wine,
beer, cured/smoked meats When uninhibited, these two
enzymes are responsible for breaking down tyramine: -
Anwser//MAO-A and MAO-B When tyramine is not broken
down, it increases the release of this neurotransmitter, which
causes hypertensive crisis: - Anwser//Norepinephrine Due to its
action as an adrenergic antagonist this drug is the treatment of
hypertensive crisis: - Anwser//Phentolamine TCAs are
subdivided into these two groups: - Anwser//Tertiary TCAs and
Secondary TCAs Three Tertiary TCAs: - Anwser//amitriptyline,
imipramine, clomipramine Two Secondary TCAs: -
Anwser//desipramine, nortriptyline Tertiary TCAs are non-
selective and act on: - Anwser//Serotonin and Norephinephrine
transporters (increase 5HT and NE) Secondary TCAs are
ACTUAL COMPLETE FINAL EXAM 2026
QUESTIONS AND CORRECT ANSWERS
(100% CORRECT VERIFIED ANSWERS)
postsysnaptic 5HT2 receptors - Anwser//SSRIs First line therapy
for MDD due to milder side effect profiles - Anwser//SSRIs Six
Common SSRIs - Anwser//citalopram, escitalopram, fluoxetine,
fluvoxamine, sertraline, paroxetine Onset of therapeutic
benefit from SSRIs - Anwser//4-6 weeks In addition to MDD,
SSRIs also treat - Anwser//Chronic Anxiety, PTSD, OCD, and
eating disorders (bulimia) Five Common side effects of SSRIs
include - Anwser//Anxiety, insomnia, GI distress, sexual
dysfunction (ED), SIADH Severe side effect of SSRIs in
children/adolescents under age 25 years old - Anwser//suicidal
ideation Life threatening adverse effect of SSRIs, especially
when used in combination with other serotonergic drugs (SNRIs,
TCAs, MAOIs, etc.) - Anwser//Serotonin Syndrome Excess
accumulation of serotonin resulting in overstimulation of the
nervous system - Anwser//Serotonin Syndrome Seven
symptoms of Serotonin Syndrome - Anwser//Flushing,
hyperthermia, agitation, muscle rigidity, seizure, coma,
HYPERreflexia The treatment for serotonin syndrome -
Anwser//Cyproheptadine (5-HT2 receptor antagonist)
Cyproheptadine treats serotonin syndrome by -
Anwser//blocking 5-HT2 receptors (serotonin antagonist) When
SSRIs or SNRIs are stopped abruptly, common symptoms of
withdrawal include - Anwser//Irritability, headaches, and
insomnia Medicine specific side effect of citalopram -
Anwser//Prolonged QT interval (normal=0.4.-0.44 seconds) This
SSRI is pregnancy category D due to associations with
congenital heart defects - Anwser//Paroxetine All SSRIs but
,paroxetine (D) are pregnancy category - Anwser//C Three SSRIs
that are inhibitors of Cytochrome P450 enzymes -
Anwser//fluoxetine, fluvoxamine, and paroxetine Five common
SNRIs include - Anwser//duloxetine, venlafaxine,
desvenlafaxine, milnacipran, levomilnacipran This
antidepressant class of medications works by binding to
presynaptic SERT and NET to inhibit them from reuptake of
serotonin and norepinephrine to increase their levels in the
synaptic cleft - Anwser//SNRIs In addition to MDD SNRIs treat -
Anwser//Anxiety and neuropathic pain (peripheral neuropathy)
Medication specific indications of duloxetine: - Anwser//urinary
incontinence and Fibromyalgia Medication specific indications
of venlafaxine: - Anwser//social anxiety, panic disorders, PTSD,
OCD, postmenopausal hot flashes Six common side effects of
SNRIs include: - Anwser//Insomnia, nausea, sexual dysfunction,
hypertension, sweating, headaches Severe side effect of SNRIs
in children/adolescents under age 25 years old: -
Anwser//suicidal ideation Life threatening adverse effect of
SNRIs, especially when used in combination with other
serotonergic drugs: - Anwser//Serotonin Syndrome This SNRI is
an inhibitor of Cytochrome P450 enzymes: -
Anwser//venlafaxine This SNRI is hepatotoxic: -
Anwser//duloxetine MAOIs increase the levels of: -
Anwser//Serotonin, Norepinephrine, and Dopamine
Norepinephrine regulates: - Anwser//alertness and focus
Dopamine regulates: - Anwser//cognitive function, motivation,
and awakeness In the synaptic cleft, Monoamine Oxidase A
breaks down: - Anwser//Serotonin, Norepinephrine, and
Dopamine In the synaptic cleft, Monoamine Oxidase B breaks
down: - Anwser//Dopamine MAOIs are especially effective in: -
Anwser//Atypical depression (mood responds to positive
events and symptoms include increased appetite, weight gain,
sleepiness, and fatigue) Non-selective MAOIs inhibit enzymes: -
Anwser//MAO-A and MAO-B Selective MAOIs only inhibit the
enzyme: - Anwser//MAO-B Three non-selective MAOIs: -
, Anwser//isocarboxazid, phenelzine, tranylcypromine Non-
selective MAOIs increase the levels of these neurotransmitters:
- Anwser//Serotonin, Norepinephrine, Dopamine These three
non-selective MAOIs bind irreversibly to MAO enzymes to
permanently block their function: - Anwser//isocarboxazid,
phenelzine, tranylcypromine Two selective MAOIs: -
Anwser//selegeline, rasagiline Selective MAOIs increase the
level of this neurotransmitter: - Anwser//Dopamine These
selective MAOIs are more commonly prescribed to treat
Parkinson's Disease (a neurodegenerative disorder that effects
the dopaminergic neurons in the substantia nigra region of the
brain): - Anwser//selegeline, rasagiline Adverse effects of
MAOIs include: - Anwser//Serotonin syndrome and
hypertensive crisis Before starting another antidepressant
MAOIs should be stopped for at least: - Anwser//Two weeks (to
allow for the body to replace MAO enzymes so that serotonin
syndrome does not occur) Five main symptoms of hypertensive
crisis: - Anwser//hyperthermia, hypertension, tachycardia,
arrhythmias, agitation Hypertensive crisis commonly occurs
when people taking MAOIs consume foods or drinks high in: -
Anwser//tyramine (cheese, wine, beer, cured/smoked meats)
Foods and drinks rich in tyramine: - Anwser//cheese, wine,
beer, cured/smoked meats When uninhibited, these two
enzymes are responsible for breaking down tyramine: -
Anwser//MAO-A and MAO-B When tyramine is not broken
down, it increases the release of this neurotransmitter, which
causes hypertensive crisis: - Anwser//Norepinephrine Due to its
action as an adrenergic antagonist this drug is the treatment of
hypertensive crisis: - Anwser//Phentolamine TCAs are
subdivided into these two groups: - Anwser//Tertiary TCAs and
Secondary TCAs Three Tertiary TCAs: - Anwser//amitriptyline,
imipramine, clomipramine Two Secondary TCAs: -
Anwser//desipramine, nortriptyline Tertiary TCAs are non-
selective and act on: - Anwser//Serotonin and Norephinephrine
transporters (increase 5HT and NE) Secondary TCAs are
