ENDOCRINE MRCP EXAM QUESTIONS
AND ANSWERS 2026 VERIFIED.
The acidosis
usually corrects itself once the fluid and electrolyte
141
balance is restored - ANS Some physicians administer HCO3
if severe acidosis (pH < 7
a view that rapid correction of acidosis may impair
cardiac function - ANS don't administrate bicarbonate
DI If fluid
deprivation causes a urine osmolality > 300 mOsm/kg,
it suggests - ANS psychogenic (primary) polydipsia.
Postural hypotension is related to
glucocorticoid deficiency regardless of cause - ANS Addison
diagnostic test to confirm DI - ANS water deprivation test(The inability to
concentrate the urine during the test results in the plasma osmolality rising and
the urine osmolality remaining dilute. Normal plasma osmolality is 285-305
mOsm/kg. The higher the urine osmolality the more concentrated it is)
@2026/2027 ALLRIGHTS RESERVED.
,Unexplained death in childbirth
and a family history of thyroid neoplasia raise the
possibility of - ANS multiple endocrine neoplasia type-2
(phaeochromocytoma, medullary thyroid tumours and
hyperparathyroidism) as the cause of his hypertension.
Klinefelter's syndrome is a genetic disorder with an
143
extra X chromosome, giving a genotype XXY so to dx it d - ANS chromosome analysis .
Postoperative complications of thyroidectomy include - ANS recurrent laryngeal damage,
haemorrhage and
inadvertent removal of the parathyroid glands
Postoperative complications of thyroidectomy include
recurrent laryngeal damage, haemorrhage and
inadvertent removal of the parathyroid glands which can lead to
hypocalcemic symptoms The treatment of choice - ANS to
relieve the acute symptoms is 10 ml of 10% calcium
gluconate..
8.
Which of the following is the factor most likely to
make you ask her to defer pregnancy at this stage= - ANS Hb A1C 9.4%
Which of the following is most likely to need immediate referral to the ophthalmologist? -
ANS New vessels on the disc
@2026/2027 ALLRIGHTS RESERVED.
,hypoglycemic symptoms may mimics - ANS stroke symptoms esp in
elderly
preferentially take up radioactive
iodine. This makes them
particularly amenable to radioactive iodine treatment. - ANS Toxic thyroid nodules
This man has spotty skin pigmentation, probable
prolactinoma and a probable left atrial myxoma. - ANS Carney
complex is diagnosable with two features out of spotty
skin pigmentation, myxoma, endocrine tumours
(commonest being primary pigmented nodular
adrenocortical disease), but it is also associated with
Sertoli-cell tumours, growth hormone- or prolactin-producing pituitary adenomas, thyroid
adenomas and
ovarian cysts) and psammomatous melanotic
schwannoma (PMS).
MEN-2 (multiple endocrine neoplasia - type 2) is
associated with - ANS medullary thyroid carcinoma (almost
always), parathyroid chief-cell hyperplasia (10-25%)
and phaeochromocytoma (20-50%).
MEN-2b is also
146
associated with a marfanoid appearance, whereas MEN-2a is
not. The cause is - ANS an autosomal-dominant inherited
@2026/2027 ALLRIGHTS RESERVED.
, genetic mutation on the long arm of chromosome 10.
bartter syndrome as you give the patient - ANS lasix
و بيكون ف عيل صغي... كأنك مدي للعيان الزكس
A 42-year-old man is referred to the hypertension clinic for advice. He is currently
taking atenolol, bendrofluazide and ramipril and his blood pressure is currently
165/105 mmHg. His potassium is 3.0 mmol/l, with a serum bicarbonate concentration
of 28 mmol/l.
What is the best next management step - ANS Wash out as many of
147
his antihypertensive agents as is possible for a period of 2
weeks, then review
patient
with tiredness, lethargy and postural hypotension a
short period after discharge from the precipitating
illness. - ANS Waterhouse-Friderichsen syndrome
bilateral adrenal
haemorrhage occurring due to massive septicaemia, - ANS Waterhouse-Friderichsen
syndrome
Waterhouse-Friderichsen syndrome is bilateral adrenal
haemorrhage occurring due to massive septicaemia,
often associated with severe - ANS life-threatening
meningococcal disease.
@2026/2027 ALLRIGHTS RESERVED.
AND ANSWERS 2026 VERIFIED.
The acidosis
usually corrects itself once the fluid and electrolyte
141
balance is restored - ANS Some physicians administer HCO3
if severe acidosis (pH < 7
a view that rapid correction of acidosis may impair
cardiac function - ANS don't administrate bicarbonate
DI If fluid
deprivation causes a urine osmolality > 300 mOsm/kg,
it suggests - ANS psychogenic (primary) polydipsia.
Postural hypotension is related to
glucocorticoid deficiency regardless of cause - ANS Addison
diagnostic test to confirm DI - ANS water deprivation test(The inability to
concentrate the urine during the test results in the plasma osmolality rising and
the urine osmolality remaining dilute. Normal plasma osmolality is 285-305
mOsm/kg. The higher the urine osmolality the more concentrated it is)
@2026/2027 ALLRIGHTS RESERVED.
,Unexplained death in childbirth
and a family history of thyroid neoplasia raise the
possibility of - ANS multiple endocrine neoplasia type-2
(phaeochromocytoma, medullary thyroid tumours and
hyperparathyroidism) as the cause of his hypertension.
Klinefelter's syndrome is a genetic disorder with an
143
extra X chromosome, giving a genotype XXY so to dx it d - ANS chromosome analysis .
Postoperative complications of thyroidectomy include - ANS recurrent laryngeal damage,
haemorrhage and
inadvertent removal of the parathyroid glands
Postoperative complications of thyroidectomy include
recurrent laryngeal damage, haemorrhage and
inadvertent removal of the parathyroid glands which can lead to
hypocalcemic symptoms The treatment of choice - ANS to
relieve the acute symptoms is 10 ml of 10% calcium
gluconate..
8.
Which of the following is the factor most likely to
make you ask her to defer pregnancy at this stage= - ANS Hb A1C 9.4%
Which of the following is most likely to need immediate referral to the ophthalmologist? -
ANS New vessels on the disc
@2026/2027 ALLRIGHTS RESERVED.
,hypoglycemic symptoms may mimics - ANS stroke symptoms esp in
elderly
preferentially take up radioactive
iodine. This makes them
particularly amenable to radioactive iodine treatment. - ANS Toxic thyroid nodules
This man has spotty skin pigmentation, probable
prolactinoma and a probable left atrial myxoma. - ANS Carney
complex is diagnosable with two features out of spotty
skin pigmentation, myxoma, endocrine tumours
(commonest being primary pigmented nodular
adrenocortical disease), but it is also associated with
Sertoli-cell tumours, growth hormone- or prolactin-producing pituitary adenomas, thyroid
adenomas and
ovarian cysts) and psammomatous melanotic
schwannoma (PMS).
MEN-2 (multiple endocrine neoplasia - type 2) is
associated with - ANS medullary thyroid carcinoma (almost
always), parathyroid chief-cell hyperplasia (10-25%)
and phaeochromocytoma (20-50%).
MEN-2b is also
146
associated with a marfanoid appearance, whereas MEN-2a is
not. The cause is - ANS an autosomal-dominant inherited
@2026/2027 ALLRIGHTS RESERVED.
, genetic mutation on the long arm of chromosome 10.
bartter syndrome as you give the patient - ANS lasix
و بيكون ف عيل صغي... كأنك مدي للعيان الزكس
A 42-year-old man is referred to the hypertension clinic for advice. He is currently
taking atenolol, bendrofluazide and ramipril and his blood pressure is currently
165/105 mmHg. His potassium is 3.0 mmol/l, with a serum bicarbonate concentration
of 28 mmol/l.
What is the best next management step - ANS Wash out as many of
147
his antihypertensive agents as is possible for a period of 2
weeks, then review
patient
with tiredness, lethargy and postural hypotension a
short period after discharge from the precipitating
illness. - ANS Waterhouse-Friderichsen syndrome
bilateral adrenal
haemorrhage occurring due to massive septicaemia, - ANS Waterhouse-Friderichsen
syndrome
Waterhouse-Friderichsen syndrome is bilateral adrenal
haemorrhage occurring due to massive septicaemia,
often associated with severe - ANS life-threatening
meningococcal disease.
@2026/2027 ALLRIGHTS RESERVED.
