NU 545 ADVANCE PATHOPHYSIOLOGY UNIT 2
EXAM- UNIVERSITY OF SOUTH ALABAMA
QUESTIONS AND VERIFIED CORRECT ANSWERS .PDF
This quiz covers the high-yield topics from NU 545 Advance
Pathophysiology Unit 2 Exam- University of South Alabama
University it covers, including cellular adaptation, mechanisms of
injury, and inheritance. Good luck with your Advanced
Pathophysiology revision!
1
,NU 545: Advanced Pathophysiology
Expanded Practice Questions (Multiple Choice)
1. A 55-year-old male smoker presents with a persistent cough. A
biopsy of the bronchial epithelium reveals that normal columnar ciliated
cells have been replaced by stratified squamous epithelial cells. This is
an example of:
A) Dysplasia
B) Hyperplasia
C) Metaplasia
D) Anaplasia
Correct Answer: C) Metaplasia
Rationale: Metaplasia is the reversible replacement of one mature cell
type by another, often as a protective response to chronic irritation like
cigarette smoke.
2. During the vascular phase of inflammation, which mediator is
primarily responsible for the immediate "gaps" between endothelial
cells, leading to edema?
2
, A) Leukotrienes
B) Histamine
C) Cytokines
D) Prostaglandins
Correct Answer: B) Histamine
Rationale: Histamine is the principal mediator of the immediate
transient phase of increased vascular permeability.
3. Which of the following is a characteristic of Type II (Cytotoxic)
hypersensitivity?
A) It is mediated by T-lymphocytes.
B) It involves the formation of insoluble antigen-antibody complexes in
the blood.
C) Antibodies (IgG or IgM) are directed against antigens on specific cell
surfaces.
D) It is primarily caused by IgE binding to mast cells.
Correct Answer: C) Antibodies (IgG or IgM) are directed against
antigens on specific cell surfaces.
Rationale: Type II is tissue-specific, such as in blood transfusion
reactions or Goodpasture syndrome.
3
EXAM- UNIVERSITY OF SOUTH ALABAMA
QUESTIONS AND VERIFIED CORRECT ANSWERS .PDF
This quiz covers the high-yield topics from NU 545 Advance
Pathophysiology Unit 2 Exam- University of South Alabama
University it covers, including cellular adaptation, mechanisms of
injury, and inheritance. Good luck with your Advanced
Pathophysiology revision!
1
,NU 545: Advanced Pathophysiology
Expanded Practice Questions (Multiple Choice)
1. A 55-year-old male smoker presents with a persistent cough. A
biopsy of the bronchial epithelium reveals that normal columnar ciliated
cells have been replaced by stratified squamous epithelial cells. This is
an example of:
A) Dysplasia
B) Hyperplasia
C) Metaplasia
D) Anaplasia
Correct Answer: C) Metaplasia
Rationale: Metaplasia is the reversible replacement of one mature cell
type by another, often as a protective response to chronic irritation like
cigarette smoke.
2. During the vascular phase of inflammation, which mediator is
primarily responsible for the immediate "gaps" between endothelial
cells, leading to edema?
2
, A) Leukotrienes
B) Histamine
C) Cytokines
D) Prostaglandins
Correct Answer: B) Histamine
Rationale: Histamine is the principal mediator of the immediate
transient phase of increased vascular permeability.
3. Which of the following is a characteristic of Type II (Cytotoxic)
hypersensitivity?
A) It is mediated by T-lymphocytes.
B) It involves the formation of insoluble antigen-antibody complexes in
the blood.
C) Antibodies (IgG or IgM) are directed against antigens on specific cell
surfaces.
D) It is primarily caused by IgE binding to mast cells.
Correct Answer: C) Antibodies (IgG or IgM) are directed against
antigens on specific cell surfaces.
Rationale: Type II is tissue-specific, such as in blood transfusion
reactions or Goodpasture syndrome.
3
