RATED A+
Nucleoplasm - Ans substance of a cell nucleus
Chromatin Fibers - Ans DNA and protein
Nucleolus - Ans site for rRNA synthesis and processing assembly of subunits
Nuclear Pore Complex - Ans particles can pass through this
Nuclear Lamina - Ans Network of proteins that provide attachement for heterochromatin and
give the nucleus shape
Who proposed that there were functional domains of nucleus? - Ans Rabl
What can visualize and identify chromosomes? - Ans Flourescence
Functional Domains of Nucleus - Ans each chromosome occupies a distinct territory within the
nucleus and is arranged in an organized fashion. nuclei are divided into discrete funtional
domains that play an important role in regulating gene expression and in replication
How many focis of replication are in the human nucleus? - Ans greater than 100
The cell cycle consists of what? - Ans M phase and interphase (G1, S phase, G2)
, G1 Phase - Ans cell is growing and preparing for s phase
S phase - Ans when DNA synthesis occurs (replication), longest interphase cycle
G2 phase - Ans make sure you are ready to go through next round of m phase
M phase - Ans mitosis and cytokinesis (division of mother cell into two identical daughter cells)
Early replication has what gene density? - Ans high gene density, euchromatin
Late replication has what gene density? - Ans low gene density, heterochromatin
Nucleolus - Ans ribosome production facility, site for rRNA synthesis, rRNA processing,
assembly of ribosomal subunits
what are the 4 types of rRNA? - Ans 5s, 5.8s, 18s, 28s
How many copies does the human cell have of 5.8s, 18s, and 28s rRNA genes? - Ans about 280
how many copies does the human cell have of 5s rRNA genes? - Ans about 2000
Tandem arrays - Ans when 5.8s, 18s, and 28s rRNAS are transcribed by polymerase 1 into pre
rRNA
45S GENES - Ans processed into 5.8s, 18s, and 28s rRNAS are found on human chromosomes
13, 14, 15, 21, and 22