PREP STUDY GUIDE COMPREHENSIVE REVIEW
◉ Expectorants Name
(only one!). Answer: Guaifenesin
◉ Expectorants MOA. Answer: reduce thickness of secretions
disintegrates and thins secretions
◉ Expectorants Uses. Answer: common cold
bronchitis
laryngitis
pharyngitis
◉ Expectorants AE. Answer: pretty well tolerated!
minimal effects: dizziness, drowsiness, headache, nausea, abdominal
pain
◉ Antitussives types?
,(there's two!). Answer: opioid and nonopioid
◉ Antitussives Opioid Name. Answer: Codeine
Hydrocodone
◉ Antitussives Nonopioid Names. Answer: Benzonatate
Dextromethorphan
◉ Antitussives Opioid Uses. Answer: suppresses cough by acting
directly on cough center in medulla
◉ Antitussives Nonopioid uses. Answer: Supresses cough by
numbing stretch receptors; prevent refex stimulation of the
medullary cough center
◉ Antitussives Contraindications. Answer: Drug allergy
opioid dependency
respiratory depression
◉ Antitussives AE. Answer: dizziness, headache, sedation, nausea,
constipation
, ◉ Antitussives Nursing. Answer: monitor respiratory and cough
assessment
instruct pts to avoid driving or operating heavy equipment because
of possible sedation
report: coughs lasting more than 1 week, persistent headache
ANTITUSSIVES ARE FOR NONPRODUCTIVE COUGHS; THEY DON'T
SUPPRESS A PRODUCTIVE COUGH
◉ Mucolytic Agents Name
(only one!). Answer: Acetylcysteine
◉ Mucolytic Agents MOA. Answer: works directly on mucus to
reduce thickness
alters metabolism of acetaminophen to decrease injury to the liver
in overdose
◉ Mucolytic Agents Pharmacodynamics. Answer: splits disulfide link
in mucoproteins; reduces thickness, facilitates removal of secretions
◉ Mucolytic Agents AE. Answer: resp distress
bronchospasm