N5315 Advanced Pathophysiology –
Cancer Actual Questions 2026 With
Verified Answers
Oncogene (function) - correct-answer -Function independent of normal regulator
cellular mechanisms allowing cancer cell proliferarion.
Autocrine Stimulation - correct-answer -Oncogenes provide cancer cells with the
ability to secrete growth factors which stimulate their own growth.
(HER2) Human Epithelial growth factor Receptor 2 - correct-answer -Responsive to
low levels of epidermal growth factor & this stimulates the breast cancer growth.
HER2 Receptor Inhibitors - correct-answer -A receptor that is a target of some
drugs used to treat breast cancer.
Activates Oncogenes - correct-answer -Genetic events such as:
, 2
Point Mutations
Translocations
Gene Amplification
Inactivation of tumor suppressor genes are responsible for: - correct-answer -
Contributing to the unregulated growth and controlling the cellular proliferation
of cancer cells.
Anti-oncogenes - correct-answer -Tumor suppressor genes
Inactivated tumor suppressor genes stop what? - correct-answer -They stop cell
division in damaged cells and prevent mutations.
Two Suppressor Genes - correct-answer -Located in each cell and both must be
inactivated (turned off) by cancer.
The p53 tumor suppressor gene produces what? - correct-answer -The p53
protein that is responsible for monitoring cellular stress and for activating the
caretaker gene.