Briefly describe the functions of the digestive system - Answers Ingestion - Consumption through the
mouth in solid or liquid form
Digestion -
Breakdown of large organic molecules into smaller absorbable molecules
Absorption -
Movement of molecules out of the digestive tract and into the blood or lymphatic system
Elimination -
Removal of undigested material through feces
Describe the structure and general functional roles of the four tunics (layers) of the digestive tract and
briefly highlight the differences between the different organs related to their specialized functions -
Answers The four tunics include:
- Muscosa
Consists of the muscosa epithelium, lamina propria, muscularis mucosae
- Submucosa
Thick layer of connective tissue that contains nerves, vessels and glands
- Muscularis
Inner layer of smooth muscle and outer layer of longitudinal smooth muscle
- Serosa (Adventitia)
Smooth epethelial layer with connective tissue
Name and describe the three phases of deglutition (swallowing). Include the relevant anatomy
involved in each phase - Answers Divided into:
- Voluntary phase
Bolus or mass is formed in the mouth with the tongue pushing it towards the hard palate and into the
oropharynx
- Pharyngeal phase
Soft palate elevates to block the nasopharynx keeping the larynx and pharynx elevated. Epiglottis is
pushed down over the larynx. Bolus is pushed into the esophagus.
- Esophageal phase
Peristaltic contractions move the bolus down the esophagus towards the stomach
Describe the cephalic phase of stomach secretion. Include the function, stimulation for release and
gland of origin of each secretion. - Answers Smells of food and relevant thoughts trigger the medulla
oblongata to influence gastric secretions.
The enteric plexus becomes stimulated by preganglionic neurons which stimulates secretory cells in
the stomach to release:
Hydrochloric acid
Mucus
Intrinsic factor
Gastrin
Histamine
All released by parietal and chief cells
, Describe the intestinal phase of stomach secretion. Describe the hormones and pathways involved in
modifying gastric activity - Answers Inhibits gastric secretions and is controlled by the entrance of
acidic chyme into the duodenum
When pH of chyme drops below 2.0 the inhibitory effect of the intestinal phase is greatest
With low pH the hormone secretin is released to stop gastric secretions. Fatty acids and peptides
release cholecystokinin also inhibiting gastric secretions.
Negative feedback loop that raises pH
Compare and contrast the structure of the mucosal layers of the stomach and small intestine. What
does this tell you about the roles of the stomach and small intestine within the digestive system?
Provide a brief description of two specialized structures from each organ's mucosal layer to support
your discussion of its role. - Answers Surface mucosal cells of the stomach:
Inner surface of the stomach and lining of the gastric pits
Produce mucous
Chief cells of the stomach:
secrete pepsinogen which is a precursor for pepsin
Mucosa cells of the small intestine: Absorptive cells that produce digestive enzymes and absorb
digested food.
Epithelial cells of the Small intestine: Secretes peptidases and disaccharidases
The Small intestine and stomach play a key role in digesting foods to their most basic components and
preparing them for more extensive absorption
Describe the control of release and function of each of the secretions from the exocrine pancreas. -
Answers Bicarbonate Ions:
- Neutralize chyme from the stomach and allows pancreatic enzymes to function
- Released by the presence of chyme in the duodenum
Proteolytic Enzymes:
- Includes trypsin, chymotrypsin and carboxypeptidase and all continue protein digestion started in
the stomach
- Release triggered by cholecystokinin
Pancreatic Amylase:
- Continues polysaccharide digestion
- Release triggered by cholecystokinin
Lipase:
- Digests lipids
- Release triggered by cholecystokinin
Nuclease:
- Degrades DNA and RNA to
nucleotides
- Release triggered by cholecystokinin
Parasympathetic stimulation causes further stimulation through the vagus nerve leading to more
pancreatic enzyme release
Distinguish between the processes of digestion and absorption through definition and description.
Where in the gastrointestinal system do they generally take place? - Answers Absorption: