WGU BIOCHEMISTRY 785 CERTIFICATION
SCRIPT 2026 COMPLETE QUESTIONS AND
CORRECT ANSWERS
◉Low levels of glutathione are associated with neurological,
immunological, and cardiovascular impairments. Two enzymatic
reactions are involved in the synthesis of glutathione. In the second
enzymatic reaction, glutathione synthetase converts glycine to
glutathione. What would potentially decrease risks associated with
low levels of glutathione?
Increasing the amount of glycine in the diet
Noncompetitive inhibitor of glutathione synthetase
Uncompetitive inhibitor of glutathione synthetase
Decreasing the amount of glycine in the diet. Answer: Increasing the
amount of glycine in the diet
,One way to increase glutathione levels is to increase the activity of
glutathione synthetase. Glutathione synthetase activity can be
increased by increasing the amount of substrate, or glycine available.
◉Which class of enzymes impacts protein function by temporarily
removing a phosphate?
Kinase
Phosphatase
Polypeptide
Lactase. Answer: Phosphatase
Phosphatases are enzymes that remove phosphate groups from the
substrates.
◉How does the activation energy of enzyme-catalyzed reactions
compare to those of corresponding uncatalyzed reactions?
The activation energy of enzyme-catalyzed reactions are the same as
uncatalyzed reactions
,The activation energy of the enzyme-catalyzed reactions only
changes in response to temperature.
The activation energy of enzyme-catalyzed reactions are lower than
the uncatalyzed reaction
The activation energy of enzyme-catalyzed reactions are higher than
uncatalyzed reactions. Answer: The activation energy of enzyme-
catalyzed reactions are lower than the uncatalyzed reaction
The activation energy is the amount of energy needed to get the
reaction started and over the energy hill to form products. Enzymes
reduce the amount of energy needed to start the reaction or lower
the amount of energy needed to climb the energy hill.
◉A final product of a four-step metabolic pathway serves as a
noncompetitive inhibitor, binding to an enzyme in this pathway and
temporarily turning off the pathway. Which enzyme is most likely to
be targeted by the inhibitor?
The final enzyme in the pathway
The first enzyme in the pathway
, Any enzyme in the middle of the pathway
The second enzyme in the pathway. Answer: The first enzyme in the
pathway
The final product's structure is more unlike the substrate for the
first enzyme in the pathway than any other, and thus the least likely
to fit the active site of enzyme 1.
◉Which of the following could be a potential ramification of a
defective nucleotide excision repair (NER) pathway?
Thymine dimers would be fixed by DNA polymerase, increasing the
probability of developing skin cancer.
Thymine dimers would accumulate and increase the probability of
developing skin cancer.
Thymine dimers, caused by UV light, would be repaired, decreasing
the probability of developing skin cancer.
SCRIPT 2026 COMPLETE QUESTIONS AND
CORRECT ANSWERS
◉Low levels of glutathione are associated with neurological,
immunological, and cardiovascular impairments. Two enzymatic
reactions are involved in the synthesis of glutathione. In the second
enzymatic reaction, glutathione synthetase converts glycine to
glutathione. What would potentially decrease risks associated with
low levels of glutathione?
Increasing the amount of glycine in the diet
Noncompetitive inhibitor of glutathione synthetase
Uncompetitive inhibitor of glutathione synthetase
Decreasing the amount of glycine in the diet. Answer: Increasing the
amount of glycine in the diet
,One way to increase glutathione levels is to increase the activity of
glutathione synthetase. Glutathione synthetase activity can be
increased by increasing the amount of substrate, or glycine available.
◉Which class of enzymes impacts protein function by temporarily
removing a phosphate?
Kinase
Phosphatase
Polypeptide
Lactase. Answer: Phosphatase
Phosphatases are enzymes that remove phosphate groups from the
substrates.
◉How does the activation energy of enzyme-catalyzed reactions
compare to those of corresponding uncatalyzed reactions?
The activation energy of enzyme-catalyzed reactions are the same as
uncatalyzed reactions
,The activation energy of the enzyme-catalyzed reactions only
changes in response to temperature.
The activation energy of enzyme-catalyzed reactions are lower than
the uncatalyzed reaction
The activation energy of enzyme-catalyzed reactions are higher than
uncatalyzed reactions. Answer: The activation energy of enzyme-
catalyzed reactions are lower than the uncatalyzed reaction
The activation energy is the amount of energy needed to get the
reaction started and over the energy hill to form products. Enzymes
reduce the amount of energy needed to start the reaction or lower
the amount of energy needed to climb the energy hill.
◉A final product of a four-step metabolic pathway serves as a
noncompetitive inhibitor, binding to an enzyme in this pathway and
temporarily turning off the pathway. Which enzyme is most likely to
be targeted by the inhibitor?
The final enzyme in the pathway
The first enzyme in the pathway
, Any enzyme in the middle of the pathway
The second enzyme in the pathway. Answer: The first enzyme in the
pathway
The final product's structure is more unlike the substrate for the
first enzyme in the pathway than any other, and thus the least likely
to fit the active site of enzyme 1.
◉Which of the following could be a potential ramification of a
defective nucleotide excision repair (NER) pathway?
Thymine dimers would be fixed by DNA polymerase, increasing the
probability of developing skin cancer.
Thymine dimers would accumulate and increase the probability of
developing skin cancer.
Thymine dimers, caused by UV light, would be repaired, decreasing
the probability of developing skin cancer.
