Chapter 28 COPD and
Asthma Management Study
Guide and Practice
Questions
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Terms in this set (86)
Which physiologic effect of ongoing tobacco smoking leads to chronic
obstructive pulmonary disease (COPD)?
1
Respiratory tract cell hyperplasia
2
Impairment of the cough reflex
3
Increased antiprotease levels
4
Reversible airway inflammation
1
Hyperplasia of cells lining the respiratory tract leads to increased mucus
production and narrowing of airways and eventually to symptoms of COPD.
Frequent coughing is a symptom of COPD, but the cough reflex is not affected
by smoking. Tobacco use leads to lower levels of antiproteases, which results
in unimpeded destruction of elastin and collagen fibers by proteases. Tobacco
smoking causes irreversible airway thickening; reversible airway inflammation
is associated with asthma.
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