ONS Chemotherapy Immunotherapy Certification 2026 |
100+ Most Tested Questions | Verified Q&A
1. Name a well-known tumor suppressor gene that plays a critical role in cancer
prevention.
BRCA1
HER2
Ras
p53
2. Plant alkaloids main drug
Cyclophosphamide (Cytoxan)
Fluorouracil
Doxorubicin (Adriamycin)
Vincristine (Oncovin)
3. Antitumor antibiotics (anthracyclines) include:
Mitoxantrone
All the above
Daunorubicin
Idarubicin
Doxorubicin
Epirubicin
4. The p53 gene is often mutated in human cancers. It is referred to as a(n):
, oncogene
phosphogene
neurogene
tumor suppressor gene
5. Describe how antimetabolites exert their effects on cancer cells and the
resulting side effects.
Antimetabolites interfere with DNA synthesis, leading to side
effects such as nausea and bone marrow suppression.
Antimetabolites block protein synthesis, leading to liver damage and
skin rash.
Antimetabolites promote cell division, resulting in hair loss and weight
gain.
Antimetabolites enhance immune response, causing fatigue and fever.
6. If a patient undergoing treatment with antimetabolites experiences severe
nausea and low blood cell counts, what might this indicate about the
effectiveness and side effects of their treatment?
The patient is developing resistance to the antimetabolites.
The treatment is ineffective and should be stopped immediately.
The patient is experiencing an allergic reaction to the medication.
The treatment is likely effective but causing significant side effects.
7. Lifetime cumulative dose of 400 units and WHY?
Vincristine
Bleomycin
, Doxorubicin
Cisplatin
8. Which is an example of an oncogene?
Retinoblastoma
BRCA
BCR/ABL
9. Which of the following drugs is most nephrotoxic?
Carboplatin
Methotrexate
Vincristine
Cisplatin
10. Which type of immune cells are primarily responsible for cell-mediated
immunity?
Macrophages
T cells
B cells
Natural killer cells
11. Discuss the implications of nephrotoxicity in chemotherapy and how it affects
treatment decisions.
Nephrotoxicity only affects the efficacy of chemotherapy drugs.
Nephrotoxicity is irrelevant to treatment decisions.
, Nephrotoxicity can lead to kidney damage, necessitating careful
monitoring and potential dose adjustments in chemotherapy.
Nephrotoxicity is a minor side effect that does not require attention.
12. If a patient with a history of lung disease is scheduled to receive bleomycin,
what precautionary measures should be taken to minimize the risk of
anaphylaxis?
Administering the drug at a faster rate.
Avoiding any pre-treatment assessments.
Pre-medication with antihistamines and close monitoring during
administration.
Using a higher dose of bleomycin.
13. Describe the function of proto-oncogenes and how they differ from tumor
suppressor genes.
Proto-oncogenes promote cell growth, while tumor suppressor
genes inhibit cell division.
Proto-oncogenes repair DNA, while tumor suppressor genes
promote cell growth.
Proto-oncogenes have no role in cell division, while tumor
suppressor genes promote it.
Proto-oncogenes induce apoptosis, while tumor suppressor genes
prevent it.
14. What does ANC stand for in the context of chemotherapy?
Absolute Neutrophil Concentration
Adjusted Neutrophil Count
100+ Most Tested Questions | Verified Q&A
1. Name a well-known tumor suppressor gene that plays a critical role in cancer
prevention.
BRCA1
HER2
Ras
p53
2. Plant alkaloids main drug
Cyclophosphamide (Cytoxan)
Fluorouracil
Doxorubicin (Adriamycin)
Vincristine (Oncovin)
3. Antitumor antibiotics (anthracyclines) include:
Mitoxantrone
All the above
Daunorubicin
Idarubicin
Doxorubicin
Epirubicin
4. The p53 gene is often mutated in human cancers. It is referred to as a(n):
, oncogene
phosphogene
neurogene
tumor suppressor gene
5. Describe how antimetabolites exert their effects on cancer cells and the
resulting side effects.
Antimetabolites interfere with DNA synthesis, leading to side
effects such as nausea and bone marrow suppression.
Antimetabolites block protein synthesis, leading to liver damage and
skin rash.
Antimetabolites promote cell division, resulting in hair loss and weight
gain.
Antimetabolites enhance immune response, causing fatigue and fever.
6. If a patient undergoing treatment with antimetabolites experiences severe
nausea and low blood cell counts, what might this indicate about the
effectiveness and side effects of their treatment?
The patient is developing resistance to the antimetabolites.
The treatment is ineffective and should be stopped immediately.
The patient is experiencing an allergic reaction to the medication.
The treatment is likely effective but causing significant side effects.
7. Lifetime cumulative dose of 400 units and WHY?
Vincristine
Bleomycin
, Doxorubicin
Cisplatin
8. Which is an example of an oncogene?
Retinoblastoma
BRCA
BCR/ABL
9. Which of the following drugs is most nephrotoxic?
Carboplatin
Methotrexate
Vincristine
Cisplatin
10. Which type of immune cells are primarily responsible for cell-mediated
immunity?
Macrophages
T cells
B cells
Natural killer cells
11. Discuss the implications of nephrotoxicity in chemotherapy and how it affects
treatment decisions.
Nephrotoxicity only affects the efficacy of chemotherapy drugs.
Nephrotoxicity is irrelevant to treatment decisions.
, Nephrotoxicity can lead to kidney damage, necessitating careful
monitoring and potential dose adjustments in chemotherapy.
Nephrotoxicity is a minor side effect that does not require attention.
12. If a patient with a history of lung disease is scheduled to receive bleomycin,
what precautionary measures should be taken to minimize the risk of
anaphylaxis?
Administering the drug at a faster rate.
Avoiding any pre-treatment assessments.
Pre-medication with antihistamines and close monitoring during
administration.
Using a higher dose of bleomycin.
13. Describe the function of proto-oncogenes and how they differ from tumor
suppressor genes.
Proto-oncogenes promote cell growth, while tumor suppressor
genes inhibit cell division.
Proto-oncogenes repair DNA, while tumor suppressor genes
promote cell growth.
Proto-oncogenes have no role in cell division, while tumor
suppressor genes promote it.
Proto-oncogenes induce apoptosis, while tumor suppressor genes
prevent it.
14. What does ANC stand for in the context of chemotherapy?
Absolute Neutrophil Concentration
Adjusted Neutrophil Count
