MODULE 4 - PCOL & PHARMACOKINETICS
QUESTIONS WITH COMPLETE SOLUTIONS
[A patient is treated at the Emergency Room for an infection.
She has an allergy to Penicillin that was documented in her
medical chart.]
If an antimicrobial is being considered for this patient, which of
the following may cause cross-sensitivity?
a. Doxycycline
b. Amikacin
c. Clindamycin
d. Imipenem Correct Answers D
[A patient was brought to the Emergency Room due to an
attempted suicide through exposure to a large amount of a kind
of insecticide. Based on the literature, the toxicity of the patients
is due to its anticholinesterase effect.]
Which of the following antidotes needs to be administered to the
patient?
a. Cyproheptadine
b. Atropine
c. Physostigmine
d. Flumazenil Correct Answers B
[A patient was brought to the Emergency Room due to an
attempted suicide through exposure to a large amount of a kind
,of insecticide. Based on the literature, the toxicity of the patients
is due to its anticholinesterase effect.]
Which of the following insecticides would have been the
causative agent?
a. Organochloride
b. Pyrethroid
c. Organophosphate
d. Rotenoid Correct Answers C
[A patient was brought to the Emergency Room due to an
attempted suicide through exposure to a large amount of a kind
of insecticide. Based on the literature, the toxicity of the patients
is due to its anticholinesterase effect.]
Which of the following toxidromes would be consistent to the
effect of the insecticide?
I. Increased sweating
II. Bronchodilation
III. Drooling
a. I & III
b. II & IIII
c. I & II
d. I, II & III Correct Answers A
[A poison control and management team in the hospital was
formed. Among their numerous functions was to prepare a
standard Poison Kit containing various antidotes.]
,Which of the of the following poisons would be indicated for
treatment by Physostigmine?
a. Muscarinic Antagonists
b. Muscarinic Agonists
c. Benzodiazepines
d. Carbamates Correct Answers A
[see figure in test paper, #87]
Based on the figure below, which of the following new drugs
would be the most potent?
a. B
b. C
c. D
d. A Correct Answers D
[see figure in test paper, #96-98]
How many hours did a Trough Level reach the therapeutic
range?
a. 32 hours
b. 40 hours
c. 24 hours
d. 16 hours Correct Answers D
[see figure in test paper, #96-98]
, Identify the parameters A and B in the figure used in
determining the therapeutic range.
a. A - Minimum Effective Concentration; B - Maximum Toxic
Concentration
b. A - Minimum Effective Concentration; B - Minimum Toxic
Concentration
c. A - Minimum Toxic Concentration; B - Minimum Effective
Concentration
d. A - Maximum Toxic Concentration; B - Maximum Effective
Concentration Correct Answers B
[see figure in test paper, #96-98]
What would most likely be the reason for the drug's increasing
plasma concentration towards reaching the therapeutic range?
a. Decreasing clearance of the drug over thru time.
b. Faster absorption of the drug thru time.
c. Faster distribution of the drug to the receptor sites. d. Giving
of maintenance doses. Correct Answers D
5-HT3 antagonists are used as an ________.
a. Antidiabetic
b. Anticancer
c. Antiemetic
d. Antiasthma Correct Answers C
QUESTIONS WITH COMPLETE SOLUTIONS
[A patient is treated at the Emergency Room for an infection.
She has an allergy to Penicillin that was documented in her
medical chart.]
If an antimicrobial is being considered for this patient, which of
the following may cause cross-sensitivity?
a. Doxycycline
b. Amikacin
c. Clindamycin
d. Imipenem Correct Answers D
[A patient was brought to the Emergency Room due to an
attempted suicide through exposure to a large amount of a kind
of insecticide. Based on the literature, the toxicity of the patients
is due to its anticholinesterase effect.]
Which of the following antidotes needs to be administered to the
patient?
a. Cyproheptadine
b. Atropine
c. Physostigmine
d. Flumazenil Correct Answers B
[A patient was brought to the Emergency Room due to an
attempted suicide through exposure to a large amount of a kind
,of insecticide. Based on the literature, the toxicity of the patients
is due to its anticholinesterase effect.]
Which of the following insecticides would have been the
causative agent?
a. Organochloride
b. Pyrethroid
c. Organophosphate
d. Rotenoid Correct Answers C
[A patient was brought to the Emergency Room due to an
attempted suicide through exposure to a large amount of a kind
of insecticide. Based on the literature, the toxicity of the patients
is due to its anticholinesterase effect.]
Which of the following toxidromes would be consistent to the
effect of the insecticide?
I. Increased sweating
II. Bronchodilation
III. Drooling
a. I & III
b. II & IIII
c. I & II
d. I, II & III Correct Answers A
[A poison control and management team in the hospital was
formed. Among their numerous functions was to prepare a
standard Poison Kit containing various antidotes.]
,Which of the of the following poisons would be indicated for
treatment by Physostigmine?
a. Muscarinic Antagonists
b. Muscarinic Agonists
c. Benzodiazepines
d. Carbamates Correct Answers A
[see figure in test paper, #87]
Based on the figure below, which of the following new drugs
would be the most potent?
a. B
b. C
c. D
d. A Correct Answers D
[see figure in test paper, #96-98]
How many hours did a Trough Level reach the therapeutic
range?
a. 32 hours
b. 40 hours
c. 24 hours
d. 16 hours Correct Answers D
[see figure in test paper, #96-98]
, Identify the parameters A and B in the figure used in
determining the therapeutic range.
a. A - Minimum Effective Concentration; B - Maximum Toxic
Concentration
b. A - Minimum Effective Concentration; B - Minimum Toxic
Concentration
c. A - Minimum Toxic Concentration; B - Minimum Effective
Concentration
d. A - Maximum Toxic Concentration; B - Maximum Effective
Concentration Correct Answers B
[see figure in test paper, #96-98]
What would most likely be the reason for the drug's increasing
plasma concentration towards reaching the therapeutic range?
a. Decreasing clearance of the drug over thru time.
b. Faster absorption of the drug thru time.
c. Faster distribution of the drug to the receptor sites. d. Giving
of maintenance doses. Correct Answers D
5-HT3 antagonists are used as an ________.
a. Antidiabetic
b. Anticancer
c. Antiemetic
d. Antiasthma Correct Answers C
