Galen Pharmacology Test 1 questions with accurate detailed
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solutions
ear drops - ✔✔INSTILL AT ROOM TEMP/ child- down and back/ adult- up and back
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eye drops - ✔✔important to instill the eye drop medication into the conjunctival sac (not
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the eyeball/cornea). inner to outer
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enema - ✔✔patient lays on left side
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pharmacokinetic - ✔✔what happens in the body once med is administered || || || || || || || || || ||
-Absorption
-Distribution/ Binding ||
-Metabolism
-Renal Excretion ||
first-pass effect - ✔✔A swallowed pill that goes into the liver through the portal vein where
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some of the drug becomes inactive
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protein binding - ✔✔protein (usually albumin) binds to medication to help chemicals move
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through.
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When the medication is bound to the protein it is not available to perform its action in the
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body ||
True or False - ✔✔True
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,2
free drug - ✔✔The amount that is left not bound called the__________________and it
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performs the pharmacologic response || || ||
pharmacodynamics phase - ✔✔refers to the effects drugs will have on a patient and the || || || || || || || || || || || || || || ||
mechanism of their actions. || || ||
How do antacids affect drug absorption? - ✔✔Antacids increase the PH (alkaline) of gastric
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juices which causes a decrease in the disintegration process
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Most drugs (excluding enteric coated or XR) need an acidic environment to break down.
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Lipid soluble drugs are not able to pass the membrane without a protein/ enzyme carrier.
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True or false - ✔✔False
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In the GI tract the lining is made up of a mucous membrane composed of lipids and
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proteins which allows lipid soluble drugs to easily pass through. If the drug is water soluble
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it will need a protein or enzyme carrier to pass through
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Benzodiazepine - ✔✔Alprazolam, Midazolam, Lorazepam,Diazepam || || || ||
NMS or Neuroleptic Malignant Syndrome - ✔✔Delirium with fever, catalepsy, and muscle
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rigidity, and blood || ||
pressure instability ||
What 2 types of medication can cause Neuroleptic Malignant Syndrome? -
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✔✔antipsychotics and antiemetics can cause this life threatening condition || || || || || || || ||
Local anesthetic - ✔✔Lidocaine
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, 2
NSAID - ✔✔Ibuprofen
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NSAID Cox-2 Inhibitor - ✔✔Celecoxib
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non-opiod analgesic - ✔✔acetaminophen || || ||
non benzodiazepine - ✔✔zolpidem
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Spinal anethesia - ✔✔Spinal/Epidural
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Nsaid-Salicylate - ✔✔Aspirin || ||
Anti-gout - ✔✔allopurinol || ||
opioid - ✔✔morphine sulphate
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opioid antagonist - ✔✔naloxone
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CNS Stimulant-amphetemine-like - ✔✔Methylphenidate
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Hydantoin, Antiepileptics - ✔✔Phenytoin || || ||
Valproate - ✔✔valporic acid || || ||
Barbituate - ✔✔Phenobarbital || ||