2
MSN 611 - Pharm Final Exam Information questions with
|| || || || || || || || ||
accurate answers ||
Nursing Fundamentals ||
IV route is the fastest
|| || || ||
Pharmacokinetics
ADME
1. Absorption: how medication gains access to the body
|| || || || || || || ||
2. Distribution
||
3. Metabolism
||
4. Excretion
||
1st pass effect
|| ||
When a drug is metabolized at a specific point in the body, resulting in a lower
|| || || || || || || || || || || || || || || ||
concentration of the active substance. || || || || ||
This phenomenon is termed the first-pass effect and is most often described in the context
|| || || || || || || || || || || || || || ||
of absorption of chemicals following ingestion. In general, the first-pass effect after oral
|| || || || || || || || || || || || ||
absorption is the result of efficient uptake and metabolism of compounds by the liver.
|| || || || || || || || || || || || ||
,2
Generic vs Brand || ||
A medication only has ONE generic name but can have MULTIPLE brand names (ex:
|| || || || || || || || || || || || || ||
ibuprofen; MOTRIN/ADVIL) ||
When should a patient be assessed before administering a medication?
|| || || || || || || || ||
The patient should be assessed right before administration of a drug (ex: assess BP prior to
|| || || || || || || || || || || || || || || ||
administering a BP med) || || ||
What assessment in a patient needs immediate intervention?
|| || || || || || ||
Oliguria or anuria || ||
NSAIDS
Nephrotoxic & Hepatotoxic || || ||
COX-1/COX-2 inhibitors with the exception of Celecoxib || || || || || || ||
#1 Adverse Effect: GI bleeding (fecal occult blood test)
|| || || || || || || ||
Acetaminophen
Hepatotoxic
, 2
Not an antiinflammatory
|| ||
Corticosteroids
Different routes--> inhaled, intranasal, IM, topical
|| || || || ||
Major systemic adverse effects: hyperglycemia, HTN, depressed immune function,
|| || || || || || || || ||
decreased bone density (for these reasons we do NOT like to administer steroids
|| || || || || || || || || || || || ||
systemically)
What reasons are steroids used?
|| || || ||
Asthma, cancer, nausea, etc.|| || ||
Serotonin 5-HT Receptor Agonists (-triptans)
|| || || ||
Work to treat migraines
|| || ||
Migraines are most common in females || || || || ||
These medications are TERATOGENIC
|| || ||
Contraindicated in patients with cardiac disease, HTN, or taking other medications such as
|| || || || || || || || || || || || ||
SSRIs/SNRIs
MSN 611 - Pharm Final Exam Information questions with
|| || || || || || || || ||
accurate answers ||
Nursing Fundamentals ||
IV route is the fastest
|| || || ||
Pharmacokinetics
ADME
1. Absorption: how medication gains access to the body
|| || || || || || || ||
2. Distribution
||
3. Metabolism
||
4. Excretion
||
1st pass effect
|| ||
When a drug is metabolized at a specific point in the body, resulting in a lower
|| || || || || || || || || || || || || || || ||
concentration of the active substance. || || || || ||
This phenomenon is termed the first-pass effect and is most often described in the context
|| || || || || || || || || || || || || || ||
of absorption of chemicals following ingestion. In general, the first-pass effect after oral
|| || || || || || || || || || || || ||
absorption is the result of efficient uptake and metabolism of compounds by the liver.
|| || || || || || || || || || || || ||
,2
Generic vs Brand || ||
A medication only has ONE generic name but can have MULTIPLE brand names (ex:
|| || || || || || || || || || || || || ||
ibuprofen; MOTRIN/ADVIL) ||
When should a patient be assessed before administering a medication?
|| || || || || || || || ||
The patient should be assessed right before administration of a drug (ex: assess BP prior to
|| || || || || || || || || || || || || || || ||
administering a BP med) || || ||
What assessment in a patient needs immediate intervention?
|| || || || || || ||
Oliguria or anuria || ||
NSAIDS
Nephrotoxic & Hepatotoxic || || ||
COX-1/COX-2 inhibitors with the exception of Celecoxib || || || || || || ||
#1 Adverse Effect: GI bleeding (fecal occult blood test)
|| || || || || || || ||
Acetaminophen
Hepatotoxic
, 2
Not an antiinflammatory
|| ||
Corticosteroids
Different routes--> inhaled, intranasal, IM, topical
|| || || || ||
Major systemic adverse effects: hyperglycemia, HTN, depressed immune function,
|| || || || || || || || ||
decreased bone density (for these reasons we do NOT like to administer steroids
|| || || || || || || || || || || || ||
systemically)
What reasons are steroids used?
|| || || ||
Asthma, cancer, nausea, etc.|| || ||
Serotonin 5-HT Receptor Agonists (-triptans)
|| || || ||
Work to treat migraines
|| || ||
Migraines are most common in females || || || || ||
These medications are TERATOGENIC
|| || ||
Contraindicated in patients with cardiac disease, HTN, or taking other medications such as
|| || || || || || || || || || || || ||
SSRIs/SNRIs
