2
MSN 611 Midterm Exam Questions with precise answers
|| || || || || || ||
Eosinophils, neutrophils, and T cells contain the type of histamine receptors referred to as:
|| || || || || || || || || || || || ||
a. H1
||
b. H2
||
c. H3
||
d. H4 - ✔✔d. H4
|| || || ||
Some 1st generation antihistamines are used to treat
|| || || || || || ||
a. as stimulants
|| ||
b. to prevent motion sickness
|| || || ||
c. as anticonvulsants
|| ||
d. as laxatives - ✔✔b. to prevent motion sickness
|| || || || || || || ||
2nd generation antihistamines are preferred for treating which patient category?
|| || || || || || || || ||
a. children
||
b. women
||
c. patients with hypertension
|| || || ||
d. patients with insomnia - ✔✔a. children
|| || || || || ||
Compared to 1st generation antihistamines, 2nd generation antihistamines:
|| || || || || || ||
,2
a. are less able to penetrate the blood brain barrier
|| || || || || || || || ||
b. have fewer muscarinic effects
|| || || ||
c. have greater anticholinergic effects
|| || || ||
d. are more likely to cause drowsiness - ✔✔a. are less able to penetrate the blood brain
|| || || || || || || || || || || || || || || || ||
barrier
Which types of antihistamines are used to inhibit the secretion of gastric acid in patients
|| || || || || || || || || || || || || || ||
with gastrointestinal disorders?
|| ||
a. H1
||
b. H2
||
c. H3
||
d. H4 - ✔✔b. H2
|| || || ||
Under what two circumstances may 2nd generation antihistamines cause drowsiness?
|| || || || || || || || ||
a. if used concurrently with medications that cause CNS depression or with alcohol
|| || || || || || || || || || || ||
b. if used concurrently with medications that cause CNS depression
|| || || || || || || || ||
c. if they are taken with OTC medications
|| || || || || || ||
d. if they are taken with alcohol - ✔✔a. if used concurrently with medications that cause
|| || || || || || || || || || || || || || || ||
CNS depression or with alcohol
|| || || ||
Why is it important for antiviral compounds to be able to discriminate between host and
|| || || || || || || || || || || || || || ||
viral functions with a high degree of specificity?
|| || || || || || ||
a. available antiviral agents mainly target stages in the viral life cycle
|| || || || || || || || || || ||
,2
b. to avoid attacking host cells, since viruses replicate intracellularly and often use host cell
|| || || || || || || || || || || || || || ||
enzymes, macromolecules, and organelles to make their own particles
|| || || || || || || || ||
c. in recent years the demand for new antiviral strategies has increased marketably - ✔✔b.
|| || || || || || || || || || || || || || ||
to avoid attacking host cells, since viruses replicate intracellularly and often use host cell
|| || || || || || || || || || || || || ||
enzymes, macromolecules, and organelles to make their own particles
|| || || || || || || ||
Which of the following statements pertains to antimicrobial therapy?
|| || || || || || || ||
a. lower dosage levels of antimicrobial therapy can help prevent allergic responses
|| || || || || || || || || || ||
b. a differential diagnosis should indicate whether an infection is self-limiting
|| || || || || || || || || || ||
c. self-limiting infections often require antimicrobial therapy
|| || || || || ||
d. in cases of sepsis, laboratory specimens are not required - ✔✔b. a differential diagnosis
|| || || || || || || || || || || || || || ||
should indicate whether an infection is self-limiting
|| || || || || ||
Chose the correct statement describing antibacterial drugs:
|| || || || || ||
a. antibiotics are developed to have similar required exposure times across drug classes
|| || || || || || || || || || || ||
b. Penicillinase-resistant penicillins are the agents of choice for most staphylococcal disease
|| || || || || || || || || || ||
c. narrow therapeutic agents have a higher safety tolerance for large fluctuations of drug in
|| || || || || || || || || || || || || || ||
the blood
||
d. therapeutic levels of antibacterial agents are established during tissue culture studies -
|| || || || || || || || || || || || ||
✔✔b. Penicillinase-resistant penicillins are the agents of choice for most staphylococcal
|| || || || || || || || || || ||
disease
The available modes of action of antihelmintic drugs is/are:
|| || || || || || || ||
a. excrete in the intestine
|| || || ||
, 2
b. locally within the gut lumen to cause expulsion of worms from the GI tract and
|| || || || || || || || || || || || || || || ||
systemically against helminths residing outside the GI tract || || || || || || ||
c. is likely present in virtually every mammal residing in a "natural" habitat
|| || || || || || || || || || || ||
d. systemically against helminths residing outside the GI tract - ✔✔b. locally within the gut
|| || || || || || || || || || || || || || ||
lumen to cause expulsion of worms from the GI tract and systemically against helminths
|| || || || || || || || || || || || || ||
residing outside the GI tract || || || ||
The desired response to antimicrobial therapy within the first 24 to 48 hours includes:
|| || || || || || || || || || || || ||
a. increased thirst
|| ||
b. increased sputum production
|| || ||
c. white blood cell count begins to normalize
|| || || || || || ||
d. spike in temperature - ✔✔c. white blood cell count begins to normalize
|| || || || || || || || || || || ||
Most systemic fungal infections are acquired via:
|| || || || || ||
a. oral-fecal transmission
|| ||
b. inhalation
||
c. direct contact
|| || ||
d. nosocomial transmission - ✔✔b. inhalation
|| || || || ||
The ability of an agent to continually suppress growth of an organism after concentrations
|| || || || || || || || || || || || || ||
have decreased to below the minimal inhibitory concentration is known as:
|| || || || || || || || || ||
a. probiotic effect
|| ||
b. postantibiotic effect
|| ||
c. alternative effect
|| ||
MSN 611 Midterm Exam Questions with precise answers
|| || || || || || ||
Eosinophils, neutrophils, and T cells contain the type of histamine receptors referred to as:
|| || || || || || || || || || || || ||
a. H1
||
b. H2
||
c. H3
||
d. H4 - ✔✔d. H4
|| || || ||
Some 1st generation antihistamines are used to treat
|| || || || || || ||
a. as stimulants
|| ||
b. to prevent motion sickness
|| || || ||
c. as anticonvulsants
|| ||
d. as laxatives - ✔✔b. to prevent motion sickness
|| || || || || || || ||
2nd generation antihistamines are preferred for treating which patient category?
|| || || || || || || || ||
a. children
||
b. women
||
c. patients with hypertension
|| || || ||
d. patients with insomnia - ✔✔a. children
|| || || || || ||
Compared to 1st generation antihistamines, 2nd generation antihistamines:
|| || || || || || ||
,2
a. are less able to penetrate the blood brain barrier
|| || || || || || || || ||
b. have fewer muscarinic effects
|| || || ||
c. have greater anticholinergic effects
|| || || ||
d. are more likely to cause drowsiness - ✔✔a. are less able to penetrate the blood brain
|| || || || || || || || || || || || || || || || ||
barrier
Which types of antihistamines are used to inhibit the secretion of gastric acid in patients
|| || || || || || || || || || || || || || ||
with gastrointestinal disorders?
|| ||
a. H1
||
b. H2
||
c. H3
||
d. H4 - ✔✔b. H2
|| || || ||
Under what two circumstances may 2nd generation antihistamines cause drowsiness?
|| || || || || || || || ||
a. if used concurrently with medications that cause CNS depression or with alcohol
|| || || || || || || || || || || ||
b. if used concurrently with medications that cause CNS depression
|| || || || || || || || ||
c. if they are taken with OTC medications
|| || || || || || ||
d. if they are taken with alcohol - ✔✔a. if used concurrently with medications that cause
|| || || || || || || || || || || || || || || ||
CNS depression or with alcohol
|| || || ||
Why is it important for antiviral compounds to be able to discriminate between host and
|| || || || || || || || || || || || || || ||
viral functions with a high degree of specificity?
|| || || || || || ||
a. available antiviral agents mainly target stages in the viral life cycle
|| || || || || || || || || || ||
,2
b. to avoid attacking host cells, since viruses replicate intracellularly and often use host cell
|| || || || || || || || || || || || || || ||
enzymes, macromolecules, and organelles to make their own particles
|| || || || || || || || ||
c. in recent years the demand for new antiviral strategies has increased marketably - ✔✔b.
|| || || || || || || || || || || || || || ||
to avoid attacking host cells, since viruses replicate intracellularly and often use host cell
|| || || || || || || || || || || || || ||
enzymes, macromolecules, and organelles to make their own particles
|| || || || || || || ||
Which of the following statements pertains to antimicrobial therapy?
|| || || || || || || ||
a. lower dosage levels of antimicrobial therapy can help prevent allergic responses
|| || || || || || || || || || ||
b. a differential diagnosis should indicate whether an infection is self-limiting
|| || || || || || || || || || ||
c. self-limiting infections often require antimicrobial therapy
|| || || || || ||
d. in cases of sepsis, laboratory specimens are not required - ✔✔b. a differential diagnosis
|| || || || || || || || || || || || || || ||
should indicate whether an infection is self-limiting
|| || || || || ||
Chose the correct statement describing antibacterial drugs:
|| || || || || ||
a. antibiotics are developed to have similar required exposure times across drug classes
|| || || || || || || || || || || ||
b. Penicillinase-resistant penicillins are the agents of choice for most staphylococcal disease
|| || || || || || || || || || ||
c. narrow therapeutic agents have a higher safety tolerance for large fluctuations of drug in
|| || || || || || || || || || || || || || ||
the blood
||
d. therapeutic levels of antibacterial agents are established during tissue culture studies -
|| || || || || || || || || || || || ||
✔✔b. Penicillinase-resistant penicillins are the agents of choice for most staphylococcal
|| || || || || || || || || || ||
disease
The available modes of action of antihelmintic drugs is/are:
|| || || || || || || ||
a. excrete in the intestine
|| || || ||
, 2
b. locally within the gut lumen to cause expulsion of worms from the GI tract and
|| || || || || || || || || || || || || || || ||
systemically against helminths residing outside the GI tract || || || || || || ||
c. is likely present in virtually every mammal residing in a "natural" habitat
|| || || || || || || || || || || ||
d. systemically against helminths residing outside the GI tract - ✔✔b. locally within the gut
|| || || || || || || || || || || || || || ||
lumen to cause expulsion of worms from the GI tract and systemically against helminths
|| || || || || || || || || || || || || ||
residing outside the GI tract || || || ||
The desired response to antimicrobial therapy within the first 24 to 48 hours includes:
|| || || || || || || || || || || || ||
a. increased thirst
|| ||
b. increased sputum production
|| || ||
c. white blood cell count begins to normalize
|| || || || || || ||
d. spike in temperature - ✔✔c. white blood cell count begins to normalize
|| || || || || || || || || || || ||
Most systemic fungal infections are acquired via:
|| || || || || ||
a. oral-fecal transmission
|| ||
b. inhalation
||
c. direct contact
|| || ||
d. nosocomial transmission - ✔✔b. inhalation
|| || || || ||
The ability of an agent to continually suppress growth of an organism after concentrations
|| || || || || || || || || || || || || ||
have decreased to below the minimal inhibitory concentration is known as:
|| || || || || || || || || ||
a. probiotic effect
|| ||
b. postantibiotic effect
|| ||
c. alternative effect
|| ||
