Questions And Correct Answers (Verified Answers)
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Anti phagocyte
-difficult to eat
-eating of a cell
-important for many diseases
-uniqueness makes it decent vaccine
-ex: HIB, pneumosax, prevnar, menactra
Flagella (external structure)
-long, flexible motor structure
-more you have the more mobile you are
-runs and tumbles
Endoflagella
integrated into membrane
,Pili (external structure)
-long/hollow tube like protein that transport DNA
-minor attachment use
Fimbriae (external structure)
small/bristlelike fibers, mostly protein
-very sticky/ makes for solid attachment
Cell Membrane (interaction point for host cells)
lipid bilayer with proteins
Cell Wall (interaction point for host cells)
made of lipids, proteins and sugars and provides support
,Peptidoglycan (PPG)
-polymer of sugars and amino acids
-provides support to membrane and wall
-found in gram positive (thick) AND gram negative (thin)
-antibiotics based on this
NAG & NAM
-most common sugars in PPG
Gram-positive
-ONE lipid membrane surrounded by THICK cell wall of PPG
-teichoic acids: stabilizes cell wall to make stronger/ heavily cross linked
Gram-negative
-TWO lipid membranes with space between
-no teichoic acids
, D-alanine
-give to gram-positive; kills bacteria
-give to gram-negative; doesn't do anything
Gram-not-applicable
-does not make PPG, antibiotics won't work on these
-cell wall built on other things (lipids) since no PPG
Gram Staining
-uses colored chemical dyes that bind to PPG showing differences in
architecture
-Gram-positive=purple
-Gram-negative=red
Gram stain colors
1. Crystal violet - binds PPG
2. Iodine- crosslink PPG + C6, strong reaction in gram + weak in gram -
3. EtOH- remove weak bond CV, decolorizes gram - leave gram +
purple 4 Safrain- makes gram - visible as red/pink