MH701 Review Final FNU – 3 Exam with accurate detailed
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solutions
compulsive drug craving and use, despite adverse consequences - ✔✔Addiction
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A maladaptive pattern of substance use with tolerance, withdrawal, and persistent desire to
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obtain? - ✔✔Substance dependence
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Educating patient on low-risk drinking - ✔✔men no more than 4 drinks on one occasion or
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14 drinks per week
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women no more than 3 drinks on one occasion or 7 drinks/week
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Deficiency leading to decrease mental functioning, weakness, ataxia, and nystagmus? -
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✔✔Thiamine B1 - Wernickle encephalopathy || || || ||
Pt. presents restless, increased HR, BP, and dilated pupils. Intoxication of what substance? -
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✔✔Stimulants
Most often cause of death with use of ecstasy (MDMA)? - ✔✔Dehydration & Hyperthermia
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Insomnia, running nose, diaphoresis, muscle aches, nausea, chills, fever are S/S of
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withdrawal from what? - ✔✔Opioids - Heroin || || || || || ||
Mu opioid receptor that blocks the effects of opioids while suppressing withdrawal
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symptoms? - ✔✔Methadone || ||
,2
Does NOT stimulant mu receptors, it just blocks them from being capable of stimulation? -
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✔✔Naltrexone
Aversion therapy medication that treats chronic alcoholism? - ✔✔Disulfiram
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Inhibits the reuptake of dopamine and norephinephrine to treat ADHD? -
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✔✔Methlyphenidate
A prodrug activated by lysine portion of molecule by enzymes resulting in gradual release of
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drug? - ✔✔Lisdexamphetamine
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Approved for ADHD and binge eating, also good for those with a history of drug abuse who
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are adults with ADHD? - ✔✔Lisdexamphetamine
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Norepinephrine reuptake inhibitor - first non-stimulant approved by FDA for ADHD tx. || || || || || || || || || || || ||
(inhibits presynaptic norepinephrine transport) - ✔✔Atomoxetine
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reduced hyperactivity and/or impulsivity, also used for Tic disorder and Tourette's? -
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✔✔Alfa-adrenergic agonists || ||
eg. Clonidine, Guanfacine
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Child on Adderall seems more irritable and emotional in afternoon. What is causing it?
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What could you do? - ✔✔Add additional short-acting dose in afternoon, change to long
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acting (would be first option), add adjunctive dose of alfa-adrenergic agonist
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Rapid onset, hours to weeks duration, fluctuating attention, impaired recent & immediate
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memory? - ✔✔Delirium || ||
, 2
Reduce inactivation acetylcholine & thus potentiate cholinergic neurotransmitter for
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memory? - ✔✔Donepezil || ||
Produces effect by blockade of NMDA receptors - indicated for moderate to severe memory?
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- ✔✔Memantine
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Benzo options - elderly that has no active metabolites, half-lives that do not increases with
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age? - ✔✔Lorazepam
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Often avoided in elderly due to significant orthostatic hypotension and anti-cholinergic
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effects? - ✔✔TCA's || ||
Two TCA's are more tolerable for the elderly? - ✔✔Desipramine & nortiptyline
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Called pleasure chemical, too much schizophrenia, to little depression? - ✔✔Dopamine
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Plays tole in mood, anxiety, sleep and appetite, too little associated with depression? -
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✔✔Serotonin
What is the expected time most anti-depressants take to exert significant effect? - ✔✔4-6
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wks
Citalopram is an example of what class antidepressants? - ✔✔SSRI || || || || || || || || ||
SSRI with one of the longest half-lives? - ✔✔Fluoxetine
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SSRI with the shortest half life? - ✔✔Paroxetine
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