1-194 of 194
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Intrinsic regulation: Myogenic
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: when smooth muscle is stretched, it contracts
(if high systemic BP- areterioles constrict)
e.g. standing: high arterial BP in feet (gravity), arterioles
constrict, decrease flow into capillaries
: low arterial BP in. Brain (gravity), arterioles
dilate, increase flow into capillaries
Extrinsic Neural regulation (SNS)
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, : arterial vasoconstriction (except in brain - intrinsic regulation only)
: vasodilation due to low SNS signals (only important PSNS effect = dilation
of arterioles of penis/clitoris)
: also venoconstriction
Process involved in Hemostasis
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I. Vascular spasms
II. Platelet plug formation
III. Clot formation
IV. Clot retraction + repair
V. Fibrinolysis
Air Exchange
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I. Pulmonary Ventilation
II. External Respiration
III. Internal Respiration
Vascular shock
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, : blood volume is normal, but vessels are expanded due to syemic
vasodilation of blood vessels - low BP
Ventricular Myocardial APs:
Repol
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: Ca++ channels close
: K+ voltage gated channels open, high K+ outflux, MP goest to resting
Artificial pacemakers
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: stim. if SA or AV nodes damaged
: if conduction system is damaged, next fastest becomes the pacemaker (if
SA node is damaged, AV node takes over; atria may not contract +
ventricles contract at AV speed = 50bpm)
Septic shock
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: due to bacterial toxins
, Chemicals released when TH is activated during an Immune response
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I. CELL MEDIATED IMMUNITY
: Cytotoxic T- lymphocytes - proliferates + directly destroy: cells containing
virus; cells altered by cancer; or transplanted organs
II. HUMORAL (aB MEDIATED) IMMUNITY
: cells - proliferate and convert to plasma cells - Antibody
Hypovolemic shock
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: low blood pressure due to blood loss, severe burns, diarrhea, vomitting
Ventricular Myocardial APs:
Depol
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: Na+ voltage gates open (fast) = same gates as neuron, skeletal muscle
: MP to -30mV
Significance of O2 - Hb dissociation curve
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