Pharmacology Nursing 1 Pharmacology Nursing.pdf
What are the major functions of the α1 receptor? Increase vascular smooth muscle contraction, increase pupillary dilator
muscle contraction (mydriasis), increase intestinal and bladder sphincter
muscle contraction
What are the major functions of the α2 receptor? Decrease sympathetic outflow, decrease insulin release, decrease lipolysis,
increase platelet aggregation, decrease aqueous humor production
Page 1 of 29 1 of 29 Page 1
,Pharmacology Nursing 2 Pharmacology Nursing.pdf
What are the major functions of the β1 receptor? Increase heart rate, increase contractility, increase renin release, increase
lipolysis
What are the major functions of the β2 receptor? Vasodilation, bronchodilation, increase lipolysis, increase insulin release,
decrease uterine tone (tocolysis), ciliary muscle relaxation, increase aqueous
humor production
What are the major functions of the M1 receptor? CNS, enteric nervous system
Page 2 of 29 2 of 29 Page 2
, Pharmacology Nursing 3 Pharmacology Nursing.pdf
What are the major functions of the M2 receptor? Decrease heart rate and contractility of atria
What are the major functions of the M3 receptor? Increase exocrine gland secretions (e.g., lacrimal, salivary, gastric acid),
increase gut peristalsis, increase bladder contraction, increase
bronchoconstriction, pupillary sphincter muscle contraction (miosis), ciliary
muscle contraction (accommodation)
What are the major functions of the D1 receptor? Relaxes renal vascular smooth muscle
Page 3 of 29 3 of 29 Page 3
What are the major functions of the α1 receptor? Increase vascular smooth muscle contraction, increase pupillary dilator
muscle contraction (mydriasis), increase intestinal and bladder sphincter
muscle contraction
What are the major functions of the α2 receptor? Decrease sympathetic outflow, decrease insulin release, decrease lipolysis,
increase platelet aggregation, decrease aqueous humor production
Page 1 of 29 1 of 29 Page 1
,Pharmacology Nursing 2 Pharmacology Nursing.pdf
What are the major functions of the β1 receptor? Increase heart rate, increase contractility, increase renin release, increase
lipolysis
What are the major functions of the β2 receptor? Vasodilation, bronchodilation, increase lipolysis, increase insulin release,
decrease uterine tone (tocolysis), ciliary muscle relaxation, increase aqueous
humor production
What are the major functions of the M1 receptor? CNS, enteric nervous system
Page 2 of 29 2 of 29 Page 2
, Pharmacology Nursing 3 Pharmacology Nursing.pdf
What are the major functions of the M2 receptor? Decrease heart rate and contractility of atria
What are the major functions of the M3 receptor? Increase exocrine gland secretions (e.g., lacrimal, salivary, gastric acid),
increase gut peristalsis, increase bladder contraction, increase
bronchoconstriction, pupillary sphincter muscle contraction (miosis), ciliary
muscle contraction (accommodation)
What are the major functions of the D1 receptor? Relaxes renal vascular smooth muscle
Page 3 of 29 3 of 29 Page 3
