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NURS 6501 ADVANCED PATHOPHYSIOLOGY
WALDEN UNIVERSITY MIDTERM VERIFIED EXAM
COMPLETE QUESTIONS AND VERIFIED SOLUTIONS
LATEST UPDATE THIS YEAR||NEWEST EXAM!!!
A young adult patient has just been diagnosed with Von
Willebrand disease. Which of the following statements
should you make to advise the patient of potential
consequences of this disease?
A. You may need an allogeneic bone marrow transplant
B. You may have excessive bleeding following tooth
extraction
C. A splenectomy may be necessary to control the disease
D. Expect increasing difficulties with joint mobility -
Answer-You may have excessive bleeding following tooth
extraction
Low dose aspirin is commonly used to reduce the risk of
arterial thrombosis in patients who have suffered a
myocardial infarction. Which one of the following steps in
homeostasis is inhibited by aspirin?
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A. Synthesis of von Willebrand factor
B. Aggregation of platelets
C. Activation of factor Xa
D. Synthesis of antithrombin III - Answer-Aggregation of
platelets
A 24-year-old presents to the office with fatigue. On
physical exam, the NP notices that she ispale with the
following vital signs: HR 112, BP 98/64, resp 20, O2 sats
99%. Her CBC shows: WBC6,000, Hemoglobin 9.6,
Hematocrit 30.2, MCV is decreased at 76. What is the
mostly likely causeof this patient's anemia?
A. Iron deficiency anemia caused by menstruation
B. Beta Thalassemia of genetic origin
C. Pernicious anemia caused by dietary deficiency
D. Folate deficiency caused by alcoholism - Answer-Iron
deficiency anemia caused by menstruation
A 65-year-old female presents to your office complaining
of fatigue. She has a long of rheumatoid arthritis. A CBC
reveals the following: Hgb=11.6 g/dL, Hct=34.8%,
MCV=87 fL/red cell, platelet count of 268,000/microliter,
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and WBC count of 6800/microliter. The serum haptoglobin
level is normal, and the serum iron concentration is 20
micrograms/dL. The total iron binding capacity is 195
micrograms/dL, and the percent saturation is 10.2. The
serum ferritin concentration is 317 ng/mL. No fibrin split
products are detected. The reticulocyte concentration is
1.1%. What is the most likely diagnosis?
A. Beta- thalassemia major
B. Anemia of chronic disease
C. Acute blood loss anemia
D. Iron deficiency anemia - Answer-Anemia of chronic
disease
A 14-year-old male presents with high fever for ten days.
Physical examination reveals scattered petechial
hemorrhages but is negative for enlargement of the liver or
spleen or lymph nodes. Bone marrow examination does
not show any abnormal cells. The complete blood count
(CBC) demonstrates a hemoglobin concentration (HgB) of
13.2 g/dL, hematocrit (Hct) of 38.9%, mean cell volume
(MCV) of 93 fL, platelet count of 175,000/microliter, and
white blood cell (WBC) count of 1850/microliter, with the
differential count showing 1 segmented neutrophil, 98
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lymphocytes, and 1 monocyte per 100 WBCs. What is the
most likely cause of these findings?
A. Overwhelming bacterial infection
B. Acute lymphocytic (or lymphoblastic) leukemia
C. Acute myeloid leukemia
D. Aplastic anemia - Answer-Overwhelming bacterial
infection
A 4-year-old child appears listless for the last week. He
complains of pain when he is picked up by his mother, and
he is irritable when touching his arms or legs. Several
large ecchymotic lesions have appeared on his right thigh
and left shoulder. A complete blood count reveals a
HgB=10.2, Hct=30.5%, MCV=96fL, platelet count of
45,000/ML, and WBC count of 13,990/ML. Examination of
the peripheral blood smear reveals numerous blasts. The
blasts lack peroxidase-positive granules but do contain
periodic acid-Schiff (PAS)-positive aggregates and stain
positively for TdT. Flow cytometry shows the phenotype of
blasts to be CD19+, CD3-, and sIg-. What is the most
likely diagnosis?
A. Acute lymphoblastic leukemia (ALL)
B. Chronic lymphocytic leukemia (CLL)
NURS 6501 ADVANCED PATHOPHYSIOLOGY
WALDEN UNIVERSITY MIDTERM VERIFIED EXAM
COMPLETE QUESTIONS AND VERIFIED SOLUTIONS
LATEST UPDATE THIS YEAR||NEWEST EXAM!!!
A young adult patient has just been diagnosed with Von
Willebrand disease. Which of the following statements
should you make to advise the patient of potential
consequences of this disease?
A. You may need an allogeneic bone marrow transplant
B. You may have excessive bleeding following tooth
extraction
C. A splenectomy may be necessary to control the disease
D. Expect increasing difficulties with joint mobility -
Answer-You may have excessive bleeding following tooth
extraction
Low dose aspirin is commonly used to reduce the risk of
arterial thrombosis in patients who have suffered a
myocardial infarction. Which one of the following steps in
homeostasis is inhibited by aspirin?
,2|Page
A. Synthesis of von Willebrand factor
B. Aggregation of platelets
C. Activation of factor Xa
D. Synthesis of antithrombin III - Answer-Aggregation of
platelets
A 24-year-old presents to the office with fatigue. On
physical exam, the NP notices that she ispale with the
following vital signs: HR 112, BP 98/64, resp 20, O2 sats
99%. Her CBC shows: WBC6,000, Hemoglobin 9.6,
Hematocrit 30.2, MCV is decreased at 76. What is the
mostly likely causeof this patient's anemia?
A. Iron deficiency anemia caused by menstruation
B. Beta Thalassemia of genetic origin
C. Pernicious anemia caused by dietary deficiency
D. Folate deficiency caused by alcoholism - Answer-Iron
deficiency anemia caused by menstruation
A 65-year-old female presents to your office complaining
of fatigue. She has a long of rheumatoid arthritis. A CBC
reveals the following: Hgb=11.6 g/dL, Hct=34.8%,
MCV=87 fL/red cell, platelet count of 268,000/microliter,
,3|Page
and WBC count of 6800/microliter. The serum haptoglobin
level is normal, and the serum iron concentration is 20
micrograms/dL. The total iron binding capacity is 195
micrograms/dL, and the percent saturation is 10.2. The
serum ferritin concentration is 317 ng/mL. No fibrin split
products are detected. The reticulocyte concentration is
1.1%. What is the most likely diagnosis?
A. Beta- thalassemia major
B. Anemia of chronic disease
C. Acute blood loss anemia
D. Iron deficiency anemia - Answer-Anemia of chronic
disease
A 14-year-old male presents with high fever for ten days.
Physical examination reveals scattered petechial
hemorrhages but is negative for enlargement of the liver or
spleen or lymph nodes. Bone marrow examination does
not show any abnormal cells. The complete blood count
(CBC) demonstrates a hemoglobin concentration (HgB) of
13.2 g/dL, hematocrit (Hct) of 38.9%, mean cell volume
(MCV) of 93 fL, platelet count of 175,000/microliter, and
white blood cell (WBC) count of 1850/microliter, with the
differential count showing 1 segmented neutrophil, 98
, 4|Page
lymphocytes, and 1 monocyte per 100 WBCs. What is the
most likely cause of these findings?
A. Overwhelming bacterial infection
B. Acute lymphocytic (or lymphoblastic) leukemia
C. Acute myeloid leukemia
D. Aplastic anemia - Answer-Overwhelming bacterial
infection
A 4-year-old child appears listless for the last week. He
complains of pain when he is picked up by his mother, and
he is irritable when touching his arms or legs. Several
large ecchymotic lesions have appeared on his right thigh
and left shoulder. A complete blood count reveals a
HgB=10.2, Hct=30.5%, MCV=96fL, platelet count of
45,000/ML, and WBC count of 13,990/ML. Examination of
the peripheral blood smear reveals numerous blasts. The
blasts lack peroxidase-positive granules but do contain
periodic acid-Schiff (PAS)-positive aggregates and stain
positively for TdT. Flow cytometry shows the phenotype of
blasts to be CD19+, CD3-, and sIg-. What is the most
likely diagnosis?
A. Acute lymphoblastic leukemia (ALL)
B. Chronic lymphocytic leukemia (CLL)
