NSG 6005 Final Exam Comprehensive Review
Test Bank with 300 Real Test Questions and
Correct Answers with Rationales/ NSG 6005
Advanced Pharmacology Final Exam 2026-2027
1. Long-acting beta-agonists received a black box warning from the US Food and
Drug Administration due to the:
A. Risk of life-threatening dermatological reactions
B. Increased incidence of cardiac events when long-acting beta-agonists are used
C. Increased risk of asthma-related deaths when long-acting beta-agonists are used
D. Risk for life-threatening alterations in electrolytes
Correct answer: C
Rationale: LABA monotherapy in asthma increases risk of asthma-related death;
must be used with an inhaled corticosteroid.
2. Prior to prescribing metformin, the provider should:
A. Draw a serum creatinine to assess renal function.
B. Try the patient on insulin.
C. Tell the patient to increase iodine intake.
D. Have the patient stop taking any sulfonylurea to avoid dangerous drug
interactions.
Correct answer: A
Rationale: Metformin is contraindicated if eGFR <30; renal function must be
assessed before starting.
3. Chemical dependency assessment is integral to the initial assessment of chronic
pain. Which of the following raises a "red flag" about potential chemical
dependency?
A. Use of more than one drug to treat the pain
B. Multiple times when prescriptions are lost with requests to refill
1
,C. Preferences for treatments that include alternative medicines
D. Presence of a family member who has abused drugs
Correct answer: B
Rationale: Frequent lost prescriptions and requests for early refills are classic red
flags for potential chemical dependency or diversion.
4. When a patient is on selective-serotonin reuptake inhibitors:
A. The complete blood count must be monitored every three to four months
B. Therapeutic blood levels must be monitored every six months after a steady
state is achieved
C. Blood glucose must be monitored every three to four months
D. There is no laboratory monitoring required
Correct answer: D
Rationale: SSRIs do not require routine laboratory monitoring unless specific
risks are present (e.g., age, other meds). No standard lab monitoring is indicated.
5. Prescribing for women during their childbearing years requires constant
awareness of the possibility of:
A. Pregnancy unless the women is on birth control
B. Risk for silent bacterial or viral infections of the genitalia
C. High risk for developmental disorders in their infants
D. Decreased risk for abuse during this time
Correct answer: B
Rationale: Silent infections (e.g., chlamydia, gonorrhea, BV) are common and can
affect pregnancy outcomes; awareness is essential when prescribing.
6. The DEA:
A. Registers manufacturers and prescribes controlled substances
B. Regulates NP prescribing at the state level
C. Sanctions providers who prescribe drugs off-label
D. Provides prescribers with a number they can use for insurance billing
2
,Correct answer: A
Rationale: The DEA registers manufacturers and issues DEA numbers to
prescribers of controlled substances.
7. Cecilia presents with depression associated with complaints of fatigue, sleeping
all the time, and lack of motivation. An appropriate initial antidepressant for her
would be:
A. Fluoxetine (Prozac)
B. Paroxetine (Paxil)
C. Amitriptyline (Elavil)
D. Duloxetine (Cymbalta)
Correct answer: D
Rationale: Duloxetine is an SNRI that can help with fatigue and lack of
motivation; it is also effective for pain if present.
8. Sarah, a forty-two-year-old female, requests a prescription for an anorexiant to
treat her obesity. A trial of phentermine is prescribed. Prescribing precautions
include understanding that:
A. Obesity is a contraindication to prescribing phentermine.
B. Anorexiants may cause tolerance and should only be prescribed for six months.
C. Patients should be monitored for postural hypotension.
D. Renal function should be monitored closely while the patient is on anorexiants.
Correct answer: B
Rationale: Phentermine is approved only for short-term use (up to 12 weeks,
typically 6 months due to tolerance and dependence risk).
9. Patients with psychiatric illnesses have adherence rates to their drug regimen
between 35% and 60%. To improve adherence in this population, prescribe drugs:
A. With a longer half-life so that missed doses produce a longer taper on the drug
curve
B. In oral formulations that are more easily taken
C. That do not require frequent monitoring
3
, D. Combined with patient education about the need to adhere even when
symptoms are absent
Correct answer: A
Rationale: Longer half-life drugs provide a buffer against missed doses, reducing
withdrawal or relapse risk.
10. The drugs recommended by the American Academy of Pediatrics for use in
children with diabetes (depending upon type of diabetes) are:
A. Metformin and insulin
B. Sulfonylureas and insulin glargine
C. Split-mixed dose insulin and GLP-1 agonists
D. Biguanides and insulin lispro
Correct answer: A
Rationale: For type 1: insulin; for type 2: metformin and insulin are AAP-
recommended.
11. Inadequate vitamin D intake can contribute to the development of osteoporosis
by:
A. Increasing calcitonin production
B. Increasing calcium absorption from the intestine
C. Altering calcium metabolism
D. Stimulating bone formation
Correct answer: C
Rationale: Vitamin D deficiency alters calcium metabolism by reducing intestinal
calcium absorption, leading to bone loss.
12. Which of the following is the goal of treatment of acute pain?
A. Pain at a tolerable level where patient may return to activities of daily living
B. Reduction of pain with a minimum of drug adverse effects
C. Reduction or elimination of pain with minimum adverse reactions
D. Adequate pain relief without constipation or nausea from the drugs
4
Test Bank with 300 Real Test Questions and
Correct Answers with Rationales/ NSG 6005
Advanced Pharmacology Final Exam 2026-2027
1. Long-acting beta-agonists received a black box warning from the US Food and
Drug Administration due to the:
A. Risk of life-threatening dermatological reactions
B. Increased incidence of cardiac events when long-acting beta-agonists are used
C. Increased risk of asthma-related deaths when long-acting beta-agonists are used
D. Risk for life-threatening alterations in electrolytes
Correct answer: C
Rationale: LABA monotherapy in asthma increases risk of asthma-related death;
must be used with an inhaled corticosteroid.
2. Prior to prescribing metformin, the provider should:
A. Draw a serum creatinine to assess renal function.
B. Try the patient on insulin.
C. Tell the patient to increase iodine intake.
D. Have the patient stop taking any sulfonylurea to avoid dangerous drug
interactions.
Correct answer: A
Rationale: Metformin is contraindicated if eGFR <30; renal function must be
assessed before starting.
3. Chemical dependency assessment is integral to the initial assessment of chronic
pain. Which of the following raises a "red flag" about potential chemical
dependency?
A. Use of more than one drug to treat the pain
B. Multiple times when prescriptions are lost with requests to refill
1
,C. Preferences for treatments that include alternative medicines
D. Presence of a family member who has abused drugs
Correct answer: B
Rationale: Frequent lost prescriptions and requests for early refills are classic red
flags for potential chemical dependency or diversion.
4. When a patient is on selective-serotonin reuptake inhibitors:
A. The complete blood count must be monitored every three to four months
B. Therapeutic blood levels must be monitored every six months after a steady
state is achieved
C. Blood glucose must be monitored every three to four months
D. There is no laboratory monitoring required
Correct answer: D
Rationale: SSRIs do not require routine laboratory monitoring unless specific
risks are present (e.g., age, other meds). No standard lab monitoring is indicated.
5. Prescribing for women during their childbearing years requires constant
awareness of the possibility of:
A. Pregnancy unless the women is on birth control
B. Risk for silent bacterial or viral infections of the genitalia
C. High risk for developmental disorders in their infants
D. Decreased risk for abuse during this time
Correct answer: B
Rationale: Silent infections (e.g., chlamydia, gonorrhea, BV) are common and can
affect pregnancy outcomes; awareness is essential when prescribing.
6. The DEA:
A. Registers manufacturers and prescribes controlled substances
B. Regulates NP prescribing at the state level
C. Sanctions providers who prescribe drugs off-label
D. Provides prescribers with a number they can use for insurance billing
2
,Correct answer: A
Rationale: The DEA registers manufacturers and issues DEA numbers to
prescribers of controlled substances.
7. Cecilia presents with depression associated with complaints of fatigue, sleeping
all the time, and lack of motivation. An appropriate initial antidepressant for her
would be:
A. Fluoxetine (Prozac)
B. Paroxetine (Paxil)
C. Amitriptyline (Elavil)
D. Duloxetine (Cymbalta)
Correct answer: D
Rationale: Duloxetine is an SNRI that can help with fatigue and lack of
motivation; it is also effective for pain if present.
8. Sarah, a forty-two-year-old female, requests a prescription for an anorexiant to
treat her obesity. A trial of phentermine is prescribed. Prescribing precautions
include understanding that:
A. Obesity is a contraindication to prescribing phentermine.
B. Anorexiants may cause tolerance and should only be prescribed for six months.
C. Patients should be monitored for postural hypotension.
D. Renal function should be monitored closely while the patient is on anorexiants.
Correct answer: B
Rationale: Phentermine is approved only for short-term use (up to 12 weeks,
typically 6 months due to tolerance and dependence risk).
9. Patients with psychiatric illnesses have adherence rates to their drug regimen
between 35% and 60%. To improve adherence in this population, prescribe drugs:
A. With a longer half-life so that missed doses produce a longer taper on the drug
curve
B. In oral formulations that are more easily taken
C. That do not require frequent monitoring
3
, D. Combined with patient education about the need to adhere even when
symptoms are absent
Correct answer: A
Rationale: Longer half-life drugs provide a buffer against missed doses, reducing
withdrawal or relapse risk.
10. The drugs recommended by the American Academy of Pediatrics for use in
children with diabetes (depending upon type of diabetes) are:
A. Metformin and insulin
B. Sulfonylureas and insulin glargine
C. Split-mixed dose insulin and GLP-1 agonists
D. Biguanides and insulin lispro
Correct answer: A
Rationale: For type 1: insulin; for type 2: metformin and insulin are AAP-
recommended.
11. Inadequate vitamin D intake can contribute to the development of osteoporosis
by:
A. Increasing calcitonin production
B. Increasing calcium absorption from the intestine
C. Altering calcium metabolism
D. Stimulating bone formation
Correct answer: C
Rationale: Vitamin D deficiency alters calcium metabolism by reducing intestinal
calcium absorption, leading to bone loss.
12. Which of the following is the goal of treatment of acute pain?
A. Pain at a tolerable level where patient may return to activities of daily living
B. Reduction of pain with a minimum of drug adverse effects
C. Reduction or elimination of pain with minimum adverse reactions
D. Adequate pain relief without constipation or nausea from the drugs
4
