NEU 201 Final Exam UPDATED ACTUAL
Questions and CORRECT Answers
Most neurons are post mitotic. True or False? - CORRECT ANSWER - True
Golgi's reticular theory contends that - CORRECT ANSWER - Neurons are not individual, separate
cells
Where do action potentials start? - CORRECT ANSWER - Axon initial segment
What type of cells make myelin in the CNS? - CORRECT ANSWER - Oligodendrocyte cells
What contributes to the direction of action potential propagation? - CORRECT ANSWER - Site of
action potential initiation and sodium channel kinetics
Potassium flowing out of a cell would have what effect on the membrane potential? - CORRECT
ANSWER - Make it more negative
If membrane resistance increases - CORRECT ANSWER - the length constant increases and the
time constant increases
In the ball and chain model of voltage-gated Na+ channel, the ball is responsible for - CORRECT
ANSWER - Na+ channels closing
Mammalian neocortex is organized into - CORRECT ANSWER - layers
A given neurotransmitter can have more than one receptor. True or False? - CORRECT
ANSWER - True
You are recording from a cell in the eye that id responsive to light. Which feature of that cell's spikes is
likely to change with a stronger or weaker light? - CORRECT ANSWER - Frequency
,Which kind of plasticity occurs during high frequency stimulation at synapses with a high probability of
neurotransmitter release? - CORRECT ANSWER - Depression
Which contributes to the negative resting potential? - CORRECT ANSWER - K+ leak channels,
intracellular K+ concentration, K+ valence, K+ permeability
The Cl- reversal potential is -70 mV. If Vrest is -70 mV, what happens to the membrane potential if Cl-
channels open? - CORRECT ANSWER - No change
What effect does decreasing extracellular Na+ have on action potential amplitude? - CORRECT
ANSWER - Decrease
Because of spatial summation and passive conduction properties, inputs that are closer to the area where
action potentials are generated will have more or less effect on the neurons ability to reach threshold? -
CORRECT ANSWER - more
To calculate equilibrium potential of a single ion you need to know.. - CORRECT ANSWER - the
concentration of that ion inside the cell
The spinal cord is part of the peripheral nervous system. True or False? - CORRECT ANSWER -
False
What happens when you change permeability during the action potential? - CORRECT ANSWER -
PNa increases rapidly, PK rises slowly
Chemical synapses - CORRECT ANSWER - involve the release of neurotransmitter
Electrical synapses - CORRECT ANSWER - are typically bidirectional and are faster than
chemical synapses
What cellular feature is responsible for conductance? - CORRECT ANSWER - Ion channels
, Gray matter is myelinated axons. True or False? - CORRECT ANSWER - False
Chemical synapses can transmit - CORRECT ANSWER - depolarizing and hyperpolarizing signals
How does decreasing extracellular Ca2+ affect neurotransmitter release? - CORRECT ANSWER -
Decrease
Which channels are responsible for the after-hyperpolarizing? - CORRECT ANSWER - K+ leak
channels and delayed rectifiers
A drug that blocks the function of SNARES will have what effect on synaptic transmission? - CORRECT
ANSWER - Prevent neurotransmitter release
A drug that blocks acetylcholine receptors is most likely to cause which type of paralysis? - CORRECT
ANSWER - Flacid
During the dendritic integration/summation both excitatory and inhibitory inputs are summed. True or
False? - CORRECT ANSWER - True
What is true about glutamate? - CORRECT ANSWER - most common excitatory neurotransmitter,
precursor for GABA, inhibitory neurotransmitter, opens channels permeable to Na+ and K+
A channel that triggers Na+ flow is what because it causes the membrane to what? - CORRECT
ANSWER - excitatory, depolarize
Being unmyelinated or smaller diameter makes conduction velocity? - CORRECT ANSWER -
slower
How can we prove that a chemical is a neurotransmitter? - CORRECT ANSWER - It is released
from a presynaptic neuron, it is stored in vesicles of a presynaptic neuron, it produces a response in the
postsynaptic neuron that mimics the one in the presynaptic neuron
Questions and CORRECT Answers
Most neurons are post mitotic. True or False? - CORRECT ANSWER - True
Golgi's reticular theory contends that - CORRECT ANSWER - Neurons are not individual, separate
cells
Where do action potentials start? - CORRECT ANSWER - Axon initial segment
What type of cells make myelin in the CNS? - CORRECT ANSWER - Oligodendrocyte cells
What contributes to the direction of action potential propagation? - CORRECT ANSWER - Site of
action potential initiation and sodium channel kinetics
Potassium flowing out of a cell would have what effect on the membrane potential? - CORRECT
ANSWER - Make it more negative
If membrane resistance increases - CORRECT ANSWER - the length constant increases and the
time constant increases
In the ball and chain model of voltage-gated Na+ channel, the ball is responsible for - CORRECT
ANSWER - Na+ channels closing
Mammalian neocortex is organized into - CORRECT ANSWER - layers
A given neurotransmitter can have more than one receptor. True or False? - CORRECT
ANSWER - True
You are recording from a cell in the eye that id responsive to light. Which feature of that cell's spikes is
likely to change with a stronger or weaker light? - CORRECT ANSWER - Frequency
,Which kind of plasticity occurs during high frequency stimulation at synapses with a high probability of
neurotransmitter release? - CORRECT ANSWER - Depression
Which contributes to the negative resting potential? - CORRECT ANSWER - K+ leak channels,
intracellular K+ concentration, K+ valence, K+ permeability
The Cl- reversal potential is -70 mV. If Vrest is -70 mV, what happens to the membrane potential if Cl-
channels open? - CORRECT ANSWER - No change
What effect does decreasing extracellular Na+ have on action potential amplitude? - CORRECT
ANSWER - Decrease
Because of spatial summation and passive conduction properties, inputs that are closer to the area where
action potentials are generated will have more or less effect on the neurons ability to reach threshold? -
CORRECT ANSWER - more
To calculate equilibrium potential of a single ion you need to know.. - CORRECT ANSWER - the
concentration of that ion inside the cell
The spinal cord is part of the peripheral nervous system. True or False? - CORRECT ANSWER -
False
What happens when you change permeability during the action potential? - CORRECT ANSWER -
PNa increases rapidly, PK rises slowly
Chemical synapses - CORRECT ANSWER - involve the release of neurotransmitter
Electrical synapses - CORRECT ANSWER - are typically bidirectional and are faster than
chemical synapses
What cellular feature is responsible for conductance? - CORRECT ANSWER - Ion channels
, Gray matter is myelinated axons. True or False? - CORRECT ANSWER - False
Chemical synapses can transmit - CORRECT ANSWER - depolarizing and hyperpolarizing signals
How does decreasing extracellular Ca2+ affect neurotransmitter release? - CORRECT ANSWER -
Decrease
Which channels are responsible for the after-hyperpolarizing? - CORRECT ANSWER - K+ leak
channels and delayed rectifiers
A drug that blocks the function of SNARES will have what effect on synaptic transmission? - CORRECT
ANSWER - Prevent neurotransmitter release
A drug that blocks acetylcholine receptors is most likely to cause which type of paralysis? - CORRECT
ANSWER - Flacid
During the dendritic integration/summation both excitatory and inhibitory inputs are summed. True or
False? - CORRECT ANSWER - True
What is true about glutamate? - CORRECT ANSWER - most common excitatory neurotransmitter,
precursor for GABA, inhibitory neurotransmitter, opens channels permeable to Na+ and K+
A channel that triggers Na+ flow is what because it causes the membrane to what? - CORRECT
ANSWER - excitatory, depolarize
Being unmyelinated or smaller diameter makes conduction velocity? - CORRECT ANSWER -
slower
How can we prove that a chemical is a neurotransmitter? - CORRECT ANSWER - It is released
from a presynaptic neuron, it is stored in vesicles of a presynaptic neuron, it produces a response in the
postsynaptic neuron that mimics the one in the presynaptic neuron
