NU 578, UNIT 4 - GI DRUGS
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📋 DOCUMENT OVERVIEW 53 Qs
This document, "Nu 578, Unit 4 - GI Drugs," covers specific topics in gastrointestinal pharmacology,
including peptic ulcer disease (PUD), gastroesophageal reflux disease (GERD), acid secretion, histamine
receptor antagonists, corticosteroids, and treatments for conditions such as irritable bowel syndrome
(IBS-D), Crohn's disease, ulcerative colitis, and Clostridioides difficile (C. diff) infection. The document
provides 53 questions with correct answers, allowing students to review and understand key concepts.
This resource can be used for study and exam preparation to reinforce knowledge and fill gaps in
understanding gastrointestinal pharmacology.
✓ Verified Answers ✓ Exam Ready ✓ Study Guide
Trusted by thousands of students and professionals worldwide
EXAM QUESTIONS
QUESTION 1
Treatment Goal for PUD/ GERD
CORRECT ANSWER
•Main treatment goal: neutralization of stomach acid
•Oxyntic glands in stomach secrete acid (parietal cells)
•To get maximum acid secretion, these cells need to be stimulated by gastrin + ACh + histamine
•If any one of these 3 is ↓, acid secretion will be markedly ↓
QUESTION 2
acid secretion
CORRECT ANSWER
- ↑ ACH ↑ gastrin in gut
-Histamine is always available in gut
- when the 3 work together, They stimulate the parietal cells to ↑ HCI secretion.
QUESTION 3
Cimetidine (Tagamet)
CORRECT ANSWER
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, H2 receptor antagonist
- PUD or GERD tx
- Inhibits P450 enzymes.
- Well tolerated, but watch for renal/hepatic tox in older patients.
QUESTION 4
Ranitidine (Zantac)
CORRECT ANSWER
H2 receptor antagonist
- PUD or GERD tx
-Less P450 inhibition—on recall due to contaminant that may cause cancer
QUESTION 5
Famotidine (Pepcid)
CORRECT ANSWER
H2 receptor antagonist
- PUD or GERD tx
- No P450 inhibition
QUESTION 6
Nizatidine (Axid)
CORRECT ANSWER
H2 receptor antagonist
- PUD or GERD tx
- No P450 inhibition—recalled drug
QUESTION 7
Aluminium salts(Remegel)
CORRECT ANSWER
- Antacid
- PUD or GERD tx
- Constipation, hypercalcemia
QUESTION 8
Ca carbonate(Tums)
CORRECT ANSWER
- Antacid
- PUD or GERD tx
- Constipation, hypercalcemia
QUESTION 9
Mg salts(Milk of Magnesia)
CORRECT ANSWER
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Page 2 of 10
50+ (Latest 2026 Edition) 100% Verified Q&A + Answer Key Solutions
100% Guarantee Pass
📋 DOCUMENT OVERVIEW 53 Qs
This document, "Nu 578, Unit 4 - GI Drugs," covers specific topics in gastrointestinal pharmacology,
including peptic ulcer disease (PUD), gastroesophageal reflux disease (GERD), acid secretion, histamine
receptor antagonists, corticosteroids, and treatments for conditions such as irritable bowel syndrome
(IBS-D), Crohn's disease, ulcerative colitis, and Clostridioides difficile (C. diff) infection. The document
provides 53 questions with correct answers, allowing students to review and understand key concepts.
This resource can be used for study and exam preparation to reinforce knowledge and fill gaps in
understanding gastrointestinal pharmacology.
✓ Verified Answers ✓ Exam Ready ✓ Study Guide
Trusted by thousands of students and professionals worldwide
EXAM QUESTIONS
QUESTION 1
Treatment Goal for PUD/ GERD
CORRECT ANSWER
•Main treatment goal: neutralization of stomach acid
•Oxyntic glands in stomach secrete acid (parietal cells)
•To get maximum acid secretion, these cells need to be stimulated by gastrin + ACh + histamine
•If any one of these 3 is ↓, acid secretion will be markedly ↓
QUESTION 2
acid secretion
CORRECT ANSWER
- ↑ ACH ↑ gastrin in gut
-Histamine is always available in gut
- when the 3 work together, They stimulate the parietal cells to ↑ HCI secretion.
QUESTION 3
Cimetidine (Tagamet)
CORRECT ANSWER
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, H2 receptor antagonist
- PUD or GERD tx
- Inhibits P450 enzymes.
- Well tolerated, but watch for renal/hepatic tox in older patients.
QUESTION 4
Ranitidine (Zantac)
CORRECT ANSWER
H2 receptor antagonist
- PUD or GERD tx
-Less P450 inhibition—on recall due to contaminant that may cause cancer
QUESTION 5
Famotidine (Pepcid)
CORRECT ANSWER
H2 receptor antagonist
- PUD or GERD tx
- No P450 inhibition
QUESTION 6
Nizatidine (Axid)
CORRECT ANSWER
H2 receptor antagonist
- PUD or GERD tx
- No P450 inhibition—recalled drug
QUESTION 7
Aluminium salts(Remegel)
CORRECT ANSWER
- Antacid
- PUD or GERD tx
- Constipation, hypercalcemia
QUESTION 8
Ca carbonate(Tums)
CORRECT ANSWER
- Antacid
- PUD or GERD tx
- Constipation, hypercalcemia
QUESTION 9
Mg salts(Milk of Magnesia)
CORRECT ANSWER
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Page 2 of 10
