NRNP 6566 FINAL EXAM 4 2026
PHARMACOLOGY AND CLINICAL GUIDELINES
REVIEW A+
◉ ABCDE. Answer: asymmetry, border, color, diameter >6mm,
evolving
◉ skin eruptions or exanthema 3 groups. Answer: 1. Macular and
maculopapular lesions
2. vesicular or bullous lesions
3. pustular, petechial, or purpuric lesions
◉ secondary changes of skin lesions. Answer: comedones, crusting,
excoriation, lichenification, scales, scarring, telangiectasia
◉ acne. Answer: inflammatory disease of the skin involving the
sebaceous glands and hair follicles
causes: corticosteriods, isoniazid
◉ bullous lesions. Answer: Caused by exfoliative toxins A and B
Have the appearance of wrinkled tissue paper
,Lead to widespread desquamation of the skin
Patients are left vulnerable to secondary bacterial infections
causes: barbiturate overdose, penicillamine, sulfonamides
◉ eczematous dermatitis. Answer: most common inflammatory skin
disorder, several forms including irritant contact dermatitis allergic
contact dermatitis and atopic dermatitis
causes: abx, methyldopa, phenylbutazone, sulfonamides
◉ erythemia multiforme. Answer: Hypersensitivity reaction
characterized by targetoid rash and bullae; *HSV and mycoplasma
infections; EM with oral mucosa and fever is steven-johnson
syndrome
causes: barbiturates, hydantois, penicillin, salicylates, sulfonamides,
sulfonylureas
◉ erythema nodosum. Answer: inflammation of subcutaneous
tissues resulting in tender, erythematous nodules; may be an
abnormal immune response to a systemic disease, an infection, or a
drug
,causes: contraceptives, sulfonamides
◉ exfoliative dermatitis. Answer: a condition in which there is
widespread scaling of the skin, often with pruritus, erythroderma,
and hair loss
causes: allopurinal, gold, indomethacin, phenylbutazone
◉ lichenoid eruption. Answer: violaceous to purple, polygonal
lesions that resemble those seen in lichen planus
Causes: cholorquine, chlorpropamide, mepacrine, quinidine,
quinine, thiazides
◉ photosensitivity. Answer: increased reaction of the skin to
exposure to sunlight
causes: amiodarone, nalidixic acid, sulfonamides, tetracycline
◉ pigmentation. Answer: coloration caused by deposit, or lack, of
colored material in the tissues
causes: chloroquine, heavy metals, mepacrine
, ◉ Psoriasiform rash. Answer: causes: gold, methyldopa
◉ purpura. Answer: multiple pinpoint hemorrhages and
accumulation of blood under the skin
causes: cytotoxic drugs, meprobamate, quinidine, quinine
◉ systemic lupus erythematosus (SLE). Answer: chronic
autoimmune inflammatory disease of collagen in skin, joints, and
internal organs
causes: hydralazine, isoniazid, penicillamine, procainamide
◉ urticaria. Answer: allergic reaction of the skin characterized by
the eruption of pale red, elevated patches called wheals or hives
causes: aspirin, imipramine, penicillin, serum, toxoid, vaccines
◉ Bulla. Answer: a large blister that is usually more than 0.5 cm in
diameter
PHARMACOLOGY AND CLINICAL GUIDELINES
REVIEW A+
◉ ABCDE. Answer: asymmetry, border, color, diameter >6mm,
evolving
◉ skin eruptions or exanthema 3 groups. Answer: 1. Macular and
maculopapular lesions
2. vesicular or bullous lesions
3. pustular, petechial, or purpuric lesions
◉ secondary changes of skin lesions. Answer: comedones, crusting,
excoriation, lichenification, scales, scarring, telangiectasia
◉ acne. Answer: inflammatory disease of the skin involving the
sebaceous glands and hair follicles
causes: corticosteriods, isoniazid
◉ bullous lesions. Answer: Caused by exfoliative toxins A and B
Have the appearance of wrinkled tissue paper
,Lead to widespread desquamation of the skin
Patients are left vulnerable to secondary bacterial infections
causes: barbiturate overdose, penicillamine, sulfonamides
◉ eczematous dermatitis. Answer: most common inflammatory skin
disorder, several forms including irritant contact dermatitis allergic
contact dermatitis and atopic dermatitis
causes: abx, methyldopa, phenylbutazone, sulfonamides
◉ erythemia multiforme. Answer: Hypersensitivity reaction
characterized by targetoid rash and bullae; *HSV and mycoplasma
infections; EM with oral mucosa and fever is steven-johnson
syndrome
causes: barbiturates, hydantois, penicillin, salicylates, sulfonamides,
sulfonylureas
◉ erythema nodosum. Answer: inflammation of subcutaneous
tissues resulting in tender, erythematous nodules; may be an
abnormal immune response to a systemic disease, an infection, or a
drug
,causes: contraceptives, sulfonamides
◉ exfoliative dermatitis. Answer: a condition in which there is
widespread scaling of the skin, often with pruritus, erythroderma,
and hair loss
causes: allopurinal, gold, indomethacin, phenylbutazone
◉ lichenoid eruption. Answer: violaceous to purple, polygonal
lesions that resemble those seen in lichen planus
Causes: cholorquine, chlorpropamide, mepacrine, quinidine,
quinine, thiazides
◉ photosensitivity. Answer: increased reaction of the skin to
exposure to sunlight
causes: amiodarone, nalidixic acid, sulfonamides, tetracycline
◉ pigmentation. Answer: coloration caused by deposit, or lack, of
colored material in the tissues
causes: chloroquine, heavy metals, mepacrine
, ◉ Psoriasiform rash. Answer: causes: gold, methyldopa
◉ purpura. Answer: multiple pinpoint hemorrhages and
accumulation of blood under the skin
causes: cytotoxic drugs, meprobamate, quinidine, quinine
◉ systemic lupus erythematosus (SLE). Answer: chronic
autoimmune inflammatory disease of collagen in skin, joints, and
internal organs
causes: hydralazine, isoniazid, penicillamine, procainamide
◉ urticaria. Answer: allergic reaction of the skin characterized by
the eruption of pale red, elevated patches called wheals or hives
causes: aspirin, imipramine, penicillin, serum, toxoid, vaccines
◉ Bulla. Answer: a large blister that is usually more than 0.5 cm in
diameter
