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# MED SURG 324 – RN PHARMACOLOGY VATI
REEVALUATION ASSESSMENT COMPLETE GUIDE
**ACADEMIC YEAR:** 2026/2027
**COURSE:** MED SURG 324 – PHARMACOLOGY
**ASSESSMENT TYPE:** VATI REEVALUATION /
VIRTUAL ATI PHARMACOLOGY
**TOTAL QUESTIONS:** 115
**FORMAT:** MULTIPLE CHOICE WITH DETAILED
RATIONALES
**TARGET GRADE:** A+ (HIGH YIELD / VERIFIED
CONTENT)
## Exam Structure
This comprehensive guide is organized into **10 content domains**
aligned with the VATI Pharmacology blueprint and NCLEX-RN test
plan for 2026/2027:
| Domain | Topic | Questions |
|--------|-------|-----------|
| Domain 1 | Medication Safety & Adverse Effects | 15 |
,2|Page
| Domain 2 | Cardiovascular Medications | 15 |
| Domain 3 | Endocrine Medications | 12 |
| Domain 4 | Respiratory Medications | 10 |
| Domain 5 | Neurologic & Psychiatric Medications | 12 |
| Domain 6 | Gastrointestinal Medications | 10 |
| Domain 7 | Anti-infectives & Immunizations | 15 |
| Domain 8 | Chemotherapy & Immunomodulators | 8 |
| Domain 9 | Herbal Supplements & Drug Interactions | 8 |
| Domain 10 | Dosage Calculation & Priority Setting | 10 |
| **Total** | | **115** |
## Domain 1: Medication Safety & Adverse Effects (15 Questions)
**Question 1**
A nurse is caring for a client who ingested a toxic amount of
acetaminophen 36 hours ago. For which of the following findings should
the nurse monitor? (Select all that apply)
a) Elevated troponin level
b) **Diaphoresis**
c) Hyperglycemia
d) **Abdominal discomfort**
e) **Increased alanine aminotransferase (ALT) level**
,3|Page
**Rationale:** Acetaminophen toxicity manifests in stages. Early
manifestations (first 24 hours) include diaphoresis, nausea, vomiting,
and abdominal discomfort . Later manifestations (48-72 hours) indicate
liver failure with elevated ALT/AST levels . Troponin elevation is
associated with cardiac injury, not acetaminophen toxicity.
Hyperglycemia is not characteristic; hypoglycemia may occur in late
stages.
**Question 2**
A nurse is providing teaching to a client prescribed ciprofloxacin. What
adverse effect should the nurse include in the teaching?
a) Tendon rupture only
b) **Phototoxicity**
c) Peripheral edema
d) Hypoglycemia
**Rationale:** Ciprofloxacin (a fluoroquinolone) causes phototoxicity,
placing the client at risk for severe sunburn with minimal UV exposure.
Clients should avoid direct sunlight, wear protective clothing and
sunglasses, and discontinue the medication if phototoxicity occurs .
Tendon rupture is another serious adverse effect, but phototoxicity is the
most common sun-related reaction.
**Question 3**
, 4|Page
A nurse is administering diclofenac sodium to a client with chronic
bursitis. Which action should the nurse take?
a) Administer on an empty stomach
b) **Administer the medication with food**
c) Administer with grapefruit juice
d) Administer at bedtime only
**Rationale:** Diclofenac is an NSAID that can cause significant
gastric irritation, including mucosal erosion and ulceration.
Administering with food, milk, or antacids helps reduce gastrointestinal
distress . The medication can be taken without regard to meals for
absorption, but food is recommended for tolerance.
**Question 4**
A nurse is planning care for a client scheduled for surgery with a latex
allergy. Which action should the nurse take?
a) Use powdered gloves for better grip
b) **Place monitoring cords and tubes in a stockinette**
c) Use latex-based adhesive tape
d) Pre-medicate with diphenhydramine only
**Rationale:** Clients with latex allergy require latex-free
environments. Monitoring cords, blood pressure cuffs, and tubes should
be placed in stockinette or wrapped with latex-free materials to prevent
# MED SURG 324 – RN PHARMACOLOGY VATI
REEVALUATION ASSESSMENT COMPLETE GUIDE
**ACADEMIC YEAR:** 2026/2027
**COURSE:** MED SURG 324 – PHARMACOLOGY
**ASSESSMENT TYPE:** VATI REEVALUATION /
VIRTUAL ATI PHARMACOLOGY
**TOTAL QUESTIONS:** 115
**FORMAT:** MULTIPLE CHOICE WITH DETAILED
RATIONALES
**TARGET GRADE:** A+ (HIGH YIELD / VERIFIED
CONTENT)
## Exam Structure
This comprehensive guide is organized into **10 content domains**
aligned with the VATI Pharmacology blueprint and NCLEX-RN test
plan for 2026/2027:
| Domain | Topic | Questions |
|--------|-------|-----------|
| Domain 1 | Medication Safety & Adverse Effects | 15 |
,2|Page
| Domain 2 | Cardiovascular Medications | 15 |
| Domain 3 | Endocrine Medications | 12 |
| Domain 4 | Respiratory Medications | 10 |
| Domain 5 | Neurologic & Psychiatric Medications | 12 |
| Domain 6 | Gastrointestinal Medications | 10 |
| Domain 7 | Anti-infectives & Immunizations | 15 |
| Domain 8 | Chemotherapy & Immunomodulators | 8 |
| Domain 9 | Herbal Supplements & Drug Interactions | 8 |
| Domain 10 | Dosage Calculation & Priority Setting | 10 |
| **Total** | | **115** |
## Domain 1: Medication Safety & Adverse Effects (15 Questions)
**Question 1**
A nurse is caring for a client who ingested a toxic amount of
acetaminophen 36 hours ago. For which of the following findings should
the nurse monitor? (Select all that apply)
a) Elevated troponin level
b) **Diaphoresis**
c) Hyperglycemia
d) **Abdominal discomfort**
e) **Increased alanine aminotransferase (ALT) level**
,3|Page
**Rationale:** Acetaminophen toxicity manifests in stages. Early
manifestations (first 24 hours) include diaphoresis, nausea, vomiting,
and abdominal discomfort . Later manifestations (48-72 hours) indicate
liver failure with elevated ALT/AST levels . Troponin elevation is
associated with cardiac injury, not acetaminophen toxicity.
Hyperglycemia is not characteristic; hypoglycemia may occur in late
stages.
**Question 2**
A nurse is providing teaching to a client prescribed ciprofloxacin. What
adverse effect should the nurse include in the teaching?
a) Tendon rupture only
b) **Phototoxicity**
c) Peripheral edema
d) Hypoglycemia
**Rationale:** Ciprofloxacin (a fluoroquinolone) causes phototoxicity,
placing the client at risk for severe sunburn with minimal UV exposure.
Clients should avoid direct sunlight, wear protective clothing and
sunglasses, and discontinue the medication if phototoxicity occurs .
Tendon rupture is another serious adverse effect, but phototoxicity is the
most common sun-related reaction.
**Question 3**
, 4|Page
A nurse is administering diclofenac sodium to a client with chronic
bursitis. Which action should the nurse take?
a) Administer on an empty stomach
b) **Administer the medication with food**
c) Administer with grapefruit juice
d) Administer at bedtime only
**Rationale:** Diclofenac is an NSAID that can cause significant
gastric irritation, including mucosal erosion and ulceration.
Administering with food, milk, or antacids helps reduce gastrointestinal
distress . The medication can be taken without regard to meals for
absorption, but food is recommended for tolerance.
**Question 4**
A nurse is planning care for a client scheduled for surgery with a latex
allergy. Which action should the nurse take?
a) Use powdered gloves for better grip
b) **Place monitoring cords and tubes in a stockinette**
c) Use latex-based adhesive tape
d) Pre-medicate with diphenhydramine only
**Rationale:** Clients with latex allergy require latex-free
environments. Monitoring cords, blood pressure cuffs, and tubes should
be placed in stockinette or wrapped with latex-free materials to prevent
