C omp le t e R eal Ex am Q u est io ns A n d C orr ec t
A nsw ers ( Ve rif ied A n swer s) A l re ady Gra de d
A + | G uara nt e ed Su cc ess! ! N ewes t Ex am |
Jus t R el eas ed!!
Ch 12 - Cholinergic Drugs Affecting the Autonomic Nervous System
Ch 13 - Adrenergic Drugs Affecting the Autonomic Nervous System
Ch 15 - Drugs for Seizures Ch 20 - Drugs for Degenerative Diseases
of the Nervous System Ch 21 - Drugs for Neuromuscular Disorders
Ch 32 - Drugs for Hematopoietic Disorders Ch 38 - Drugs for
Neoplasia Ch 39 - Drugs for Shock
What is the MOA of donepezil (Aricept)?
Increases the amount of acetylcholine (ACh) by inhibiting
acetylcholinesterase (AChE)
What is the indication of acetylcholinesterase (AChE)/cholinesterase
inhibitors?
Alzheimer's disease
What is the indication of bethanechol (Urecholine)?
Urinary retention
What is the MOA of bethanechol (Urecholine)?
Binds to cholinergic receptors to produce the rest-and-digest response
that relaxes the bladder
,What is a cholinergic crisis?
Symptoms that occur when a patient is given too much cholinergic medication
What are symptoms of a cholinergic crisis?
Salivation
Lacrimation
Urination
Defecation
Gastrointestinal distress
Emesis
What is the MOA of anticholinergics?
Blocks the effect of acetylcholine and causes sympathetic nervous system
actions to predominate
What is the indication of ipratropium (Atrovent) and tiotropium (Spiriva)?
-Asthma
-COPD
What is the indication for scopolamine (Transderm-Scop)?
-Motion sickness
-Adjunct to anesthesia
,What is the indication for atropine (AtroPen)?
-Increase heart rate
-Dilate pupils
What is the indication for dicyclomine (Bentyl)?
Irritable bowel syndrome
What is the indication for benztropine (Cogentin)?
Parkinson's disease
What are therapeutic uses of anticholinergics?
-GI disorders (IBS)
-Ophthalmic procedures
-Cardiac rhythm abnormalities (bradycardia)
-Anesthesia adjuncts
-Asthma and COPD
-Overactive bladder (urge incontinence)
-Parkinson's disease
What is physostigmine used for?
Too much atropine (anticholinergic)
, What is used as a reversal agent in the event that a patient has too much of
the effects of an anticholinergic?
Physostigmine
What is the primary neurotransmitter of the sympathetic nervous system?
Norepinephrine
What are other neurotransmitters of the sympathetic nervous system?
-Dopamine
-Epinephrine
What are the receptors of the sympathetic nervous system called?
Adrenergic receptors
What are the two types of adrenergic receptors?
-Alpha receptors
-Beta receptors
What are the subdivisions of alpha receptors and beta receptors?
-Alpha-1/α1
-Alpha-2/α2
-Beta-1/β1
-Beta-2/β2
-Beta-3/β3