NURS 6501 FINAL EXAMS 1 AND 2 2026 EXAM
PREPARATION PACK KEY DISEASE
MECHANISMS CELLULAR RESPONSE AND
CLINICAL MANIFESTATIONS WITH SAMPLE
QUESTIONS
◉ Bupropion
- MOA
- BENFITS
AE
CONTRA Answer: MOA
- act to inhibit reuptake of NE, dopamine, and serotonin
BENFIT
- Depression
- Smoking cessation
- Seasonal affective disorder
- Treat sexual dysfunction relative to SSRI therapy
AE
- weight loss
,- increases libido ⇒ combine with SSRI
- can cause seizures by lowering the seizure threshold
CONTRA
- History of seizures
- Do not prescribe to pts with psych disorders ⇒ ↑ risk for delusions
or hallucinations
◉ RF for ETOH abuse 4 Answer: Younger adults (18-29 yrs)
Men > women
Native americans
Genetics (low response to ETOH), environment (peer influences),
specific personality traits (impulsivity, extroversion), cognitive fxn
◉ What are predisposing factors impacting the likelihood of
someone developing a SA issue? Answer: Predisposing Factors:
- Unhealthy use of one substance increases the likelihood of
unhealthy use of other substances
- Family history
- Social history
- Partner or friends with SA, living in a community with poverty,
violence, and/or high ETOH/drug use
, Use of:
- Caffeine, tobacco, ETOH, prescription meds, marijuana, illicit drugs
- Mental health disorders
- Highest in personality disorders
◉ What is withdrawal Answer: process of removal of the drug of
dependence from the body
◉ SS of substance abuse withdrawal 3 Answer: Can last days to
weeks
- NVD
- Flu-like SS: lacrimation, rhinorrhea, diaphoresis, shivering,
piloerection
- SNS/CNS Arousal: mydriasis, mild HTN and tachy, anxiety,
irritability, insomnia, agitation, restless leg, general restlessness,
tremor, low grade temp
◉ Which medications are central nervous system sedatives?
Answer: Include sedatives, tranquilizers, hypnotics
- Good for treating anxiety, panic, acute stress reactions, sleep
disorders
Examples:
Benzos:
PREPARATION PACK KEY DISEASE
MECHANISMS CELLULAR RESPONSE AND
CLINICAL MANIFESTATIONS WITH SAMPLE
QUESTIONS
◉ Bupropion
- MOA
- BENFITS
AE
CONTRA Answer: MOA
- act to inhibit reuptake of NE, dopamine, and serotonin
BENFIT
- Depression
- Smoking cessation
- Seasonal affective disorder
- Treat sexual dysfunction relative to SSRI therapy
AE
- weight loss
,- increases libido ⇒ combine with SSRI
- can cause seizures by lowering the seizure threshold
CONTRA
- History of seizures
- Do not prescribe to pts with psych disorders ⇒ ↑ risk for delusions
or hallucinations
◉ RF for ETOH abuse 4 Answer: Younger adults (18-29 yrs)
Men > women
Native americans
Genetics (low response to ETOH), environment (peer influences),
specific personality traits (impulsivity, extroversion), cognitive fxn
◉ What are predisposing factors impacting the likelihood of
someone developing a SA issue? Answer: Predisposing Factors:
- Unhealthy use of one substance increases the likelihood of
unhealthy use of other substances
- Family history
- Social history
- Partner or friends with SA, living in a community with poverty,
violence, and/or high ETOH/drug use
, Use of:
- Caffeine, tobacco, ETOH, prescription meds, marijuana, illicit drugs
- Mental health disorders
- Highest in personality disorders
◉ What is withdrawal Answer: process of removal of the drug of
dependence from the body
◉ SS of substance abuse withdrawal 3 Answer: Can last days to
weeks
- NVD
- Flu-like SS: lacrimation, rhinorrhea, diaphoresis, shivering,
piloerection
- SNS/CNS Arousal: mydriasis, mild HTN and tachy, anxiety,
irritability, insomnia, agitation, restless leg, general restlessness,
tremor, low grade temp
◉ Which medications are central nervous system sedatives?
Answer: Include sedatives, tranquilizers, hypnotics
- Good for treating anxiety, panic, acute stress reactions, sleep
disorders
Examples:
Benzos:
