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Lehninger Principles of Biochemistry 7th Edition Study Guide – Nelson & Cox | Practice MCQs with Explanations | Complete Chapter Review

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This study resource is designed for Lehninger Principles of Biochemistry, Seventh Edition by David L. Nelson and Michael M. Cox. It provides a structured collection of practice multiple-choice questions with clear explanations to support learning and exam preparation. The material covers all major biochemistry topics, including protein structure and function, enzyme kinetics, metabolism, bioenergetics, carbohydrate metabolism, lipid metabolism, nucleic acids, and gene expression. The questions are organized to help students review concepts step by step and strengthen their understanding. Each question is supported with an explanation to make complex biochemical concepts easier to understand. This helps improve problem-solving skills and prepares students for quizzes, midterm exams, and final assessments. This resource is ideal for students studying biochemistry, medicine, biology, and related fields. It supports both detailed study and quick revision, making it useful for classroom learning and self-study. By using this guide, students can practice effectively, revise key topics, and improve confidence before exams.

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TEST BANK

,Chapter 1. The Foundations of Biochemistry
(Answers are at the End of Each Chapter)
1. In a bacterial cell, the DNA is in the:
A) cell envelope.
B) cell membrane.
C) nucleoid.
D) nucleus.
E) ribosomes.


2. A major change occurring in the evolution of eukaryotes from prokaryotes was the
development of:
A) DNA.
B) photosynthetic capability.
C) plasma membranes.
D) ribosomes.
E) the nucleus.


3. In eukaryotes, the nucleus is enclosed by a double membrane called the:
A) cell membrane.
B) nuclear envelope.
C) nucleolus.
D) nucleoplasm.
E) nucleosome.


4. The dimensions of living cells are limited, on the lower end by the minimum number of
biomolecules necessary for function, and on the upper end by the rate of diffusion of
solutes such as oxygen. Except for highly elongated cells, they usually have lengths and
diameters in the range of:
A) 0.1 m to 10 m.
B) 0.3 m to 30 m.
C) 0.3 m to 100 m.
D) 1 m to 100 m.
E) 1 m to 300 m.


5. Which group of single-celled microorganisms has many members found growing in
extreme environments?
A) bacteria
B) archaea
C) eukaryotes
D) heterotrophs
E) None of the answers is correct.


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, 6. The bacterium E. coli requires simple organic molecules for growth and energy—it is
therefore a:
A) chemoautotroph.
B) chemoheterotroph.
C) lithotroph.
D) photoautotroph.
E) photoheterotroph.


7. Which is a list of organelles?
A) mitochondria, chromatin, endoplasmic reticulum
B) peroxisomes, lysosomes, plasma membrane
C) proteasomes, peroxisomes, lysosomes
D) mitochondria, endoplasmic reticulum, peroxisomes
E) All of the answers are correct.


8. Which list has the cellular components arranged in order of INCREASING size?
A) amino acid < protein < mitochondrion < ribosome
B) amino acid < protein < ribosome < mitochondrion
C) amino acid < ribosome < protein < mitochondrion
D) protein < amino acid < mitochondrion < ribosome
E) protein < ribosome < mitochondrion < amino acid


9. The three-dimensional structure of macromolecules is formed and maintained primarily
through noncovalent interactions. Which one of the following is NOT considered a
noncovalent interaction?
A) carbon-carbon bonds
B) hydrogen bonds
C) hydrophobic interactions
D) ionic interactions
E) van der Waals interactions


10. Which element is NOT among the four most abundant in living organisms?
A) carbon
B) hydrogen
C) nitrogen
D) oxygen
E) phosphorus




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, 11. The four covalent bonds in methane (CH4) are arranged around carbon to give which
geometry?
A) linear
B) tetrahedral
C) trigonal bipyramidal
D) trigonal planar
E) trigonal pyramidal


12. What functional groups are present on this molecule?




A) ether and aldehyde
B) hydroxyl and aldehyde
C) hydroxyl and carboxylic acid
D) hydroxyl and ester
E) hydroxyl and ketone


13. The macromolecules that serve in the storage and transmission of genetic information
are:
A) carbohydrates.
B) lipids.
C) membranes.
D) nucleic acids.
E) proteins.


14. Stereoisomers that are nonsuperimposable mirror images of each other are known as:
A) anomers.
B) cis-trans isomers.
C) diastereoisomers.
D) enantiomers.
E) geometric isomers.


15. The catalog of all proteins functioning in a cell is the:
A) metabolome.
B) proteasome.
C) lysosome.
D) proteome.
E) genome.



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