MSN 570 Advanced Pathophysiology Newest
Version (2026) Real Questions and Verified
Answers 100% Correct (A+)
• Types of Non-Small Cell Carcinoma -✓✓Squamous Cell, Adenocarcinomas, Large
Cell, Bronchial Carcinoid
• ICP in Superior Vena Cava Syndrome -✓✓Excess collection of blood in the head
causing Increase ICP, increased risk in aneurysms and rupture, Can lead to venous
stroke (rare), headache, cerebral edema, papillodema
• Causes of Superior Vena Cava Syndrome -✓✓external tumor compression on vessel,
blood clot(s) inside vessel
• Carcinoid syndrome -✓✓Caused by systemic release in vasoactive substances
including Serotonin (5-HT) and Kalliklein
• Lung Cancer -✓✓2nd most common cancer
• Terminal hematuria (at end of urination) -✓✓blood presents at the end of urination.
Indicates a problem in bladder or prostate and can be seen in advanced prostate
adenocarcinoma
• What does PTHrP cause? -✓✓Hypercalcemia in Squamous Cell Carcinoma
• Treatment associated with Localized Adenocarcinoma -✓✓Surgical Resection
• Microscopic finding or histological description is most likely associated with
Adenocarcinoma of the lung? -✓✓Glandular Pattern
• Tumor location in Adenocarcinoma of the lung -✓✓Peripheral location
• Histology study associated with Adenocarcinoma of the lung? -✓✓Mucin Stain
• Mucin Stain -✓✓Stain + derived from mucous producing glands
• Adenocarcinoma of the lungs is most common among_____________? -✓✓Non-
Smokers
• Most Common Lung Cancer -✓✓Adenocarcinoma (1/2 lung cancer cases)
,• Pathophysiology of Adenocarcinoma of the lungs? -✓✓Mutates: KRA, EGFR, ALK,
Important to analyze tumor tissue, drugs that target/inhibit molecular pathway
• Clinical Features associated with Adenocarcinoma of the Lungs? -✓✓Clubbing,
Hemoptysis
• Treatment for metastatic Adenocarcinoma of the lung -✓✓Chemotherapy and
Radiation
• Which test results, or markers is most often used to diagnose Bronchial Carcinoid
Tumor? -✓✓5-HIAA in Urine
• Microscopic finding or histological description is best associated with Bronchial
Carcinoid Tumor? -✓✓Chromogranin A +, Nests of Neuroendocrine cells
• Systemic disease associated with Bronchial Carcinoid Tumor characterized by release
of Vasoactive substances known as ___________? -✓✓Carcinoid Syndrome
• Treatments most likely indicated for Bronchial Carcinoid Tumor? -✓✓Surgical
Resection, Octreotide for symptomatic relief
• Signs/Symptoms or diseases most likely to be seen in a patient with Bronchial
Carcinoid Tumor? -✓✓Flushing, Wheezing, Diarrhea
• Facts best describe Bronchial Carcinoid Tumor -✓✓Excellent Prognosis, Bronchial
obstruction, Asymptomatic
• Indicated treatments for Large Cell Carcinoma -✓✓Surgical Resection
• Most accurate regarding diagnosis of Large Cell Carcinoma -✓✓Diagnosis of
Exclusion
• Cell Types most closely relates to Large Cell Carcinoma -✓✓Anaplastic cells,
Pleomorphic giant cells
• Description most closely associated with Large Cell Carcinoma -✓✓Poor prognosis,
5yr survival rate is around 10%
• Assessment findings of patient with Large Cell Carcinoma -✓✓Galactorrhea,
peripheral lesions, gynecomastia
• Most true of Large Cell Carcinoma -✓✓Less responsive to chemo/radiation, strong
correlation with smoking, May produce Beta hCG
, • Paraneoplastic syndrome is best associated with Small Cell Carcinoma -✓✓Cushings
Syndrome, Lambert Eaton Syndrome (LEMS), Ectopic ACTH, SIADH
• Most common genetic or chromosomal trait Small Cell Carcinoma -✓✓Amplification
myc oncogenes
• Treatment associated with Small Cell Carcinoma -✓✓Chemotherapy and Radiation
• Thoracic location of Small Cell Carcinoma -✓✓Central
• Microscopic finding or histological description associated with Small Cell Carcinoma -
✓✓Neuron Specific Enolase Positive, Kulchitsky Cells, Chromagranin A +
• Best describes Small Cell Carcinoma -✓✓Aggressively Malignant
• Signs and Symptoms associated with Small Cell Carcinoma -✓✓Narrowing Bronchial
Airways, Strong Correlation with Smoking
• What groups of people are associated with Squamous Cell Carcinoma of the lung? -
✓✓Most Common in men
• Development of Squamous Cell Carcinoma of the Lung -✓✓Strong correlation with
smoking
• Paraneoplastic syndrome best associated with Squamous Cell Carcinoma of the lung -
✓✓PTHrP causes hypercalcemia
• Where does Squamous Cell Carcinoma of the lung develop first? -✓✓Central Location
• Indicated treatment for Squamous Cell Carcinoma of the lung -✓✓Early Stage:
Surgical Resection Late Stage: Chemo/Radiation
• Histological findings with Squamous Cell Carcinoma of the lung -✓✓Keratin Pearls,
Intercellular Bridges, Cavitating lesion extending to the Hilum
• Most appropriate superior vena cava syndrome -✓✓Treat underlying disorders,
increase HOB to decrease amount of congestion at the top of the body, anticoagulation
therapy, catheter directed thrombolysis, chemo/radiation
• Most likely cause of Superior Vena Cava Syndrome -✓✓Tumor; compression of the
mediastinum
Thrombosis
Version (2026) Real Questions and Verified
Answers 100% Correct (A+)
• Types of Non-Small Cell Carcinoma -✓✓Squamous Cell, Adenocarcinomas, Large
Cell, Bronchial Carcinoid
• ICP in Superior Vena Cava Syndrome -✓✓Excess collection of blood in the head
causing Increase ICP, increased risk in aneurysms and rupture, Can lead to venous
stroke (rare), headache, cerebral edema, papillodema
• Causes of Superior Vena Cava Syndrome -✓✓external tumor compression on vessel,
blood clot(s) inside vessel
• Carcinoid syndrome -✓✓Caused by systemic release in vasoactive substances
including Serotonin (5-HT) and Kalliklein
• Lung Cancer -✓✓2nd most common cancer
• Terminal hematuria (at end of urination) -✓✓blood presents at the end of urination.
Indicates a problem in bladder or prostate and can be seen in advanced prostate
adenocarcinoma
• What does PTHrP cause? -✓✓Hypercalcemia in Squamous Cell Carcinoma
• Treatment associated with Localized Adenocarcinoma -✓✓Surgical Resection
• Microscopic finding or histological description is most likely associated with
Adenocarcinoma of the lung? -✓✓Glandular Pattern
• Tumor location in Adenocarcinoma of the lung -✓✓Peripheral location
• Histology study associated with Adenocarcinoma of the lung? -✓✓Mucin Stain
• Mucin Stain -✓✓Stain + derived from mucous producing glands
• Adenocarcinoma of the lungs is most common among_____________? -✓✓Non-
Smokers
• Most Common Lung Cancer -✓✓Adenocarcinoma (1/2 lung cancer cases)
,• Pathophysiology of Adenocarcinoma of the lungs? -✓✓Mutates: KRA, EGFR, ALK,
Important to analyze tumor tissue, drugs that target/inhibit molecular pathway
• Clinical Features associated with Adenocarcinoma of the Lungs? -✓✓Clubbing,
Hemoptysis
• Treatment for metastatic Adenocarcinoma of the lung -✓✓Chemotherapy and
Radiation
• Which test results, or markers is most often used to diagnose Bronchial Carcinoid
Tumor? -✓✓5-HIAA in Urine
• Microscopic finding or histological description is best associated with Bronchial
Carcinoid Tumor? -✓✓Chromogranin A +, Nests of Neuroendocrine cells
• Systemic disease associated with Bronchial Carcinoid Tumor characterized by release
of Vasoactive substances known as ___________? -✓✓Carcinoid Syndrome
• Treatments most likely indicated for Bronchial Carcinoid Tumor? -✓✓Surgical
Resection, Octreotide for symptomatic relief
• Signs/Symptoms or diseases most likely to be seen in a patient with Bronchial
Carcinoid Tumor? -✓✓Flushing, Wheezing, Diarrhea
• Facts best describe Bronchial Carcinoid Tumor -✓✓Excellent Prognosis, Bronchial
obstruction, Asymptomatic
• Indicated treatments for Large Cell Carcinoma -✓✓Surgical Resection
• Most accurate regarding diagnosis of Large Cell Carcinoma -✓✓Diagnosis of
Exclusion
• Cell Types most closely relates to Large Cell Carcinoma -✓✓Anaplastic cells,
Pleomorphic giant cells
• Description most closely associated with Large Cell Carcinoma -✓✓Poor prognosis,
5yr survival rate is around 10%
• Assessment findings of patient with Large Cell Carcinoma -✓✓Galactorrhea,
peripheral lesions, gynecomastia
• Most true of Large Cell Carcinoma -✓✓Less responsive to chemo/radiation, strong
correlation with smoking, May produce Beta hCG
, • Paraneoplastic syndrome is best associated with Small Cell Carcinoma -✓✓Cushings
Syndrome, Lambert Eaton Syndrome (LEMS), Ectopic ACTH, SIADH
• Most common genetic or chromosomal trait Small Cell Carcinoma -✓✓Amplification
myc oncogenes
• Treatment associated with Small Cell Carcinoma -✓✓Chemotherapy and Radiation
• Thoracic location of Small Cell Carcinoma -✓✓Central
• Microscopic finding or histological description associated with Small Cell Carcinoma -
✓✓Neuron Specific Enolase Positive, Kulchitsky Cells, Chromagranin A +
• Best describes Small Cell Carcinoma -✓✓Aggressively Malignant
• Signs and Symptoms associated with Small Cell Carcinoma -✓✓Narrowing Bronchial
Airways, Strong Correlation with Smoking
• What groups of people are associated with Squamous Cell Carcinoma of the lung? -
✓✓Most Common in men
• Development of Squamous Cell Carcinoma of the Lung -✓✓Strong correlation with
smoking
• Paraneoplastic syndrome best associated with Squamous Cell Carcinoma of the lung -
✓✓PTHrP causes hypercalcemia
• Where does Squamous Cell Carcinoma of the lung develop first? -✓✓Central Location
• Indicated treatment for Squamous Cell Carcinoma of the lung -✓✓Early Stage:
Surgical Resection Late Stage: Chemo/Radiation
• Histological findings with Squamous Cell Carcinoma of the lung -✓✓Keratin Pearls,
Intercellular Bridges, Cavitating lesion extending to the Hilum
• Most appropriate superior vena cava syndrome -✓✓Treat underlying disorders,
increase HOB to decrease amount of congestion at the top of the body, anticoagulation
therapy, catheter directed thrombolysis, chemo/radiation
• Most likely cause of Superior Vena Cava Syndrome -✓✓Tumor; compression of the
mediastinum
Thrombosis
