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ONS/ONCC Chemotherapy Immunotherapy Certificate UPDATED ACTUAL QUESTIONS AND CORRECT ANSWERS

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ONS/ONCC Chemotherapy Immunotherapy Certificate UPDATED ACTUAL QUESTIONS AND CORRECT ANSWERS Lesson 1: Foundations to Set the Stage - CORRECT ANSWER Focusing on Cellular Structure and Function - CORRECT ANSWER The Normal Cell Cycle - CORRECT ANSWER -The cell cycle refers to the ordered seres of processes of DNA replication and mitosis, or cell division -Cell nucleus regulates these processes by gathering and processing complexes molecular information Interphase and Mitotic Phase - CORRECT ANSWER through these two major phases During interphase: - CORRECT ANSWER Cell division produces two identical cells Cell grows and DNA is replicated through the following three steps: 1: First growth phase (G1 or first gap) 2: Synthesis phase (S phase) 3:Mitotic Phse (M phase) First Growth Phase (G1 or first gap) - CORRECT ANSWER -reproduce RNA -cells increase in size -"quality assurance" test that the cell will be ready to synthesis DNA -Length of time is variable, can be from hours to days Synthesis Phase (S phase) - CORRECT ANSWER -DNA replicates

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Institution
Chemotherapy
Course
Chemotherapy

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ONS/ONCC Chemotherapy
Immunotherapy Certificate UPDATED
ACTUAL QUESTIONS AND CORRECT
ANSWERS
Lesson 1: Foundations to Set the Stage - CORRECT ANSWER



Focusing on Cellular Structure and Function - CORRECT ANSWER



The Normal Cell Cycle - CORRECT ANSWER -The cell cycle refers to the ordered seres of
processes of DNA replication and mitosis, or cell division



-Cell nucleus regulates these processes by gathering and processing complexes molecular information



Interphase and Mitotic Phase - CORRECT ANSWER Cell division produces two identical cells
through these two major phases



During interphase: - CORRECT ANSWER Cell grows and DNA is replicated through the
following three steps:



1: First growth phase (G1 or first gap)



2: Synthesis phase (S phase)



3:Mitotic Phse (M phase)



First Growth Phase (G1 or first gap) - CORRECT ANSWER -cells increase in size



-reproduce RNA

,-"quality assurance" test that the cell will be ready to synthesis DNA



-Length of time is variable, can be from hours to days



Synthesis Phase (S phase) - CORRECT ANSWER -DNA replicates



-Results in the formation of identical pairs of DNA (chromatids)



-which are attached a t the centromere



-lasts 2-10 hours



Mitotic Phase (M phase) - CORRECT ANSWER -Replicated chromosomes are aligned,
separated, and move into 2 new, identical daughter cells



-takes about 30-60 minutes



Major points of cell regulation are entry and exit from - CORRECT ANSWER -G1 checkpoint



-S Phase



-G2 checkpoint



-M phase



Restriction Point - CORRECT ANSWER -The transition from the resting phase into an actively
dividing phase (G0-G1) is a point where cellular transformation can occur



-During this time, cells pass through a transition phase known as a restriction point

, -Extracellular growth factors trigger reentry into G1, and GF are required to send the cells past the
restriction point, or the point of no return



G0 Phase (resting phase) - CORRECT ANSWER -After mitosis, cells may enter back into the
G1 phase or go into a resting phase, known as G0



-Most cells in the human body reside in G0



-Exceptions to this are those that are (Resting in G0 phase) - CORRECT ANSWER -Exceptions
to this are those that are metabollically active, such as



-granulocytes



-and the epithelium of the GI tract



Cell Cycling Time - CORRECT ANSWER Amount of time from mitosis to mitosis



Cell cycle video and image - CORRECT
ANSWER http://highered.mheducation.com/sites/0072495855/student_view0/chapter2/animati
on__how_the_cell_cycle_works.html



Check points in the Cell Cycle: Keeping it All Under Control - CORRECT ANSWER -The cell
cycle is carefully controlled through a series of checkpoints



-Variation in duplication or distribution of chromosomes during cell division can alter the genetic
information passed on to daughter cells, leading to cellular dysfunction and disease, such as cancer



-These checkpoints monitor for DNA integrity and control progression through mitosis



Progression through the cell cycle is controlled through two proteins: - CORRECT
ANSWER 1. cyclines (D, E, A, B)



2. Cyclin-dependent kinases (CDKs)

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